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Full-Text Articles in Medicine and Health Sciences

Inter-Study Reproducibility Of Cardiovascular Magnetic Resonance Myocardial Feature Tracking., Geraint Morton, Andreas Schuster, Roy Jogiya, Shelby Kutty, Philipp Beerbaum, Eike Nagel Jun 2012

Inter-Study Reproducibility Of Cardiovascular Magnetic Resonance Myocardial Feature Tracking., Geraint Morton, Andreas Schuster, Roy Jogiya, Shelby Kutty, Philipp Beerbaum, Eike Nagel

Journal Articles: Pediatrics

BACKGROUND: Cardiovascular magnetic resonance myocardial feature tracking (CMR-FT) is a recently described method of post processing routine cine acquisitions which aims to provide quantitative measurements of circumferentially and radially directed ventricular wall strain. Inter-study reproducibility is important for serial assessments however has not been defined for CMR-FT.

METHODS: 16 healthy volunteers were imaged 3 times within a single day. The first examination was performed at 0900 after fasting and was immediately followed by the second. The third, non-fasting scan, was performed at 1400.CMR-FT measures of segmental and global strain parameters were calculated. Left ventricular (LV) circumferential and radial strain were …


Microbubble Mediated Thrombus Dissolution With Diagnostic Ultrasound For The Treatment Of Chronic Venous Thrombi., Shelby Kutty, Juefei Wu, James M. Hammel, Feng Xie, Shunji Gao, Lucas K. Drvol, John Lof, Stanley J. Radio, Stacey L. Therrien, David A. Danford, Thomas R. Porter Jan 2012

Microbubble Mediated Thrombus Dissolution With Diagnostic Ultrasound For The Treatment Of Chronic Venous Thrombi., Shelby Kutty, Juefei Wu, James M. Hammel, Feng Xie, Shunji Gao, Lucas K. Drvol, John Lof, Stanley J. Radio, Stacey L. Therrien, David A. Danford, Thomas R. Porter

Journal Articles: Pediatrics

BACKGROUND: Central venous catheter (CVC) thrombi result in significant morbidity in children, and currently available treatments are associated with significant risk. We sought to investigate the therapeutic efficacy of microbubble (MB) enhanced sonothrombolysis for aged CVC associated thrombi in vivo.

METHODS AND RESULTS: A model of chronic indwelling CVC in the low superior vena cava with thrombus in situ was established after feasibility and safety testing in 7 pigs; and subsequently applied for repeated, sonothrombolytic treatments in 9 pigs (total 24 treatments). Baseline intracardiac echocardiography (ICE, 10.5F, Siemens), fluoroscopy and saline flushing confirmed the absence of any pre-existing CVC thrombus. …