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Event-Related Potential Studies Of Post-Traumatic Stress Disorder: A Critical Review And Synthesis, Arash Javanbakht, Israel Liberzon, Alireza Amirsadri, Klevest Gjini, Nash N. Boutros
Event-Related Potential Studies Of Post-Traumatic Stress Disorder: A Critical Review And Synthesis, Arash Javanbakht, Israel Liberzon, Alireza Amirsadri, Klevest Gjini, Nash N. Boutros
Wayne State University Associated BioMed Central Scholarship
Abstract
Despite the sparseness of the currently available data, there is accumulating evidence of information processing impairment in post-traumatic stress disorder (PTSD). Studies of event-related potentials (ERPs) are the main tool in real time examination of information processing. In this paper, we sought to critically review the ERP evidence of information processing abnormalities in patients with PTSD. We also examined the evidence supporting the existence of a relationship between ERP abnormalities and symptom profiles or severity in PTSD patients. An extensive Medline search was performed. Keywords included PTSD or post-traumatic stress disorder, electrophysiology or EEG, electrophysiology, P50, P100, N100, P2, …