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Full-Text Articles in Medicine and Health Sciences
Lonomics Atlas: A Tool To Explore Interconnected Ionomic, Genomic And Environmental Data, Eduard Dragut, Amgad Madkour, Mohamed Nabeel, Peter Baker, Mourad Ouzzani, David Salt
Lonomics Atlas: A Tool To Explore Interconnected Ionomic, Genomic And Environmental Data, Eduard Dragut, Amgad Madkour, Mohamed Nabeel, Peter Baker, Mourad Ouzzani, David Salt
Cyber Center Publications
Ionomics Atlas facilitates access, analysis and interpretation of an existing large-scale heterogeneous dataset consisting of ionomic (elemental composition of an organism), ge- netic (heritable changes in the DNA of an organism) and ge- ographic information (geographic location, altitude, climate, soil properties, etc). Ionomics Atlas allows connections to be made between the genetic regulation of the ionome of plant populations and their landscape distribution, allowing scientists to investigate the role of natural ionomic variation in adaptation of populations to varied environmental conditions in the landscape. The goal of the Ionomics Atlas is twofold: (1) to allow both novice and expert users …
The Bench Scientist's Guide To Statistical Analysis Of Rna-Seq Data, Craig R. Yendrek, Elizabeth A. Ainsworth, Jyothi Thimmapuram
The Bench Scientist's Guide To Statistical Analysis Of Rna-Seq Data, Craig R. Yendrek, Elizabeth A. Ainsworth, Jyothi Thimmapuram
Cyber Center Publications
RNA sequencing (RNA-Seq) is emerging as a highly accurate method to quantify transcript abundance. However, analyses of the large data sets obtained by sequencing the entire transcriptome of organisms have generally been performed by bioinformatics specialists. Here we provide a step-by-step guide and outline a strategy using currently available statistical tools that results in a conservative list of differentially expressed genes. We also discuss potential sources of error in RNA-Seq analysis that could alter interpretation of global changes in gene expression.
Whole-Genome Resequencing Of Two Elite Sires For The Detection Of Haplotypes Under Selection In Dairy Cattle Supporting Information, Denis M. Larkin, Hans D. Daetwyler, Alvaro G. Hernandez, Chris L. Wright, Lorie A. Hetrick, Lisa Boucek, Sharon Bachman, Jyothi Thimmapuram
Whole-Genome Resequencing Of Two Elite Sires For The Detection Of Haplotypes Under Selection In Dairy Cattle Supporting Information, Denis M. Larkin, Hans D. Daetwyler, Alvaro G. Hernandez, Chris L. Wright, Lorie A. Hetrick, Lisa Boucek, Sharon Bachman, Jyothi Thimmapuram
Cyber Center Publications
Using a combination of whole-genome resequencing and high-density genotyping arrays, genome-wide haplotypes were reconstructed for two of the most important bulls in the history of the dairy cattle industry, Pawnee Farm Arlinda Chief (“Chief”) and his son Walkway Chief Mark (“Mark”), each accounting for ∼7% of all current genomes. We aligned 20.5 Gbp (∼7.3× coverage) and 37.9 Gbp (∼13.5× coverage) of the Chief and Mark genomic sequences, respectively. More than 1.3 million high-quality SNPs were detected in Chief and Mark sequences. The genome-wide haplotypes inherited by Mark from Chief were reconstructed using ∼1 million informative SNPs. Comparison of a set …
Artl@ S And Basart: A Loose Coupling Strategy For Digital Humanities, Sorin Matei
Artl@ S And Basart: A Loose Coupling Strategy For Digital Humanities, Sorin Matei
Cyber Center Publications
The core ARTL@S digital humanities
strategy is that of loosely coupling
resources, platforms, and use scenarios.
A number of sites will feed from
the same geodatabase (BasArt),
which will be enriched by users with
new content. Inspired by the Web 2.0
design principles, ARTL@S relies on
the BasArt API, which will enable an
ecosystem of sites to use primary
data to generate their own maps,
charts, and tables. A variety of economic
models will also be used to
support the site, from free to paybased.
User-generated content will be
monitored by data management and
curation techniques that will ensure
the …
Authenticated Top-K Aggregation In Distributed And Authenticated Top-K Aggregation In Distributed And, Sunoh Choi, Hyo-Sang Lim, Elisa Bertino
Authenticated Top-K Aggregation In Distributed And Authenticated Top-K Aggregation In Distributed And, Sunoh Choi, Hyo-Sang Lim, Elisa Bertino
Cyber Center Publications
Top-k queries have attracted interest in many different areas like network and system monitoring, information retrieval, sensor networks, and so on. Since today many applications issue top-k queries on distributed and outsourced databases,
authentication of top-k query results becomes more important. This paper addresses the problem of authenticated top-k aggregation queries (e.g. “find the k objects with the highest aggregate values”) in a distributed system. We propose a new algorithm, called Authenticated Three Phase Uniform Threshold (A-TPUT), which provides not only efficient top-k aggregation over distributed databases but also authentication on the top-k results. We also introduce several enhancements for …