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Full-Text Articles in Medicine and Health Sciences
The Effects Of Smoking On Glutathione Levels Inbronchoalveolar Lavage Fluid, Füsun Alataş, Necla Özdemi̇r, Özkan Alataş, Si̇nan Ergi̇nel, Muzaffer Meti̇ntaş, Rana Işik
The Effects Of Smoking On Glutathione Levels Inbronchoalveolar Lavage Fluid, Füsun Alataş, Necla Özdemi̇r, Özkan Alataş, Si̇nan Ergi̇nel, Muzaffer Meti̇ntaş, Rana Işik
Turkish Journal of Medical Sciences
Cigarette smoke contains high concentrations of oxidants and reactive oxygen species. The aim of this study was to evaluate the effect of long-term cigarette smoking on glutathione (GSH) levels in bronchoalveolar lavage (BAL) fluid. Nineteen current cigarette smokers and seven healthy nonsmoking volunteers were included in the study. BAL was performed by infusion of five sequential 20 ml aliquots and each aliquot was immediately aspirated. The levels of GSH were determined in BAL fluids. The epithelial lining fluid volume was calculated by the ratio of urea concentration in BAL fluid to that in serum. Lower GSH levels were observed in …
Oxidative Damage In Erythrocytes During Cold Storage With Organ Preservation Solution, Aki̇f B. Memmedoğlu, Ahmet Özaydin, İsmai̇l Seçki̇n, Gönül Sultuybek
Oxidative Damage In Erythrocytes During Cold Storage With Organ Preservation Solution, Aki̇f B. Memmedoğlu, Ahmet Özaydin, İsmai̇l Seçki̇n, Gönül Sultuybek
Turkish Journal of Medical Sciences
It is known that erythrocyte aggregation in renal tissue during preserva-tion is cause of microcirculation defects in the reperfusion period. The aim of our study is to investigate oxidative damage in erythrocytes relative to the time of cold ischemia during organ preservation and relationship between lipid peroxidation and development of these damages. In experiments with a rabbit model, explanted kidneys were exposed to perfusion and 96 hours preservation with Euro-Collins (EC) in the 1st group, and University of Wisconsin (UW) solution in the 2nd group. Electron-microscopic examinations in renal tissueswere performed. Lipid peroxidation and glutathione levels in erythrocytes preserved in …