Medicine and Health Sciences Commons^™

The Placebo Effect, Charles Weijer

Charles Weijer

No abstract provided.

Do Patients With Breast Cancer Participating In Clinical Trials Receive Better Nursing Care?, Myriam Skrutkowska, Charles Weijer

Charles Weijer

PURPOSE/OBJECTIVES: To examine differences in nursing care received by patients with breast cancer enrolled in clinical trials and those not enrolled in clinical trials.

DESIGN: Retrospective review of clinic charts.

SETTING: Oncology outpatient department of a tertiary-care hospital. SAMPLE: 90 women with early stage breast cancer. The mean age of the women was 53 years. More than half of the women (51 of 90) were treated in a clinical trial.

METHODS: Retrospective chart review of all the nurse-patient clinic encounters for a six-month period from date of cancer diagnosis. The content of each encounter was coded using a modified version …

Duty And Healing: The Lifework Of Benjamin Freedman, Charles Weijer

Charles Weijer

BENJAMIN FREEDMAN, un des plus grands bioéthiciens du Canada et universitaire re- connu sur la scène internationale, est mort le 20 mars 1997. Professeur de médecine à l’Université McGill de Montréal, Freedman a beaucoup contribué au domaine de la bioéthique, où il a fait notamment des travaux fondamentaux sur le consentement éclairé et la compétence. Dans le domaine de l’éthique de la recherche, Freedman est l’auteur du concept de l’équivalence clinique comme condition préalable à l’exécution éthique de recherches cliniques. Des travaux subséquents ont clarifié l’analyse éthique du risque et les limites du risque permis- sible en recherche sur les …

Spilker's Guide To Clinical Trials On Cd-Rom, Charles Weijer

Charles Weijer

No abstract provided.

Remembering Benjamin Freedman (1951-1997), Françoise Baylis, Charles Weijer

Charles Weijer

No abstract provided.

Selecting Subjects For Participation In Clinical Research: An Empirical Inquiry And Ethical Analysis, Charles Weijer

Charles Weijer

Procedures for the selection of subjects for participation in randomized clinical trials--usually formalized as eligibility criteria in the study protocol--have both scientific and ethical implications. In this thesis, I undertake an examination of eligibility criteria at three stages in the genesis and dissemination of medical knowledge: clinical trial protocol, interpretation by investigators, and reporting of study results.

In the first chapter, ethical issues in subject selection are reviewed and the main study questions are presented. In the second chapter, the results of an examination of eligibility criteria in two sets of clinical trials, one sponsored by the NSABP, the other …

The Human Radiation Experiments: Final Report Of The Advisory Committee On Human Radiation Experiments, Charles Weijer

Charles Weijer

No abstract provided.

Bioethics For Clinicians: 10. Research Ethics, Charles Weijer, Bernard Dickens, Eric Meslin

Charles Weijer

Medical research involving human subjects raises complex ethical, legal and social issues. Investigators sometimes find that their obligations with respect to a research project come into conflict with their obligations to individual patients. The ethical conduct of research rests on 3 guiding principles: respect for persons, beneficience, and justice. Respect for persons underlies the duty to obtain informed consent from study participants. Beneficence demands a favourable balance between the potential benefits and harms of participation. Justice requires that vulnerable people not be exploited and that eligible candidates who may benefit from participation not be excluded without good cause. Studies must …

Full House: The Spread Of Excellence From Plato To Darwin, Charles Weijer

Charles Weijer

No abstract provided.

Film And Narrative In Bioethics: Akira Kurosawa's Ikiru, Charles Weijer

Charles Weijer

No abstract provided.