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Full-Text Articles in Medicine and Health Sciences
Mannoprotein Adhesin Of Candida Albicansgerm Tubes, Gülhan Vardar-Ünlü
Mannoprotein Adhesin Of Candida Albicansgerm Tubes, Gülhan Vardar-Ünlü
Turkish Journal of Medical Sciences
The production and detection of a mannoprotein adhesin (MPA) of the hyphal-form cells of C. albicans on plastic petri dishes was investigated. Using Concanavalin A-coated latex microspheres, the MPA was detected on the plastic surface on which C. albicans produced germ tubes. The adhesin was extracted using dithiothreitol and iodoacetamide. It did not inhibit the adhesion of the yeast-form C. albicans to buccal epithelial cells (BEC). This suggested that the MPA of the hyphal-form cells on the plastic was different from that on the yeast cells responsible for attachment to the BECs.
Identification Of Fibronectin Adhesins On Candidaalbicans, Gülhan Vardar-Ünlü
Identification Of Fibronectin Adhesins On Candidaalbicans, Gülhan Vardar-Ünlü
Turkish Journal of Medical Sciences
The pattern of distribution of fibronectin adhesins on yeast and hyphal-form Candida albicanswas studied with gold-labelled fibronectin and transmission electron microscopy. The germ-tube parts of the hyphal-form cells were the major binding sites for gold-labelled fibronectin, and the attached yeast-cell parts and yeast-form cell remained unlabelled. Therefore, the walls of the germ tube parts of hyphal-form cells might be sites of important interactions between C. albicans and host tissues containing fibronectin.