Medicine and Health Sciences Commons^™

Sex Differences In Copd And Lung Cancer Mortality Trends—United States, 1968–1999, Neely Kazerouni, C. J. Alverson, Stephen C. Redd, Joshua A. Mott, David M. Mannino

David M. Mannino

Purpose: Cigarette smoking by U.S. women in the 1940s and 1950s caused large increases in smoking-related lung disease among women. To determine the magnitude of these increases, we compared the mortality trends for males and females in the United States for chronic obstructive pulmonary disease (COPD) and lung cancer for 1968-1999.

Methods: We used the national mortality data files compiled by the National Center for Health Statistics of the CDC and U.S. census data to calculate age-adjusted (2000) death rates for COPD, lung cancer, and all causes.

Results: COPD death rate for females increased by 382% from 1968 through 1999, …

Risk Factors For Asthma Incidence: A Review Of Recent Prospective Evidence, M. S. King, David M. Mannino, F. Holguin

David M. Mannino

AIM:

The aim of this study is to determine what factors have been shown, in prospective studies, to predict the incidence of asthma.

METHODS:

We performed a systematic review of peer-reviewed literature from 1994 to 2004 to determine what factors predict the development of asthma in both children and adults. This search strategy yielded 40 studies, with 36 providing some estimate of asthma incidence for the total sample and or a specific subgroup.

RESULTS:

Annual estimated incidence of physician-diagnosed asthma ranged from 0.6 to 29.5 per 1000 persons. Risk factors for incident asthma among children included: male sex, atopic sensitization, …

Copd In The Never-Smoker, David M. Mannino, Kathryn Marie Mcgonigle

David M. Mannino

Objectives 1. Identify never-smokers as an important subset of the COPD population. 2. Discuss the relationship between asthma and COPD. 3. Understand the genetic components of COPD. 4. Identify occupational risk factors for COPD. 5. Discuss prevention methods for COPD in the never-smoker.