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Full-Text Articles in Medicine and Health Sciences
Uwomj Volume 69, No 2, Spring 1999, Western University
Uwomj Volume 69, No 2, Spring 1999, Western University
University of Western Ontario Medical Journal
An interdisciplinary medical science publication; established 1930.
A Review Of The Anticoagulant Pesticide Pindone, Laurie E. Twigg, Tim J. Lowe, Gary R. Martin, Garry S. Gray
A Review Of The Anticoagulant Pesticide Pindone, Laurie E. Twigg, Tim J. Lowe, Gary R. Martin, Garry S. Gray
Books & book chapters
A review of the use of pindone for rabbit control in Western Australia is timely due to increased public concern over the use of this toxin, and because non-target deaths of some native Australian animals have been known to occur following its use. Pindone is one of the first generation indandione anticoagulant rodenticides which were developed in the late 1940' s. The toxicity of anticoagulants arises from their inhibition of vitamin K-dependent clotting factors in the blood. Thus therapeutic administration of vitamin K provides a reliable antidote against anticoagulant poisoning. Pindone is slow acting and works best with repeated small …