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Full-Text Articles in Medicine and Health Sciences
Bioengineered Lysozyme Reduces Bacterial Burden And Inflammation In A Murine Model Of Mucoid Pseudomonas Aeruginosa Lung Infection, Charlotte C. Teneback, Thomas C. Scanlon, Matthew J. Wargo, Jenna L. Bement, Karl E. Griswold, Laurie W. Leclair
Bioengineered Lysozyme Reduces Bacterial Burden And Inflammation In A Murine Model Of Mucoid Pseudomonas Aeruginosa Lung Infection, Charlotte C. Teneback, Thomas C. Scanlon, Matthew J. Wargo, Jenna L. Bement, Karl E. Griswold, Laurie W. Leclair
Dartmouth Scholarship
The spread of drug-resistant bacterial pathogens is a growing global concern and has prompted an effort to explore potential adjuvant and alternative therapies derived from nature's repertoire of bactericidal proteins and peptides. In humans, the airway surface liquid layer is a rich source of antibiotics, and lysozyme represents one of the most abundant and effective antimicrobial components of airway secretions. Human lysozyme is active against both Gram-positive and Gram-negative bacteria, ac
Changes In The Bioactive Protein Concentrations In The Bovine Colostrum Of Jersey And Polish Holstein–Friesian Cows, Monika Sobczuk-Szul, Zofia Wielgosz-Groth, Marek Wronski, Arkadiusz Rzemieniewski
Changes In The Bioactive Protein Concentrations In The Bovine Colostrum Of Jersey And Polish Holstein–Friesian Cows, Monika Sobczuk-Szul, Zofia Wielgosz-Groth, Marek Wronski, Arkadiusz Rzemieniewski
Turkish Journal of Veterinary & Animal Sciences
The aim of this study was to determine changes in the bioactive protein concentrations in the bovine colostrum of Jersey and Polish Holstein-Friesian (PHF) cows. Double colostrum samples were collected from 16 Jersey and PHF cows, during 8 successive milking runs after calving. A total of 256 colostrum samples were analyzed to determine the pH, density, percentage share, and content of selected bioactive proteins, including the percentage share of casein fractions (\alpha_s-, \beta-, \gamma-, and \kappa-) in the total casein, and the concentrations of \alpha-lactalbumin (\alpha-LA), \beta-lactoglobulin (\beta-LG), lactoferrin (LF), interleukin-1\beta, interleukin-6, and tumor necrosis factor-alpha. The concentrations of the …