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Articles 1 - 13 of 13
Full-Text Articles in Medicine and Health Sciences
Development And Assessment Of An Innovative Video To Introduce Concepts Of Adherence In Soweto, South Africa, Ilene Wong
Development And Assessment Of An Innovative Video To Introduce Concepts Of Adherence In Soweto, South Africa, Ilene Wong
Yale Medicine Thesis Digital Library
ISSUES: The widening availability of antiretroviral therapy but dearth of medication taking experience among rural South Africans has raised concerns about adequate adherence to these medications. Interventions to improve adherence have been limited in development and evaluation and are often not culturally appropriate to patients in resource poor settings. It is hypothesized that a culturally-sensitive audio-visual patient education program may be of significant use in increasing patient understanding of concepts of resistance and medication taking skills, particularly in areas with low literacy rates. METHODS: After focus groups with health care providers and HIV-positive adherence counselors, a 15 minute educational video …
Enteroviral Meningitis Surveillance In California, 2002-2004, Mary T. Chang
Enteroviral Meningitis Surveillance In California, 2002-2004, Mary T. Chang
Yale Medicine Thesis Digital Library
No abstract provided.
Activity-Dependent Modulation Of Neuronal Sodium Channel Expression, Joshua Peter Klein
Activity-Dependent Modulation Of Neuronal Sodium Channel Expression, Joshua Peter Klein
Yale Medicine Thesis Digital Library
No abstract provided.
Tuba, A Novel Protein Containing Bin/Amphiphysin/Rvs And Dbl Homology Domains, Links Dynamin To Regulation Of The Actin Cytoskeleton, Marco Antonio Del Valle Salazar
Tuba, A Novel Protein Containing Bin/Amphiphysin/Rvs And Dbl Homology Domains, Links Dynamin To Regulation Of The Actin Cytoskeleton, Marco Antonio Del Valle Salazar
Yale Medicine Thesis Digital Library
Tuba is a novel scaffold protein that functions to bring together dynamin with components of the actin cytoskeleton. It is concentrated at synapses in brain and binds dynamin selectively through four N-terminal Src homology-3 (SH3) domains. Tuba binds a variety of actin regulatory proteins, including N-WASP, CR16, WAVE1, WIRE, PIR121, NAP1, and Ena/VASP proteins, via a C-terminal SH3 domain. Direct binding partners include N-WASP and Ena/VASP proteins. Forced targeting of the C-terminal SH3 domain to the mitochondrial surface can promote accumulation of F-actin around mitochondria. A Dbl homology domain present in the middle of Tuba upstream of a Bin/amphiphysin/Rvs (BAR) …
Mechanistic And Structure-Function Analysis Of Thymidylate Synthase-Dihydrofolate Reductase From Protozoal Parasites: Implications For The Development Of Non-Active Site Inhibitors, Chloé E. Atreya
Yale Medicine Thesis Digital Library
A major advance in the field of bifunctional thymidylate synthase-dihydrofolate reductase (TS-DHFR) is the recent crystallization of two apicomplexan TS-DHFR enzymes, from Cryptosporidium hominis and Plasmodium falciparum, which demonstrate significant structural differences from the well-known kinetoplastid TS-DHFR structure (Leishmania major ). A principal finding of this dissertation research is that the significant structural differences between the apicomplexa and kinetoplastid bifunctional TS-DHFR enzymes translate as significant mechanistic differences between parasite classes and among parasites within the same class.An in depth mechanistic analysis of C. hominis TS-DHFR and a preliminary analysis of the P. falciparum enzyme were completed. Results with C. hominis …
Knowledge Of Hiv/Aids And Attitudes About Condom Use Among Nigerian University Students, Ugonna Ada Duru
Knowledge Of Hiv/Aids And Attitudes About Condom Use Among Nigerian University Students, Ugonna Ada Duru
Yale Medicine Thesis Digital Library
No abstract provided.
Thinking Beyond Health To Motivate Dietary Change: Piloting A Vegan Healthy Eating Program For Obesity Management, Mark Alan Berman
Thinking Beyond Health To Motivate Dietary Change: Piloting A Vegan Healthy Eating Program For Obesity Management, Mark Alan Berman
Yale Medicine Thesis Digital Library
This pilot study assessed the feasibility, acceptability and efficacy of a novel approach to facilitating dietary change and weight loss in obese adults by presenting vegan environmental, health and farm animal treatment information in a 6 week, group-based, educational nutrition program (called a vegan healthy eating program). Twenty-nine (29) medically stable, obese adults were recruited from 3 ambulatory care clinics at UCSF and enrolled using partial randomization into one of two serially occurring intervention groups (Group 1 n=14, followed by Group 2 n=15). A delayed intervention control group (n=9) was used, consisting of participants enrolled in Group 2 who were …
Alcohol And Injury: An Analysis Of At Risk Drinkers Presenting To The Yale-New Haven Hospital Emergency Room, Hilary Furste Ryder
Alcohol And Injury: An Analysis Of At Risk Drinkers Presenting To The Yale-New Haven Hospital Emergency Room, Hilary Furste Ryder
Yale Medicine Thesis Digital Library
Compared with the population at-large, the Emergency Department (ED) population sees a high percentage of people with alcohol use and abuse problems. Therefore, the ED is well suited for the implementation of alcohol screening and interventions. It is important to be able to identify at risk drinkers who come to the ED for treatment for injury or other medical problems so that interventions may occur. Project ED Health conducted intensive interviews with harmful and hazardous drinkers presenting to the ED for treatment of injury or medical problem. The data was entered into a database and analyzed to find differences between …
Patient Age, Number And Type Of Clinical Encounters, And Provider Advice To Quit Smoking. Brfss 2000, Sean C. Lucan
Patient Age, Number And Type Of Clinical Encounters, And Provider Advice To Quit Smoking. Brfss 2000, Sean C. Lucan
Yale Medicine Thesis Digital Library
The purpose of this study was to determine how often smoking patients receive quit advice and if patient age, and number and type of clinical encounters are associated with odds of receipt. Behavioral Risk Factor Surveillance System (BRFSS) 2000 data were used to study 10,582 smokers (aged ≥ 18) having ≥ 1 of three types of clinical encounters in the past year: routine checkups, other physician encounters, or dental visits. Multivariate-adjusted odds ratios (ORs) for quit advice by patient age, encounter type, and number of doctor's visits were calculated. Almost 55% of patients were advised to quit smoking. There was …
Birth Weight As A Risk Factor For Autism Spectrum Disorders : A Pilot Study And Case-Control Study, Virginia Grace Cohen
Birth Weight As A Risk Factor For Autism Spectrum Disorders : A Pilot Study And Case-Control Study, Virginia Grace Cohen
Yale Medicine Thesis Digital Library
No abstract provided.
Co-Localization Of Β1,6-Branched Oligosaccharides And Coarse Melanin In Macrophage-Melanoma Fusion Hybrids And Human Melanoma Cells In Vitro, Reena N. Rupani
Co-Localization Of Β1,6-Branched Oligosaccharides And Coarse Melanin In Macrophage-Melanoma Fusion Hybrids And Human Melanoma Cells In Vitro, Reena N. Rupani
Yale Medicine Thesis Digital Library
No abstract provided.
Knowledge And Attitudes Of Healthcare Providers Towards Prenatal Hiv Screening And Prevention Of Mother-To-Child Transmission In Nigeria, Laura Nneka Mobisson
Knowledge And Attitudes Of Healthcare Providers Towards Prenatal Hiv Screening And Prevention Of Mother-To-Child Transmission In Nigeria, Laura Nneka Mobisson
Yale Medicine Thesis Digital Library
No abstract provided.
Developing A Scale To Measure Just About Anything: Comparisons Across Groups And Individuals, Katharine Fast
Developing A Scale To Measure Just About Anything: Comparisons Across Groups And Individuals, Katharine Fast
Yale Medicine Thesis Digital Library
No abstract provided.