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Full-Text Articles in Medicine and Health Sciences
The Role Of Osteopontin In Vascular Remodeling, Daniel Myers
The Role Of Osteopontin In Vascular Remodeling, Daniel Myers
Electronic Theses and Dissertations
Chronic obstructive vascular disease is a major contributor to mortality in developed nations. The pathology typically involves neointima formation accompanied by vascular remodeling in the presence of inflammation. The disease can be modeled in animals with the response to a direct injury of the vasculature. This text describes a project examining the role of osteopontin (OPN) in vascular remodeling. The projectis goal was to mechanistically describe the contribution of OPN to the vascular injury response. The hypothesis that the presence of OPN affects the formation of neointima and constrictive remodeling associated with vascular injury was addressed using the strategy of …
Estimation Of Standardized Mortality Ratio In Geographic Epidemiology, Anna Kettermann
Estimation Of Standardized Mortality Ratio In Geographic Epidemiology, Anna Kettermann
Electronic Theses and Dissertations
The analysis of geographic variation of disease and its representation on a map form an important topic of research in epidemiology and in public health in general. Identification of spatial heterogeneity of relative risk using morbidity and mortality data is required. The usual technique of disease atlas generation consists of data collection (observed number of disease cases). These data are collected during a continuous period of time (5 to 10 years). The second aspect of atlas creation relates to the analysis of these data. A traditional measure of the spatial variation is usually taken as a ratio of the number …