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Articles 1 - 4 of 4
Full-Text Articles in Medicine and Health Sciences
The Evaluation Of Water Quality And Weather Patterns As Indicators For Escherichia Coli In Slaters Creek Watershed In Millersville, Tennessee, Jacqueline Brown
The Evaluation Of Water Quality And Weather Patterns As Indicators For Escherichia Coli In Slaters Creek Watershed In Millersville, Tennessee, Jacqueline Brown
Mahurin Honors College Capstone Experience/Thesis Projects
Water quality sampling was conducted in conjunction with the city of Millersville, Tennessee in order to assess levels of Escherichia coli (E. coli) in Slaters Creek. The city of Millersville is under a storm water National Pollutant Discharge Elimination System (NPDES) permit that requires compliance monitoring. In the past, monitoring of E. coli has resulted in noncompliance with state water quality regulations. A water quality assessment, including E. coli and water quality parameters, was conducted to determine if E. coli levels varied between dates within the study area. Statistical methods were utilized to determine if variations existed between the sampling …
The Reaction Of Methionine With A Non-C2-Symmetrical Platinum (Ii) Diamine Compound, Nilesh Sahi
The Reaction Of Methionine With A Non-C2-Symmetrical Platinum (Ii) Diamine Compound, Nilesh Sahi
Mahurin Honors College Capstone Experience/Thesis Projects
The research that we have conducted has allowed us to discover that the amino acids, methionine (Met) and N-acetyl methionine (N-AcMet), will react in a 1:1 and 1:2 molar ratio with platinum complexes containing bulky diamine ligands. Previous research has allowed us to gain a plethora of information on the experimentation and results of specific bulky diamine ligands such as N,N,N',N'-tetramethylethylenediamine and N,N-diethylethylenediamine. In the current study, we have investigated the bulky diamine ligand of N,N-dimethylethylenediamine, or Me2en. With our focus on the bulk of the Me2en ligand, we have been able to synthesize a platinum …
Biomass Assisted Synthesis Of Antibacterial Gold Nanoparticles And Commentary On Its Future Potential And Applications In Medicine, Chad Willis
Mahurin Honors College Capstone Experience/Thesis Projects
Xylose is a natural monosaccharide found in biomass such as straw, pecan shells, cottonseed hulls, and corncobs. Using this monosaccharide, we report the green synthesis and characterization of biocompatible, biodegradable xylose encapsulated gold nanoparticles (Xyl-GNPs) with potential antibacterial activity. GNPs were synthesized using the bioreduction property of xylose on the chloroaurate anions in an aqueous solution at room temperature and at atmospheric pressure. The characterization of synthesized GNPs was examined by UV-vis spectroscopy; transmission electron microscopy (TEM), energy-dispersive x-ray spectroscopy (EDS) and fourier transform infrared spectroscopy (FTIR). Results indicate that the particles were stable; near spherical in shape with an …
Oxaliplatin And Oxaliplatin Derivatives: Synthesis, Characterization, And Reactivity With Biologically Relevant Ligands, Amy Poynter
Mahurin Honors College Capstone Experience/Thesis Projects
Oxaliplatin is a third generation anticancer drug that has proven to be successful in fighting ovarian and testicular cancer. We are interested in determining how oxaliplatin and oxaliplatin derivatives interact with proteins, as well as how that interaction is affected by the size and shape of these platinum compounds. We have synthesized oxaliplatin as it is used in cancer treatment, as well as similar platinum compounds with the same diaminocyclohexane ligand as oxaliplatin but with additional bulk added to the nitrogen atoms. We are reacting oxaliplatin with key amino acids, including methionine, and will be comparing the kinetics of this …