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Full-Text Articles in Medicine and Health Sciences

A Comparative Study Of Steroid Hormone Levels And Oestrogen Receptor Alpha (Erα) Between Normal Bitch Uteri And Pyometra During Dioestrus, Sayamon Srisuwatanasagul, Kongkiat Srisuwatanasagul, Sudson Sirividayapong Jun 2006

A Comparative Study Of Steroid Hormone Levels And Oestrogen Receptor Alpha (Erα) Between Normal Bitch Uteri And Pyometra During Dioestrus, Sayamon Srisuwatanasagul, Kongkiat Srisuwatanasagul, Sudson Sirividayapong

The Thai Journal of Veterinary Medicine

Ovarian steroid hormones and their receptors play an important role in both physiological as well as pathological changes seen in the uterus. For the further understanding of the mechanism of pyometra, in relation to steroid hormones and their receptors in the bitch, the difference between the expression of the oestrogen receptor alpha (ERa) between normal and pyometra bitches during dioestrus was investigated. Uterine samples were collected during dioestrus from normal and pyometra bitches. Immunohistochemistry was used to investigate the expression of ERa in the different compartments of the uterus. The results showed that the levels of steroid hormones in the …


Computer Assisted Image Analysis Of Peroxidase Stained Endometrial Tissue, Ahmet Bariş Toprak, Seda Vatansever, Kemal Özbi̇lgi̇n Jan 2006

Computer Assisted Image Analysis Of Peroxidase Stained Endometrial Tissue, Ahmet Bariş Toprak, Seda Vatansever, Kemal Özbi̇lgi̇n

Turkish Journal of Medical Sciences

Aim: In immunohistochemistry, antibodies are used to detect and localize antigens in cellular compartments in sections taken from frozen or paraffin blocks. Currently, computerized image processing techniques are widely available to analyze immunohistochemically stained tissues; however, the image analysis programs are generally highly specific and expensive. We aimed to show the feasibility of computer assisted image analysis (CAIA) by using two computer programs currently in widespread use. Methods: Two available computer programs, Adobe Photoshop CS and ImageJ, were used to separate areas in the same tissue sections stained with NOS antibody and labeled with peroxidase in human endometrial tissue. CAIA …


Pathological And Immunohistochemical Investigation Of Naturally Occurring Systemic Candida Albicans Infection In Dogs, Recai̇ Tunca, Tolga Güvenç, Rifki Haziroğlu, Lale Ataseven, Hasan Özen, Ni̇hat Toplu Jan 2006

Pathological And Immunohistochemical Investigation Of Naturally Occurring Systemic Candida Albicans Infection In Dogs, Recai̇ Tunca, Tolga Güvenç, Rifki Haziroğlu, Lale Ataseven, Hasan Özen, Ni̇hat Toplu

Turkish Journal of Veterinary & Animal Sciences

Systemic candidiasis is a rare disease of animals. In this study, the clinical course, and cultural and pathological findings of systemic candidiasis are described and presumed predisposing factors are investigated in 3 dogs. Pathologically, pyogranulomatous lesions in various organs were present in all dogs. Blastospores, pseudohyphae, and true hyphae of Candida albicans were observed with periodic acid Schiff, Gomori's methenamine silver, and immunohistochemistry. Administrations of broad-spectrum antibiotics and corticosteroids and, in one dog, parvoviral infection were thought to be predisposing factors leading to opportunistic infection. The combined effect of immunosuppressants and antibiotics might have led to Candida colonization and dissemination …