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1986

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Arylsulfatase B Activity In Cultured Retinal Pigment Epithelium: Regional Studies In Feline Mucopolysaccharidosis Vi., Lawrence E. Stramm, R J. Desnick, M Haskins, Gustavo D. Aguirre Jun 1986

Arylsulfatase B Activity In Cultured Retinal Pigment Epithelium: Regional Studies In Feline Mucopolysaccharidosis Vi., Lawrence E. Stramm, R J. Desnick, M Haskins, Gustavo D. Aguirre

Gustavo D. Aguirre, VMD, PhD

Feline mucopolysaccharidosis VI (MPS VI) is a recessively inherited lysosomal storage disease resulting from a deficiency of arylsulfatase B (ASB). Previous histopathologic findings have indicated that the disease is expressed morphologically in non-pigmented retinal pigment epithelial cells (RPE) in the posterior pole and superior equatorial regions by the accumulation of vacuolated inclusions and eventual cellular hypertrophy, while pigmented regions in the periphery are minimally affected. To determine if the regional and age-dependent variations in disease severity result from differences in residual enzyme activity, primary cultures of feline MPS VI-affected RPE were initiated from defined regions of the eye and maintained …

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The Relationship Of Nursing Work Environment To Empowerment, Genevieve Chandler Dec 1985

The Relationship Of Nursing Work Environment To Empowerment, Genevieve Chandler

Genevieve E. Chandler

This is an exploratory study of nurses' (~= 268) perceptions of work conditions. The theoretical framework was developed from Rogers' nursing model and Kanter's organizational theory. The principle of integrality from Rogers' nursing model was utilized. Integrality predicts changes in life process through the interaction of the individual and environment. Kanter's theory is more specific to the work areas with similar assumptions to Rogers specifically: The interaction between the individual and the work environment produces work behaviors. The sample was from two hospitals of similar size, purpose, and location in northeast Utah. The nurses were informed of the study through …

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