Medicine and Health Sciences Commons^™

Ethnic Differences In Do-Not-Resuscitate Orders After Intracerebral Hemorrhage, Darin B Zahuranec, Devin L Brown, Lynda D Lisabeth, Nicole R Gonzales, Paxton J Longwell, Melinda A Smith, Nelda M Garcia, Lewis B Morgenstern

Journal Articles

OBJECTIVE: To explore ethnic differences in do-not-resuscitate orders after intracerebral hemorrhage.

DESIGN: Population-based surveillance.

SETTING: Corpus Christi, Texas.

PATIENTS: All cases of intracerebral hemorrhage in the community of Corpus Christi, TX were ascertained as part of the Brain Attack Surveillance in Corpus Christi (BASIC) project.

INTERVENTIONS: None.

MEASUREMENTS AND MAIN RESULTS: Medical records were reviewed for do-not-resuscitate orders. Unadjusted and multivariable logistic regression were used to test for associations between ethnicity and do-not-resuscitate orders, both overall ("any do-not-resuscitate") and within 24 hrs of presentation ("early do-not-resuscitate"), adjusted for age, gender, Glasgow Coma Scale, intracerebral hemorrhage volume, intraventricular hemorrhage, infratentorial hemorrhage, …

Jnk1 Activation Predicts The Prognostic Outcome Of The Human Hepatocellular Carcinoma, Qingshan Chang, Jianguo Chen, Kevin J. Beezhold, Vince Castranova, Xianglin Shi, Fei Chen

Toxicology and Cancer Biology Faculty Publications

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide with an extremely poor prognosis. The classification of HCC based on the molecular signature is not well-established.

RESULTS: In the present study, we reported HCC signature genes based on the JNK1 activation status in 31 HCC specimens relative to the matched distal noncancerous liver tissue from 31 patients. The HCCs with high JNK1 (H-JNK1) and low JNK1 (L-JNK1) were sub-grouped. Two different signature gene sets for both H-JNK1 and L-JNK1 HCC were identified through gene expression profiling. A striking overlap of signature genes was observed between the H-JNK1 …

The Significance Of Gata3 Expression In Breast Cancer: A 10-Year Follow-Up Study., Vincenzo Ciocca, Constantine Daskalakis, Robin M. Ciocca, Alejandra Ruiz-Orrico, Juan P. Palazzo

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

GATA3 is a transcription factor closely associated with estrogen receptor alpha in breast carcinoma, with a potential prognostic utility. This study investigated the immunohistochemical expression of GATA3 in estrogen receptor alpha-positive and estrogen receptor alpha-negative breast carcinomas. One hundred sixty-six cases of invasive breast carcinomas with 10-year follow-up information were analyzed. Positive GATA3 and estrogen receptor alpha cases were defined as greater than 20% of cells staining. Time to cancer recurrence and time to death were analyzed with survival methods. Of 166 patients, 40 were estrogen receptor alpha negative and 121 estrogen receptor alpha positive. Thirty-eight (23%) recurrences and 51 …

Association Of Gucy2c Expression In Lymph Nodes With Time To Recurrence And Disease-Free Survival In Pn0 Colorectal Cancer., Scott A Waldman, Terry Hyslop, Stephanie Schulz, Alan Barkun, Karl Nielsen, Janis Haaf, Christine Bonaccorso, Yanyan Li, David S Weinberg

Department of Pharmacology and Experimental Therapeutics Faculty Papers

CONTEXT: The established relationship between lymph node metastasis and prognosis in colorectal cancer suggests that recurrence in 25% of patients with lymph nodes free of tumor cells by histopathology (pN0) reflects the presence of occult metastases. Guanylyl cyclase 2C (GUCY2C) is a marker expressed by colorectal tumors that could reveal occult metastases in lymph nodes and better estimate recurrence risk.

OBJECTIVE: To examine the association of occult lymph node metastases detected by quantifying GUCY2C messenger RNA, using the reverse transcriptase-polymerase chain reaction, with recurrence and survival in patients with colorectal cancer.

DESIGN, SETTING, AND PARTICIPANTS: Prospective study of 257 patients …

Care Of An Unresponsive Patient With A Poor Prognosis, Arthur Slutsky, Leonard Hudson, Nancy Dubler, Charles Weijer, Mark Tonelli

Charles Weijer

No abstract provided.

Predicting Outcome In Acute Low Back Pain Using Different Models Of Patient Profiling, Benedict M. Wand, James H. Mcauley, Louise Marston, Lorraine H. De Souza

Health Sciences Papers and Journal Articles

Study Design: Prospective observational study of prognostic indicators, utilising data from a randomised, controlled trial of physiotherapy care of acute low back pain (ALBP) with follow up at 6 weeks, 3 months and 6 months.

Objective: To evaluate which patient profile offers the most useful guide to long-term outcome in ALBP.

Summary of Background Data: The evidence used to inform prognostic decision-making is derived largely from studies where baseline data is used to predict future status. Clinicians often see patients on multiple occasions so may profile patients in a variety of ways. It is worth considering if better prognostic decisions …

Health Prognisis Of Electronics Via Power Profiling, Jonathan Amilcar Cervantes

Open Access Theses & Dissertations

The objective of this research is to investigate a new approach for the early detection of latent defects in electronic devices in the field. Reliability is assessed through the non-traditional approach of recording and evaluating the power profile of electronic devices within a deterministic state of operation. Traditionally, measuring the quiescent current (Iddq) of a device has been employed in manufacturing tests to detect defective parts prior to deployment to the field. However, the monitoring of the deterministic power signature (i.e. boot up or during a self-test routine) has never been exploited to monitor the health of a device in …

Artificial Neural Network Analysis For Prediction Of Headache Prognosis In Elderly Patients, Bahar Taşdelen, Sema Helvaci, Hakan Kaleağasi, Aynur Özge

Turkish Journal of Medical Sciences

Aim: To investigate the ability of neural networks to detect and classify the complete improvement of headache in elderly patients during the follow- up period. Materials and Methods: The multilayer perceptron (MLP), which is the most common neural network, was used to predict prognosis of headache in elderly patients. The data set was divided into training and test sets, and back-propagation algorithm was used as the learning algorithm. The accuracies of the models to predict completely improved patients at the end of 20, 40, and 60 months of follow-up were evaluated by means of the areas under the receiver operating …

Demographics, Clinical Presentations And Outcomes Of Cancer Patients Admitting To Emergency Department., Nuri̇ Bozdemi̇r, Oktay Eray, Cenker Eken, Yeşi̇m Şenol, Mehmet Artaç, Mustafa Samur

Turkish Journal of Medical Sciences

Aim: The development of new treatment strategies for cancer patients resulted in an increase of cancer patient visits to emergency departments (EDs). The purpose of this study is to determine clinical characteristics, causes, and predictors of short term prognosis of cancer patient admissions to the ED. Materials and Methods: This prospective, clinical, and observational study was carried out in an adult ED of a tertiary hospital with an annual census of 55,000. All cancer patients visiting the ED within the 6-month period were enrolled into the study and followed up at the 1st and 3rd months afterwards. Records were based …

A New Classification For Ileosigmoid Knotting, S. Selçuk Atamanalp, Gürkan Öztürk, Bülent Aydinli, M. İlhan Yildirgan, Mahmut Başoğlu, Durkaya Ören, Abdul Meci̇t Kantarci

Turkish Journal of Medical Sciences

Aim: This study aimed to establish a new classification that will contribute to the treatment and prognosis of ileosigmoid knotting (ISK), which is a combination of ileum volvulus and sigmoid volvulus (SV). Materials and methods: Based on the SV classification in which criteria associated with mortality, such as age over 60 years and the presence of accompanying disease and/or shock, were used, and a new classification was made for ISK. For this classification, the records of 71 patients with ISK, who were treated surgically, were reviewed retrospectively, and unlike in SV classification, rather than the presence of sigmoid gangrene alone, …