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Laparoscopic Transanal Abdominal Transanal Resection With Sphincter Preservation For Rectal Cancer In The Distal 3 Cm Of The Rectum After Neoadjuvant Therapy., Dr. John Marks, B. Mizrahi, S. Dalane, I. Nweze, Dr. Gerald Marks Nov 2010

Laparoscopic Transanal Abdominal Transanal Resection With Sphincter Preservation For Rectal Cancer In The Distal 3 Cm Of The Rectum After Neoadjuvant Therapy., Dr. John Marks, B. Mizrahi, S. Dalane, I. Nweze, Dr. Gerald Marks

Dr. John Marks

BACKGROUND: This study reports the short- and long-term results for a prospective rectal cancer management program using laparoscopic radical transanal abdominal transanal proctosigmoidectomy with coloanal anastomosis (TATA) after neoadjuvant therapy.

METHODS: A prospective database included 102 rectal cancer patients treated with laparoscopic TATA from 1998 to 2008. Patients with distant metastasis at presentation, patients with a tumor more than 3 cm from the anorectal ring, and patients not undergoing neoadjuvant therapy were excluded, leaving 79 patients (54 men and 25 women) with a mean age of 59.2 years (range, 22-85 years) for this study. 13 patients completed neoadjuvant therapy before …


Cerebral And Choroidal Metastases With Retinal Detachement, Secondary To Rectal Cancer: A Case Report, Dr. John Marks, Dr. Elsa Valsdottir, Dr. Eric Zeger, Dr. Carol Shields Jan 2010

Cerebral And Choroidal Metastases With Retinal Detachement, Secondary To Rectal Cancer: A Case Report, Dr. John Marks, Dr. Elsa Valsdottir, Dr. Eric Zeger, Dr. Carol Shields

Dr. John Marks

Colorectal cancer is the most common abdominal visceral cancer diagnosed in men and in women annually and is estimated that about 106,100 new case of colon cancer and 40, 870 cases of rectal cancer would be diagnosed in 2009.

Metastasis secondary to colorectal cancer will occur in 10-20% of patients The most common metastatic sites of colorectal cancer include, liver metastases and pulmonary metastases. Metastatic brain tumors from colorectal cancer are relatively rare between 1.03 and 1.8%.

Brain metastases in colorectal cancers are rarely encountered. Although not statistically significant, concurrent cerebral and pulmonary metastases were associated with lower rectal tumours …