Medicine and Health Sciences Commons^™

Role Of Human Protein Disulfide Isomerase (Pdi) In The Redox Regulation Of Anthrax Receptor 2 (Antxr2), Naima Mohamed Alshrif

Open Access Theses & Dissertations

Anthrax is an acute infectious disease caused by B. anthracis, a gram-positive and spore-forming bacterium. Anthrax toxin is a tripartite AB toxin composed of a receptor binding/pore-forming moiety, protective antigen (PA), and two catalytic moieties, edema factor (EF) and lethal factor (LF). Anthrax toxin PA binds to cell-surface receptors, where it gets activated by furin, and assembles into a ring-like heptameric structure. The toxin-receptor complex is internalized into endosomes where the acidic pH triggers PA pore formation on the endosomal membrane that translocates the toxin catalytic moieties. Recent study has shown that anthrax toxin receptors play a critical role in …

The Impact Of Literacy Through Movement In A 3rd Grade Hispanic Classroom, Daniel Peregrino

Open Access Theses & Dissertations

This case study examines the effects of a kinesthetic literacy-training program on the complexity of narrative production and performance on the Garfield Motivation to Read Survey in a group of four 3rd grade elementary students. The 3rd grade teacher attended a Literacy Through Movement workshop to learn a range of movement-based literacy activities and methods for the classroom. The LITMO program was then implemented as part of a language arts poetry module for 3 weeks in her classroom. Changes in four students' performance on the Garfield Survey and narrative samples were measured before and after the LITMO intervention. Results suggest …

"The Strictest Smoking Ban In The Nation": A Retrospective Case Study Of The Political Factors That Facilitated And Inhibited The Passage Of El Paso's Clean Indoor Air Ordinance, Xochiquetzalli Gamboa

Open Access Theses & Dissertations

The purpose of this report is to describe, using archival print media sources, the factors that influenced the passage of the controversial El Paso Clean Indoor Air Ordinance in 2001. Although public health professionals had had more than 50 years of evidence proving the dangers of tobacco consumption, very few municipalities were concerned with implementing bans of any type on indoor smoking in public places ten years ago.

El Paso, TX, made national history when it introduced and approved what was then called "the strictest smoking ban in the nation" (Falgoust, 2004). How was such a progressive measure enacted in …

Pre, Peri, And Post-Migration Perspectives Of Mexican National Refugees Related To Experiences Of Violence, Migration, And Resettlement Along The Texas-Mexico Border, Jana L. Mccallister

Open Access Theses & Dissertations

For the past six years, the war on drugs in Mexico has resulted in the out-migration of tens of thousands of Mexican nationals fleeing violence, many settling in El Paso, Texas. The historical context of being pulled to the U.S. for economic opportunity had changed. Mexican nationals were now refugees pushed out of their country for safety. Because the context of migration had changed, the close proximity and similarities between El Paso, Texas and Ciudad Juárez, and the availability of social support in the U.S., the experiences of this refugee cohort were unique. Because increasing numbers were seeking mental health …

Comparison Of Performance Between Elderly Individuals And Collegiate Athletes On The Immediate Post-Assessment And Cognitive Test, Kevin Van Den Bogaard

Open Access Theses & Dissertations

Preventing falls in the elderly population requires a collaborative effort that includes medical treatment, rehabilitation, and environmental modification. Medical assessment of the elderly after a fall is designed to treat the potential conditions associated with the fall, such as broken limbs and trauma to the head resulting in a mild traumatic brain injury (mTBI). Currently, there is no standardized test or protocol accepted across health care facilities to track the cognitive-communicative recovery of elderly patients. A group of elderly individuals deemed healthy and capable of independent living were administered the baseline Immediate Post Assessment and Cognitive Test (ImPACT). This study …

Impact Of Nutrition Education In High School Students, Leticia Cortez

Open Access Theses & Dissertations

The diet of adolescents is typically high in calories, fat, and saturated fat and often fails to meet the daily recommended amounts of fruits, vegetables, and calcium-rich foods. The frequent consumption of unhealthy diets in combination with the lack of physical activity has resulted in a high prevalence of obesity worldwide. Approximately 17% of adolescents in the United States are obese. Obesity is a common risk factor for the development of chronic disease such as heart disease and diabetes. In the last few decades and along with a high prevalence of obesity there has also been an increased prevalence of …

Mobilizing Subdominant Hiv-Specific Ctls As A Novel Vaccine Strategy, Margaret Christina Costanzo

Open Access Theses & Dissertations

To overcome the extreme antigenic diversity of HIV, there is increasing interest in developing vaccines that target CD8 T cell responses to conserved regions of the viral proteome. Understanding the immunogenic potential of these domains is therefore critical for the success of this vaccine strategy. CD8 T cell responses to conserved domains restricted by the "neutral" and highly prevalent HLA-A2 allele have not been extensively characterized. Here we describe a novel essentially invariant 10-mer epitope in HIV Gag (p2414-23, RTLNAWVKVV (RV10)) in that it is expressed by the majority HIV isolates from all clades. Here we examined the character of …

Coping As A Mediator Between Proximity To Violence In Juarez, And Ptsd Symptoms Among College Students Attending A University On The Texas - Mexico Border, Francis Javier Reyes

Open Access Theses & Dissertations

The present study directly examined whether proximity to ongoing violence might lead to symptoms of Post-Traumatic Stress Disorder (PTSD) in a sample of students attending a border university less than a mile from the US Mexico border. Exposure to violence is a common cause of PTSD symptomology. Prior research in the region suggests that ongoing traumatic stress due to the violence in Juarez is associated with increased PTSD symptomology. Because coping skills are thought to protect individuals from PTSD the Transactional Model of Stress and Coping (Lazarus & Folkman, 1984) guided the study. The purpose of this study was to …

Ethnicity And Gender As Predictors Of Physical Activity And Social Cognitive Determinants, Amber Luana Bridges-Arzaga

Open Access Theses & Dissertations

The purpose of this study was to examine ethnicity and gender as predictors of physical activity (PA) and the Social Cognitive Theory (SCT) constructs related to physical activity among college students. Specifically, the study examined differences in PA between Hispanic college students and their non-Hispanic White counterparts. The study also examined differences between Hispanic and non-Hispanic White participants in SCT constructs regarding PA, such as social support, self-efficacy, outcome expectancies, and self-regulation. Additionally, the study assessed differences between male and female college students in relation to PA and SCT constructs. Finally, the study explored meditational effects of SCT constructs on …

Brain Maturation In The Adolescent Athlete And It's Implication On Concussion Management, Jacqueline Picone

Open Access Theses & Dissertations

As the adolescent brain develops, any event that interrupts the process, such as a concussion, may result in long-term academic and social effects (Dennis & Levin, 2004). To date, there is no specific assessment or protocol published that consider the cognitive and development of the adolescent brain when managing concussion (Patel, et al., 2005). Purpose: to investigate whether there is a statistically significant difference between the composite scores and sub-test scores in the subtests on the ImPACT battery: Word Memory, Design Memory, X's and O's, Symbol Match, Color Match, and Three Letters, of high school male athletes between the ages …

Phonological Memory Associations Of Language Impairment In Bilingual Children, Marcela Susa

Open Access Theses & Dissertations

Knowledge-based assessments of language impairments have been found to contain bias for assessing performance in bilingual children from diverse cultural backgrounds. As an alternative, measures related to performance of phonological working memory are becoming more popular for bilingual children. The purpose of the current study was to investigate how bilingual children with language impairment (BILI) would perform on nonword repetition and sentence repetition when compared to typically developing peers (BITD). Also, the current study investigated the extent to which the nonword repetition task and sentence repetition task were associated with each other in bilingual (English-Spanish) children. Results demonstrated that typically …

Constrained Optimal Control For A Multi-Group Discrete Time Influenza Model, Paula Andrea Gonzalez Parra

Open Access Theses & Dissertations

During the last decades, mathematical epidemiological models have been used to understand the dynamics of infectious diseases and guide public health policy. In particular, several continuous models have been considered to study single in uenza outbreaks and the impact of dierent control policies. In this dissertation, a discrete time model is introduced in order to study optimal control strategies for in uenza transmission; since epidemiological data is collected on discrete units of time, a discrete formulation is more ecient. From a mathematical point of view, continuous time model are easier to analyze, however, the numerical solution of discrete-time models is …

Evaluation Of Protection Induced By Dna Vaccine Candidate Against Leishmania Mexicana In Balb/C Mice Model, Rosina Rodarte

Open Access Theses & Dissertations

Background and Significance. The leishmaniases are a diverse group of diseases with four major clinical manifestations: cutaneous, mucocutaneous, visceral, and diffuse. Approximately 21 Leishmania species and 30 sandfly vectors have been implicated in human leishmaniasis. Leishmaniasis is endemic in 88 countries, 72 are developing countries. Currently, 350 million people live in leishmaniasis-endemic areas around the world. The true incidence of the disease is not known. However, the estimated incidence for visceral leishmaniasis is 500,000 cases per year, and for cutaneous and mucocutaneous leishmaniasis 1.5-2 million cases per year. Visceral leishmaniasis causes 70,000 deaths each year. In the Americas region, …

Post-Traumatic Stress Symptoms And Alcohol-Related Outcomes Among Municipal Firefighters: Exploring The Mediational Role Of Drinking Motives And Maladaptive Coping Strategies, Anabel Cardiel

Open Access Theses & Dissertations

Due to the frequent exposure to traumatic events, the firefighting profession places firefighters at high risk for PTSD symptoms (Berger et al., 2011). Consequently, those experiencing PTSD symptoms are inclined to consume alcohol to cope with related symptoms or to alleviate psychological distress. Two theories that guided this study are the Stress and Coping Theory (Lazarus & Folkman, 1984), and the Self-Medication Hypothesis (Khantzian, 1985). The main purpose of this study was to examine the relationship between PTSD symptoms and alcohol-related outcomes including At-Risk Drinking, Alcohol-Related Outcomes and Alcohol Consumption, in a population of El Paso firefighters (n = 740). …

Correlates Of Marijuana Use In A Hispanic College Sample, Joseph Ephraim Charter

Open Access Theses & Dissertations

Currently there is a dearth of literature regarding marijuana and its correlates of use, particularly in Hispanics. Marijuana is the most widely used illicit drug, and its use has increased in recent years. This study aimed to assess correlates of marijuana use in a Hispanic college student sample. Data were collected from 549 participants from University psychology courses. Participants completed a comprehensive survey packet consisting of: demographics, marijuana use history, tobacco and alcohol use, depression, anxiety, stress, and acculturation. Descriptive analyses were used to provide a characteristic profile of Hispanic college student marijuana use. Eight percent reported past 30-day marijuana …

A Comparison Of The Basics Harm Reduction Approach And Personalized Normative Feedback For Reducing Alcohol-Related Behaviors Among Municipal Firefighters, Stormy Miracle Monks

Open Access Theses & Dissertations

Firefighting is a hazardous occupation due to the nature of firefighting duties including frequent exposure to traumatic events. Firefighters have been shown to cope with stress by drinking alcohol (Bacharach, Bamberger, & Doveh, 2008). Indeed, studies of firefighters have found that roughly 30% report being problem drinkers (Boxer & Wild, 1993) and 47% of firefighters have a diagnosis of alcohol abuse or dependence (North, Tivis, McMillen, Pfefferbaum, Spitznagel et al., 2002). Despite high rates of alcohol use, most firefighters receive inadequate training regarding alcohol and other risky behaviors. Furthermore, fire departments rarely act proactively regarding problems like alcohol consumption.

The …

Organic Photovoltaics: A Charge Transfer Perspective In The Study Of Donor-Acceptor Pairs, Marco Olguin

Open Access Theses & Dissertations

The present research involves the study of donor-acceptor (D/A) dyad complexes from a charge transfer energy perspective. The aim is to provide insight and predictive understanding into the charge transfer processes of the molecular-level components in donor-acceptor based organic solar cells using computational methods to describe photochemical processes at the quantum mechanical level within the Density Functional Theory (DFT) approximation. Predictive understanding is anchored in reproducing experimental results, wherein the present work a perturbative excited-state DFT method is described in detail and shown to give CT energies in excellent agreement with benchmark experimental data. With an accurate excited state method …

Employers' Perceptions Of Factors Related To The Workforce Development Of Community Health Workers In El Paso, Texas: A Descriptive Study, Aurora Aguirre Polanco

Open Access Theses & Dissertations

Workforce studies are necessary for regional economic development and for having a diverse workforce that meets the communities' needs. Workforce studies explore the most salient factors of models aimed at balancing economic forces of supply and demand. Community Health Workers (CHWs) are frontline health workers recognized by both the United States (US) Department of Labor (DOL) and the Patient Protection and Affordable Care Act of 2010 (PPACA). CHWs' service is oriented towards health promotion and disease prevention; they deliver public health interventions.

External and internal factors to the US health care system such as health care and wealth disparities, changing …

Correlates Of The Hepatitis C Virus Among Injection Drug Users And Their Sex Partners In Ciudad Juarez, Leilani Attilio

Open Access Theses & Dissertations

Background: The drug using risk behaviors associated with injection drug use are a major public health issue due to the increased risk of contracting blood- borne pathogens such as the Hepatitis C Virus (HCV). Needle and syringe sharing is well established to be an efficient mode of transmission of HCV. The prevalence of HCV among injection drug users (IDUs) in Cd. Juarez is documented to be over 90%. However, the literature on the sexual transmission of HCV is minimal. Methods: The aim of this cross-sectional pilot study was to determine the prevalence and correlates of HCV and risk …

Disparities In Park Availability, Features, And Characteristics By Social Determinants Of Health Within A U.S.-Mexico Border Urban Area, Amir Kamel

Open Access Theses & Dissertations

Background: Parks have been shown to be a key feature in the built environment that promote physical activity and positively influence health. However, a number of studies have highlighted that park availability, park features (e.g., park facilities, amenities, and aesthetic features), and park characteristics (e.g., quality/safety concerns of the park and surrounding neighborhood) are not equally distributed across neighborhoods in the U.S, specifically areas of low socioeconomic status and diverse racial/ethnic composition. The overall aim of this study was to examine and describe park availability, park features, and park characteristics, and determine their association with two social determinants of health …

Assessing Cortical Electrophysiologic And Behavioral Activity In Individuals With Aphasia And Participants With No Brain Damage Responding To Spoken Sentence Length Messages, Patricia Lara

Open Access Theses & Dissertations

In this study, six individuals with aphasia and twelve participants with no brain damage responded to spoken sentence length messages using a modified version of the Revised Token Test (McNeil & Prescott, 1978) while cortical activation was recorded using event related potentials (ERP). ERP is a non-invasive imaging procedure that measures cortical activation reflected in the electrical activity that is produced at the level of the cortex in response to internal or external stimulus.

Participants were presented with a visual display that provided eight different token arrangements per trial that were displayed on the computer screen. Spoken messages that increased …