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2005

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University of Tennessee, Knoxville

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Articles 1 - 15 of 15

Full-Text Articles in Medicine and Health Sciences

Disaster And Emergency Communications Prior To Computers/Internet: A Review, John W. Farnham Dec 2005

Disaster And Emergency Communications Prior To Computers/Internet: A Review, John W. Farnham

Faculty Publications and Other Works -- Nursing

When communications are needed the most desperately and most urgently, the difficulty of effecting the desired communications increases exponentially. Recent natural disasters in different parts of the world have provided eloquent testament to this. The history of disaster or emergency communications can provide us with a foundation for understanding the problems encountered today, and can offer us insight into how we might improve the systems and processes for communications. The first applications of communication technology that allowed messages to be sent more rapidly than the fastest form of transportation were mainly military in origin. This review takes us from the …


Expression Of G-Protein Inwardly Rectifying Potassium Channels (Girks) In Lung Cancer Cell Lines, Howard Plummer 3rd, Madhu Dhar, Maria Cekanova Ms, Rndr, Phd, Hildegard Schuller Aug 2005

Expression Of G-Protein Inwardly Rectifying Potassium Channels (Girks) In Lung Cancer Cell Lines, Howard Plummer 3rd, Madhu Dhar, Maria Cekanova Ms, Rndr, Phd, Hildegard Schuller

Faculty Publications and Other Works -- Biochemistry, Cellular and Molecular Biology

BACKGROUND: Previous data from our laboratory has indicated that there is a functional link between the beta-adrenergic receptor signaling pathway and the G-protein inwardly rectifying potassium channel (GIRK1) in human breast cancer cell lines. We wanted to determine if GIRK channels were expressed in lung cancers and if a similar link exists in lung cancer. METHODS: GIRK1-4 expression and levels were determined by reverse transcription polymerase chain reaction (RT-PCR) and real-time PCR. GIRK protein levels were determined by western blots and cell proliferation was determined by a 5-bromo-2'-deoxyuridine (BrdU) assay. RESULTS: GIRK1 mRNA was expressed in three of six small …


Expression Of G-Protein Inwardly Rectifying Potassium Channels (Girks) In Lung Cancer Cell Lines, Howard K. Plummer, Madhu S. Dhar, Maria Cekanova, Hildegard M. Schuller Aug 2005

Expression Of G-Protein Inwardly Rectifying Potassium Channels (Girks) In Lung Cancer Cell Lines, Howard K. Plummer, Madhu S. Dhar, Maria Cekanova, Hildegard M. Schuller

Faculty Publications and Other Works -- Large Animal Clinical Sciences

Background

Previous data from our laboratory has indicated that there is a functional link between the β-adrenergic receptor signaling pathway and the G-protein inwardly rectifying potassium channel (GIRK1) in human breast cancer cell lines. We wanted to determine if GIRK channels were expressed in lung cancers and if a similar link exists in lung cancer.

Methods

GIRK1-4 expression and levels were determined by reverse transcription polymerase chain reaction (RT-PCR) and real-time PCR. GIRK protein levels were determined by western blots and cell proliferation was determined by a 5-bromo-2'-deoxyuridine (BrdU) assay.

Results

GIRK1 mRNA was expressed in three of six small …


Inequalities In Neighbourhood Socioeconomic Characteristics: Potential Evidence-Base For Neighbourhood Health Planning., Agricola Odoi, R Wray, M Emo, S Birch, B Hutchison, J Eyles, T Abernathy Aug 2005

Inequalities In Neighbourhood Socioeconomic Characteristics: Potential Evidence-Base For Neighbourhood Health Planning., Agricola Odoi, R Wray, M Emo, S Birch, B Hutchison, J Eyles, T Abernathy

Faculty Publications and Other Works -- Biomedical and Diagnostic Sciences

BACKGROUND: Population health planning aims to improve the health of the entire population and to reduce health inequities among population groups. Socioeconomic factors are increasingly being recognized as major determinants of many aspects of health and causes of health inequities. Knowledge of socioeconomic characteristics of neighbourhoods is necessary to identify their unique health needs and enhance identification of socioeconomically disadvantaged populations. Careful integration of this knowledge into health planning activities is necessary to ensure that health planning and service provision are tailored to unique neighbourhood population health needs. In this study, we identify unique neighbourhood socioeconomic characteristics and classify the …


Expression Of The Α7 Nicotinic Acetylcholine Receptor In Human Lung Cells, Howard K. Plummer, Madhu Dhar, Hildegard M. Schuller Apr 2005

Expression Of The Α7 Nicotinic Acetylcholine Receptor In Human Lung Cells, Howard K. Plummer, Madhu Dhar, Hildegard M. Schuller

Faculty Publications and Other Works -- General Biology

Background

We and others have shown that one of the mechanisms of growth regulation of small cell lung cancer cell lines and cultured pulmonary neuroendocrine cells is by the binding of agonists to the α7 neuronal nicotinic acetylcholine receptor. In addition, we have shown that the nicotine-derived carcinogenic nitrosamine, 4(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), is a high affinity agonist for the α7 nicotinic acetylcholine receptor. In the present study, our goal was to determine the extent of α7 mRNA and protein expression in the human lung.

Methods

Experiments were done using reverse transcription polymerase chain reaction (RT-PCR), a nuclease protection assay and western …


Through The Lens Of Merleau-Ponty:Advancing The Phenomenological Approach To Nursing Research, Sandra Thomas Jan 2005

Through The Lens Of Merleau-Ponty:Advancing The Phenomenological Approach To Nursing Research, Sandra Thomas

Faculty Publications and Other Works -- Nursing

No abstract provided.


Patterns Of Risk Of Depressive Symptoms Among Hiv-Positive Women In The Southeastern United States, Linda Moneyham, Carolyn Murdaugh, Kenneth D. Phillips, Kirby Jackson, Abbas Tavakoli, Mary Boyd, Medha Vyavaharkar Jan 2005

Patterns Of Risk Of Depressive Symptoms Among Hiv-Positive Women In The Southeastern United States, Linda Moneyham, Carolyn Murdaugh, Kenneth D. Phillips, Kirby Jackson, Abbas Tavakoli, Mary Boyd, Medha Vyavaharkar

Faculty Publications and Other Works -- Nursing

Depressive symptoms are a common response to HIV disease, and women appear to be at particularly high risk. The authors report results from a crosssectional analysis of data collected from 280 rural women with HIV/AIDS in the Southeastern United States aimed at identifying risk factors of depressive symptoms. Stress theory provided a framework for identification of potential risk factors. Descriptive statistics, measures of association, and regression analyses were used to systematically identify patterns of risk. The final regression model included 22 factors that accounted for 69% of the variance in depressive symptoms. The majority of variance in depressive symptoms was …


An Exploration Of Problematic Interviewee Behaviors In Qualitative Research, M. Collins, M. Shattell, Sandra Thomas Jan 2005

An Exploration Of Problematic Interviewee Behaviors In Qualitative Research, M. Collins, M. Shattell, Sandra Thomas

Faculty Publications and Other Works -- Nursing

The interview is a staple of many qualitative approaches. Although textbooks offer extensive guidance to researchers about conducting interviews, less guidance is available about problematic interviewee behaviors, such as flattery or statements indicative of social desirability response bias. In this study, a secondary analysis of 22 phenomenological interview transcripts, we sought to examine problematic interviewee behaviors. More than 300 pages of typed text were subjected to line-by-line scrutiny, yielding only six potential instances of the phenomenon. Each could be interpreted several ways. What appeared to be flattery could also be perceived as simple gratitude or appreciation. We concluded that problematic …


Women's Anger, Agression, And Violence, Sandra Thomas Jan 2005

Women's Anger, Agression, And Violence, Sandra Thomas

Faculty Publications and Other Works -- Nursing

Themes of powerlessness, power, and paradox predominate in this reflection on more than 15 years of research on women's anger. Studies conducted in the United States, France, and Turkey are highlighted. These studies have negated several myths while illuminating the general rationality of women's anger: It is squarely grounded in interpersonal interactions in which people deny women power or resources, treat them unjustly, or behave irresponsibly toward them. The offenders are not strangers; rather they are their closest intimates. But few women learned healthy anger expression while growing up. Anger is a confusing and distressing emotion for women, intermingled with …


Stress Reduction As A Means To Enhance Oral Immunity In Hiv-Infected Individuals, Kenneth D. Phillips Jan 2005

Stress Reduction As A Means To Enhance Oral Immunity In Hiv-Infected Individuals, Kenneth D. Phillips

Faculty Publications and Other Works -- Nursing

No abstract provided.


Frontiers (3rd Quarter 2005) - Docs On A Mission; The Cyberknife; Alzheimer's Research, University Of Tennessee Medical Center, University Of Tennessee Graduate School Of Medicine Jan 2005

Frontiers (3rd Quarter 2005) - Docs On A Mission; The Cyberknife; Alzheimer's Research, University Of Tennessee Medical Center, University Of Tennessee Graduate School Of Medicine

Frontiers Magazine

No abstract provided.


Frontiers (4th Quarter 2005) - Working Together: Multidisciplinary Approach; Cancer Research; Becoming A Doctor, University Of Tennessee Medical Center, University Of Tennessee Graduate School Of Medicine Jan 2005

Frontiers (4th Quarter 2005) - Working Together: Multidisciplinary Approach; Cancer Research; Becoming A Doctor, University Of Tennessee Medical Center, University Of Tennessee Graduate School Of Medicine

Frontiers Magazine

No abstract provided.


Lack Of Antigen-Specific Tissue Remodeling In Mice Deficient In The Macrophage Galactose-Type Calcium-Type Lectin 1/Cd301a., Thandi M. Onami, K. Sato, Y. Imai, N. Higashi, Y. Kumamoto, S. M. Hedrick, T. Irimura Jan 2005

Lack Of Antigen-Specific Tissue Remodeling In Mice Deficient In The Macrophage Galactose-Type Calcium-Type Lectin 1/Cd301a., Thandi M. Onami, K. Sato, Y. Imai, N. Higashi, Y. Kumamoto, S. M. Hedrick, T. Irimura

Microbiology Publications and Other Works

Macrophage galactose-type C-type lectins (MGLs), which were recently named CD301, have 2 homologues in mice: MGL1 and MGL2. MGLs are expressed on macrophages and immature dendritic cells. The persistent presence of granulation tissue induced by a protein antigen was observed in wild-type mice but not in mice lacking an endogenous, macrophage-specific, galactose-type calcium-type lectin 1 (MGL1) in an air pouch model. The anti-MGL1 antibody suppressed the granulation tissue formation in wild-type mice. A large number of cells, present only in the pouch of MGL1-deficient mice, were not myeloid or lymphoid lineage cells and the number significantly declined after administration of …


Volume 3, Number 2 (2005), Ut Institute Of Agriculture Jan 2005

Volume 3, Number 2 (2005), Ut Institute Of Agriculture

Tennessee Land, Life and Science Magazine

Issue Highlights:

  • Crops that Boost Health
  • Army Service
  • UT's Bluegrass Club
  • UT Institute of Agriculture's Economic Impact


Volume 3, Number 1 (2005), Ut Institute Of Agriculture Jan 2005

Volume 3, Number 1 (2005), Ut Institute Of Agriculture

Tennessee Land, Life and Science Magazine

Issue Highlights:

  • Healing Waters
  • Partnerships that Build Community
  • Skills for Adult Success
  • UT Institute of Agriculture Outreach