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Full-Text Articles in Medicine and Health Sciences

The Effect Of Moderate +Gz Force On The Cervical Spine Bone Mineral Density In Raaf Pc-9 Pilots, Meghan C. Grant Jan 2001

The Effect Of Moderate +Gz Force On The Cervical Spine Bone Mineral Density In Raaf Pc-9 Pilots, Meghan C. Grant

Theses : Honours

Previous research on exercise and bone mineral density (BMD) has established that increases in BMD are site specific, responding to unusual strain and particularly to high magnitude loading. The positive Gz forces generated during high performance flying provide all three variables. Naumann, Bennell and Wark (2000) investigated the effects of moderate gravitational force on the BMD of fighter pilots. The pilots in this study had significant increases in BMD and bone mineral content (BMC) for the thoracic spine, pelvis and total body. However, it is now suspected that the cervical spine, which was unable to be analysed at that time …


Molecular Genetic Investigation Of Autosomal Dominant Muscular Dystrophy, Christopher Meredith Jan 2001

Molecular Genetic Investigation Of Autosomal Dominant Muscular Dystrophy, Christopher Meredith

Theses: Doctorates and Masters

This thesis contributes to the Human Genome Project by adding detail to the physical and genetic maps of the human genome, and by identifying a strong candidate gene for a form of distal myopathy. Genomic clones for the human skeletal muscle genes slow troponin (TNN/1), alpha actin (ACTA1), and (3-tropomyosin (TPM2) were isolated for use in the fluorescent in situ hybridisation localisation of these genes on the cytogenetic map of the human genome. The localisation of these genes made them potential candidates for inherited skeletal muscle diseases, including the muscular dystrophies investigated here. Microsatellite, VNTR and RFLP markers were used …


Genetic Variation And Disease In The Roma (Gypsies), David J. Gresham Jan 2001

Genetic Variation And Disease In The Roma (Gypsies), David J. Gresham

Theses: Doctorates and Masters

The Roma (Gypsies) are a European people composed of a mosaic of culturally heterogeneous populations. Linguistic analyses point to their origins in the Indian subcontinent. Cultural diversity in extant Romani populations suggests that they are descended from a mixture of Indian populations. Previous population genetic studies of the Roma have supported this claim by demonstrating the genetic heterogeneity of Romani populations. More recently, medical genetic research has detected identical founder mutations in separated Romani populations, which provides evidence of their relatedness. In this thesis, the genetic heritage of the Roma and its significance for genetic disease and research is investigated. …