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In Adult Patients With Acute Pyelonephritis, Is Levofloxacin A More Effective Treatment Than Ciprofloxacin?, Gabrielle V. Krekstein
In Adult Patients With Acute Pyelonephritis, Is Levofloxacin A More Effective Treatment Than Ciprofloxacin?, Gabrielle V. Krekstein
PCOM Physician Assistant Studies Student Scholarship
OBJECTIVE: The objective of this systematic review is to determine whether or not levofloxacin is a more effective treatment than ciprofloxacin in adult patients with Acute Pyelonephritis (AP).
STUDY DESIGN: Review of three English language primary double-blind randomized controlled trial studies comparing levofloxacin to ciprofloxacin for the treatment of AP in adults.
DATA SOURCES: Randomized controlled double-blind comparative trials were found using Cochrane, PubMed, and Science Direct databases.
OUTCOME MEASURED: All studies measured three outcomes: microbiologic eradication, clinical response, and safety and tolerability of the medication. Microbiologic eradication was measured by urine culture which demonstrated a reduction of pathogens to/mL. …