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Full-Text Articles in Medicine and Health Sciences

Bone Absorptiometry In Metabolic Bone Disease: Baseline Values And Long-Term Treatment With Calcitriol (Post-Menopausal Osteoporosis Versus Osteomalacia), A. Caniggia, B. Frediani Jan 1995

Bone Absorptiometry In Metabolic Bone Disease: Baseline Values And Long-Term Treatment With Calcitriol (Post-Menopausal Osteoporosis Versus Osteomalacia), A. Caniggia, B. Frediani

Cells and Materials

Total body bone absorptiometry reveals low mineral density in both postmenopausal osteoporosis and osteomalacia patients. The method was used to investigate the effect of calcitriol administration on patients suffering from one of these conditions. In osteomalacia, the administration of calcitriol resulted in a dramatic improvement in bone mineral density (sometimes up to 50% in 12 months), indicating the rapid mineralization of previously uncalcified bone tissue as a result of the normalization of the Ca x P product. In osteoporosis a similar treatment was seen to halt the progressive decrease in bone mineral levels and sometimes resulted in minor increases in …


Room Temperature Aging Of Pd-Cu-Ga Dental Alloys, William A. Brantley, Zhuo Cai, Qiang Wu, Alan B. Carr, John C. Mitchell Jan 1995

Room Temperature Aging Of Pd-Cu-Ga Dental Alloys, William A. Brantley, Zhuo Cai, Qiang Wu, Alan B. Carr, John C. Mitchell

Cells and Materials

Specimens of three Pd-Cu-Ga dental alloys cast five years ago and subsequently stored at room temperature were reexamined and observed to have lower amounts of the eutectic constituents in the near-surface region than originally present, along with other microstructural changes. This previously unreported room temperature aging behavior of these alloys is attributed to the presence of high-diffusivity paths in the non-equilibrium ascast eutectic structures and to the essential role of the surface for the vacancy diffusion mechanism. These results may have important clinical significance for the ill vivo corrosion resistance and long-term biocompatibility of the Pd-Cu-Ga alloys.


Some Observations On The Structure Of Encrusting Biofilms Of Proteus Mirabilis On Urethral Catheters, C. Winters, D. J. Stickler, N. S. Howe, T. J. Williams, N. Wilkinson, C. J. Buckley Jan 1995

Some Observations On The Structure Of Encrusting Biofilms Of Proteus Mirabilis On Urethral Catheters, C. Winters, D. J. Stickler, N. S. Howe, T. J. Williams, N. Wilkinson, C. J. Buckley

Cells and Materials

A physical model of the bladder has been used to study the process of urinary catheter encrustation. Techniques have been devised for the preparation of sections through these encrustations in situ on the luminal surfaces of catheters and for mapping the distribution of calcium and magnesium in the biofilms. Transmission electron microscopy on these sections showed struvite-like crystals lying in the matrix and in direct contact with the catheter surface. Calcium phosphate ("bioapatite") was distributed throughout the film and many of these amorphous particles appear to have cells at their cores. Freeze-substituted sections of biofilms also showed electron dense materials …


Optical Bone Chambers As Tools For Studying The Bone-Implant Interface: A Review, Howard Winet Jan 1995

Optical Bone Chambers As Tools For Studying The Bone-Implant Interface: A Review, Howard Winet

Cells and Materials

Bone chamber intravital microscopy combines the control volume of in vitro models and the chemical complexity of in vivo models to optimize the study of bone physiology in situ. As an optical tool it provides a window to dynamic events at the tissue level of magnification. In particular, it allows measures of microvascular events: (1) in space by magnifying local perfused vasculature and microcirculation at any instant, and (2) in time by providing the same volume of tissue for weekly viewing of an evolving process such as bone healing. This quartz-bearing titanium screw has revealed a consistent order for …