Medicine and Health Sciences Commons^™

Manifest Greatness Version5 By Marc Guerrero With Tato Malay, Emmanuel Mario B. Santos Aka Marc Guerrero

Emmanuel Mario B Santos aka Marc Guerrero

MANIFEST GREATNESS version5 by Marc Guerrero with Tato Malay

Manifest Greatness Version3 By Marc Guerrero With Jay Fajardo, Emmanuel Mario B. Santos Aka Marc Guerrero

Emmanuel Mario B Santos aka Marc Guerrero

MANIFEST GREATNESS version3 by Marc Guerrero with Jay Fajardo

Manifest Greatness Version2 With Danielle Van Asch-Prevot, Emmanuel Mario B. Santos Aka Marc Guerrero

Emmanuel Mario B Santos aka Marc Guerrero

MANIFEST GREATNESS version2 by Marc Guerrero with Danielle van Asch-Prevot

Manifest Greatness... Panahon Ng Mga Filipino Ang 21st Century: Ang Asian Century (Ang Pagpapanumbalik Sa Likas Na Karangalan Ng Lahat Ng Filipino Sa Buong Mundo), Emmanuel Mario B. Santos Aka Marc Guerrero

Emmanuel Mario B Santos aka Marc Guerrero

MANIFEST GREATNESS Panahon ng mga Filipino ang 21st century: Ang Asian Century (Ang pagpapanumbalik sa likas na Karangalan ng lahat ng Filipino sa buong mundo) Manifest Greatness is a work-in-progress Manifesto of, for and by Filipino citizens of the world in synergy with foreign national friends of the Filipino people worldwide in pursuit of genuine entrepreneurial wisdom

Human Amnion As A Novel Cell Delivery Vehicle For Chondrogenic Mesenchymal Stem Cells, Tunku Kamarul Zaman

Tunku Kamarul Zaman

This study investigates the feasibility of processed human amnion (HAM) as a substrate for chondrogenic differentiation of mesenchymal stem cells (MSCs). HAM preparations processed by air drying (AD) and freeze drying (FD) underwent histological examination and MSC seeding in chondrogenic medium for 15 days. Monolayer cultures were used as control for chondrogenic differentiation and HAMs without cell seeding were used as negative control. Qualitative observations were made using scanning electron microscopy analysis and quantitative analyses were based on the sulfated glycosaminoglycans (GAG) assays performed on day 1 and day 15. Histological examination of HAM substrates before seeding revealed a smooth …

Public Policy On Alcohol In The United Kingdom: Towards A Safety Net For The Alcohol-Dependent, Laura Williamson

Dr Laura Williamson

Public policy on alcohol in the United Kingdom fails to support, and may even undermine, the wellbeing of those with the worst alcohol misuse problems, the alcohol-dependent. This is partly because it evades the thorny issue of impaired control that characterises dependence. In addition, until recently, all United Kingdom alcohol policy focused on improving individualised treatment for the dependent, rather than attending to the wider social and environmental factors that influence the condition. The efforts of policy to normalise "sensible" drinking, while stigmatising drunkenness, also risk exacerbating the social vulnerability of the alcohol-dependent. The article examines these issues and concludes …

Income Inequality And Homicide Rates In Sao Paulo, Brazil., Paulo A. Lotufo, Isabela M. Bensenor

Paulo A Lotufo

Description of the epidemic of homicide among poor people in Brazil. In Sao Paulo, Brazil, homicides to men aged 15-44 years increased with an annual percentage change (APC) of 4.7% from 1996 to 2001, and then decreased from 2001 to 2007 with an APC of -14.6%. Analyzing the intra-urban distribution according to family income, the increase in the homicide rate was restricted to men living in the poorest neighbourhoods. In contrast, the decline in homicide rates was observed to men living in all districts. The reasons for this 'up and down' trend are not clear.

Tobacco And Alcohol Use In People Who Have A Learning Disability: Giving Voice To Their Health Promotion Needs, Maggie Lawrence, Susan M. Kerr, Christopher Darbyshire, Alan Middleton, Hazel Watson

Dr. Susan Kerr

Aim The aim of the study was to explore the tobacco and alcohol-related health promotion needs of people with mild/moderate learning disabilities.

Methodology & Methods The design of the study was grounded in the principles of the Medical Research Council’s Framework for the development and evaluation of complex healthcare interventions. Specifically, a developmental approach was adopted, where evidence was gathered and data collected and synthesised to inform the development of subsequent interventions. Systematic review methods were used to facilitate the gathering of evidence regarding the effectiveness of previous tobacco and alcohol-related interventions designed for people with learning disabilities (PwLD). Following …

Occurrence Of Giardia And Cryptosporidium (Oo)Cysts In The River Water Of Two Recreational Areas In Selangor, Malaysia, Init Ithoi

Init Ithoi

This study is the first report on the occurrence of Giardia and Cryptosporidium (oo)cysts in recreational rivers water from Malaysia. It was carried out in water samples at two rivers, 'Sungai Congkak' and 'Sungai Batu', located in Selangor State. The occurrence of both Giardia lamblia and Cryptosporidium parvum (oo)cysts was higher in Sungai Congkak (50% or 15/30 and 10% or 3/30 respectively) than Sungai Batu (16% or 5/30 and 3.3% or 1/30 respectively). The mean density of cysts/L was 0.72 in Sungai Congkak and 0.023 in Sungai Batu, and that of oocysts/L was 0.023 in Sungai Congkak and 0.0033 in …

Effects Of Different Denture Cleansers On The Tensile Bond Strength Of Denture Liners, Selda Keskin

The effect of two denture cleansers (Polident1 and Protefix1) on the tensile bond strength between four soft liner materials (Molloplast B1, Permaflex1, Sofreliner Tough Medium1, and GC Reline Soft1) and a conventional denture base resin was investigated. For each of the liner materials 35 test specimens were prepared according to test the requirements and assigned into seven groups (n¼5). Before tensile testing, five of the liner specimens were kept in water or soaked in two cleansing solutions during 2 and 7 d. Five other samples served as a control group subjected directly to tensile testing. The bond strength values were …

Tensile Bond Strength Of A Highly Cross-Linked Denture Tooth To The, Selda Keskin

This study compared tensile bond strengths between conventional compressionmolded heat (HC)-, auto (AP)-, and microwave-polymerized (MC) poly(methyl methacrylate)-based denture resins and a relatively new injection-molded, microwave-polymerized polyurethane based resin (MI) bonded to a highly cross-linked denture tooth. In the first part of the experiments, denture teeth were used as received. In the second part, they were treated with dichloromethane to see its effect on bonding of conventional denture bases (HCS and APS). Bond strength was tested in tension according to ADA specification No.15. The results showed that the HC group failed cohesively because of higher interface bonding (49.95 MPa) compared …

Operation Outreach: An Ongoing Leadership Project, Lisa Forrest

Lisa A Forrest

No abstract provided.

Itraconazole-Induced Torsade De Pointes In A Patient Receiving Methadone Substitution Therapy, Noorzurani Robson Associate Prof. Dr., B. Vicknasingam, S. Narayanan

Associate Prof. Dr. Noorzurani Robson

Issues. Methadone, a pharmacological agent used to treat heroin dependence is relatively safe, but may cause cardiac arrhythmias in the concurrent presence of other risk factors. Approach and Key Findings. This case report highlights the risk of Torsade de Pointes, a life-threatening cardiac arrhythmia, in a heroin-dependent patient receiving methadone substitution therapy who was prescribed itraconazole for vaginal thrush. The patient presented to the accident and emergency department for chest discomfort and an episode of syncope following two doses of itraconazole (200 mg). Electrocardiogram monitoring at the accident and emergency department showed prolonged rate-corrected QT interval leading to Torsade de …

Ppar Agonists Down-Regulate The Expression Of Atp10c Mrna During Adipogenesis, A Peretich, Maria Cekanova Ms, Rndr, Phd, S Hurst, Sj Baek, Madhu Dahr

Maria Cekanova MS, RNDr, PhD

No abstract provided.

Promoting The Self-Regulation Of Clinical Reasoning Skills In Nursing Students, Ruthanne Kuiper, Daniel J. Pesut, Donald D. Kautz

RuthAnne Kuiper

Abstract: Aim: The purpose of this paper is to describe the research surrounding the theories and models the authors united to describe the essential components of clinical reasoning in nursing practice education. The research was conducted with nursing students in health care settings through the application of teaching and learning strategies with the Self-Regulated Learning Model (SRL) and the Outcome-Present-State-Test (OPT) Model of Reflective Clinical Reasoning. Standardized nursing languages provided the content and clinical vocabulary for the clinical reasoning task.

Materials and Methods: This descriptive study described the application of the OPT model of clinical reasoning, use of nursing language …

Molecular Detection Of Giardia Contamination In Water Bodies In A Zoo, Yvonne Lim Ai Lian

Yvonne Lim Ai Lian

We used a combined microscopy-molecular approach to determine the occurrence and identities of waterborne Giardia sp. cysts isolated from 18 separate, 10l grab samples collected from a Malaysian zoo. Microscopy revealed that 17 of 18 samples were Giardia cyst positive with concentrations ranging from 1 to 120 cysts/l. Nine (52.9%) of the 17 cyst positive samples produced amplicons of which 7 (77.8%) could be sequenced. Giardia duodenalis assemblage A (6 of 7) and assemblage B (1 of 7), both infectious to humans, were identified at all sampling sites at the zoo. The presence of human infectious cysts raises public health …

A Summary Of The Guidance Relating To Four Lifestyle Risk Factors For Recurrent Stroke: Tobacco Use, Alcohol Consumption, Diet And Physical Activity, Maggie Lawrence, Susan Kerr, Hazel Watson, Jennie Jackson, Margaret Brownlee

Dr. Maggie Lawrence

Stroke is a major cause of mortality, disability and family disruption; yet prevalence continues to rise despite advances in prevention and treatment. Many risk factors for stroke are modifi able, including life style behaviours, i.e. tobacco and alcohol use, diet and physical activity. Patterns that infl uence lifestyle behaviour are believed to be embedded in family life. Primary and secondary prevention of stroke are important health promotion issues. The objective of this study was to summarize government recommendations and contemporary evidence-based guidelines regarding four lifestyle risk factors for recurrent stroke.

A Finite Element Study Of The Multilayered Structured Dental Post, Noor Hayaty Abu Kasim Abu Kasim N.H.

Noor Hayaty Abu Kasim Abu Kasim N.H.

Ideally, dental post should have stiffness that is similar to the crown at the coronal part and stiffness similar to the dentine at the apical part. This will reduce stress concentration at either coronal or the apical parts of the dentine and minimize the chance of interfacial loosening and enhance the reliability of post. Objective: To investigate the biomechanical behaviour of Multilayered Structured Dental Posts (MSDPs) using finite element analysis (FEA). Methods: Two models of MSDPs consist of multilayer design of xTi-yHA composition added to a zirconia layer (model A) and the same compositions added to alumina layer (model B) …

Unilateral Refusal Of Treatment And Patient Abandonment: Betancourt V. Trinitas Hospital, Brief Of Amicus Curiae, Law Professor Thaddeus Mason Pope, Thaddeus M. Pope

Thaddeus Mason Pope

Betancourt v. Tinitas Hospital is now pending before the Appellate Division of the New Jersey Superior Court. Trinitas Hospital is appealing a March 2009 trial court injunction, ordering its physicians to continue providing life-sustaining medical treatment (particularly dialysis) that these providers judged to be medically inappropriate and outside the standard of care.

In early 2009, patient Ruben Betancourt was in a permanent vegetative state with multi-organ failure and slim prospects for recovery. Still, the patient’s daughter, Jacqueline, would not accede to recommendations to stop dialysis and switch to palliative care. When it became apparent that providers might unilaterally withdraw Mr. …

Evaluation Of Laparoscopic Appendectomy Vs. Open Appendectomy: A Retrospective Study At Aga Khan University Hospital, Karachi, Pakistan, Tazeen S. Ali Dr, Yasmin Parpio Dr, Shaheena Bhatti Dr, Ghina Shamsi Dr, Yasmin Vellani Dr

Tazeen S Ali Dr

Objective: To compare open and laparoscopic appendectomies and to evaluate the level of efficacy of both types of appendectomy performed at Aga Khan University Hospital (AKUH). Methods: Based on this strong study rationale, a clinical audit of patient's records was performed to evaluate the significance of this technique as a treatment modality. The study population comprised of patients with appendicitis admitted in the Department of Surgery from January 2004 to December 2004. The patients' charts were reviewed to ascertain whether the procedure was done as an acute case or as an elective procedure. The predictor variables explored in this study …

Molecular Characterization Of Giardia Duodenalis Isolated From Semai Pahang Orang Asli (Peninsular Malaysia Aborigines), Yvonne Lim Ai Lian

Yvonne Lim Ai Lian

This study was conducted to determine the genotypes of Giardia duodenalis isolated from human faecal samples at Pos Betau, Pahang, Malaysia. Faecal specimens were collected and examined for G. duodenalis cysts using Trichrome staining techniques. Molecular identification was carried out by the amplification of a region of the small subunit of the nuclear ribosomal RNA (SSU rRNA) gene using nested PCR and subsequent sequencing. The sequences from 15 isolates from G. duodenalis were subjected to phylogenetic analysis (including appropriate outgroups) using the neighbor-joining and maximum parsimony methods. The trees identified G. duodenalis assemblages A and B, with a predominance of …

Dirofilaria Causing Eye Infection In A Patient From Malaysia, Init Ithoi

Init Ithoi

During a study on the quality of the indoor environment, Acanthamoeba spp. were detected in 20 out of 87 dust samples collected from air-conditioners installed in a four-story campus building located in Kuala Lumpur, Malaysia. Twenty-one cloned Acanthamoeba isolates designated as IMU1 to IMU21 were established from the positive primary cultures. Five species were identified from the 16 isolates according to the morphological criteria of Pussard and Pons; i.e. A. castellanii, A. culbertsoni, A. griffini, A. hatchetti and A. polyphaga. Species identities for the remaining five isolates (IMU4, IMU5, IMU15, IMU20 and IMU21), however, could not be determined morphologically. At …

Assessing Risk In Focal Arboviral Infections: Are We Missing The Big Or Little Picture?, A D. Haddow, Agricola Odoi, C J. Jones

Agricola Odoi

BACKGROUND: Focal arboviral infections affecting a subset of the overall population present an often overlooked set of challenges in the assessment and reporting of risk and the detection of spatial patterns. Our objective was to assess the variation in risk when using different at-risk populations and geographic scales for the calculation of incidence risk and the detection of geographic hot-spots of infection. We explored these variations using a pediatric arbovirus, La Crosse virus (LACV), as our model. METHODS AND FINDINGS: Descriptive and cluster analyses were performed on probable and confirmed cases of LACV infections reported to the Tennessee Department of …

Modeling Brain Tumors Using Avian Retroviral Gene Transfer, Tod D. Holland, Eric C. Holland

Tod D Holland

RCAS/tv-a is a system for post-natal cell type specific gene transfer. It is used for the modeling of gliomas and medulloblastomas. This system provides a combination of lineage tracing from the cell origin with oncogenesis induced by mis-expression of specific genes. The genes that are most potent at inducing tumors are those that encode components of signal transduction and undifferentiated cells are most capable of serving as the cell of origin. The system effectively generates tumors with the histologic characteristics of human disease. Mice bearing RVAS/tv-a induced brain tumors are currently being used for preclinical trials to understand the biology …

Gene Expression In Human Oral Squamous Cell Carcinoma Is Influenced By Risk Factor Exposure, Cheong S. C., Chandramouli G. V. R., Saleh A., Rosnah Binti Zain, Lau S. H., Sivakumaren S., Pathmanathan R., Prime S. S., Teo S. H., Patel V., Gutkind J. S.

Prof. Dr. Rosnah Binti Zain

Oral squamous cell carcinoma (OSCC) is a world health problem and is associated with exposure to different risk factors. In the west, smoking and alcohol consumption are considered to be the main risk factors whilst in India and southeast Asia, betel quid (BQ) chewing is predominant. In this study, we compared the gene expression patterns of oral cancers associated with BQ chewing to those caused by smoking using Affymetrix microarrays. We found that 281 genes were differentially expressed between OSCC and normal oral mucosa regardless of aetiological factors including MMP1, PLAU, MAGE-D4, GNA12, IFITM3 and NMU. Further, we identified 168 …

Development Of A Mechanistic Model To Represent The Dynamics Of Particle Flow Out Of The Rumen And To Predict Rate Of Passage Of Forage Particles In Dairy Cattle., S Seo, Cristina Lanzas, L O. Tedeschi, A Pell, D G. Fox

Cristina Lanzas

A mechanistic and dynamic model was developed to represent physiological aspects of particle dynamics in the reticulo-rumen (RR) and to predict rate of passage out of the RR (Kp) of forage particles quantitatively. The model consists of 2 conceptual pools with 3 spatial compartments of particles; the compartment the particle enters is based on functional specific gravity (FSG). The model assumes 2 major pressure gradient-driven flows of particles out of the RR through the reticulo-omasal orifice between 2 consecutive primary reticular contractions. One is associated with the second phase of primary reticular contraction and involves propulsion of particles in the …

Public Health H1n1 Response Research Protocol, Glen Mays

Glen Mays

This research protocol was developed to analyze local variation in the public health response to the 2009 H1N1 influenza outbreak in the United States. The protocol was fielded in North Carolina and Kentucky through practice-based research networks (PBRNs) operating in these states.

Public Health And The Rights Of States, András Miklós

Andras Miklos

When exercising their public health powers, states claim various rights against their subjects and aliens. The paper considers whether public health considerations can help justify some of these rights, and explores some constraints on the justificatory force of public health considerations. I outline two arguments about the moral grounds for states’ rights with regard to public health. The principle of fairness emphasizes that those who benefit from public health measures ought to contribute their fair share in upholding them. Alternatively, states’ rights might be justified by a natural duty of justice to uphold and not to obstruct institutions implementing public …

Numbness Of The Ear Following Inferior Alveolar Nerve Block: The Forgotten Complication, W.C. Ngeow, W. L. Chai

Wei Cheong Ngeow

This article presents a distant complication in the auricle following the administration of a standard inferior alveolar nerve block. The patient experienced profound numbness of the auricle on the ipsilateral side of the injection that lasted for about an hour following unintended injection to the auriculotemporal nerve.

Craniofacial Anthropometric Norms Of Malaysian Indians, W.C. Ngeow, S. T. Aljunid

Wei Cheong Ngeow

Objective: This study was done to establish the craniofacial anthropometric norms of the young adult (18-25 years) Malaysian Indian. Materials and Methods: The study group consisted of convenient samples of 100 healthy volunteers, with equal number of female and male subjects who had no history of mixed racial-parentage. Twenty-two linear measurements were taken twice from 28 landmarks over six craniofacial regions. The methodology and evaluation of indices of the craniofacial region was adapted from Hajnis et al. Results: The minimum measurements are always contributed by the female Indian except for the nose height (n-sn), (left) eye fissure length (ex-en), upper …