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Full-Text Articles in Medicine and Health Sciences

Does Non-Steroidal Anti-Inflammatory Drug (Nsaid) Use Affect Dementia Progression And Survival Rates In Alzheimer's Disease? The Cache County Study, Trevor R. Buckley Dec 2011

Does Non-Steroidal Anti-Inflammatory Drug (Nsaid) Use Affect Dementia Progression And Survival Rates In Alzheimer's Disease? The Cache County Study, Trevor R. Buckley

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Alzheimer's disease (AD) has multiple factors that contribute to the disease process. Among these is a state of chronic inflammation that is endured by the brain during the aging process. The use of non-steroidal anti-inflammatory drugs (NSAIDs) decreases the amount of neuroinflammation sustained by the brain, and greater levels of NSAID use have been demonstrated to be associated with decreased probability of developing AD. This study looked at whether greater rates of NSAID use were also associated with decreased rates of cognitive and funtional decline and survival in a population-based sample of persons with AD. Linear mixed models failed to …


Neuropsychological And Neurophysiological Effects Of Low-Intensity Strengthening Exercise On Cognition, Vadim V. Yerokhin Jun 2011

Neuropsychological And Neurophysiological Effects Of Low-Intensity Strengthening Exercise On Cognition, Vadim V. Yerokhin

Honors Theses

With the growing aging population, it’s becoming increasingly important to find ways to either deter or prevent dementia. To date, most research has concentrated on the effects of aerobic exercise on cognition. Unfortunately, a large portion of older adults are often contraindicated to perform aerobic exercise due to different risk factors, which increase with age. Alas, alternate ways of exercise are necessary. Low-intensity strengthening exercise is a type of exercise aimed at improving balance and strengthening muscles without requiring one to overstrain. The current 11-week long exercise study test neuropsychological effects of exercise with a neuropsychological battery and neurophysiological effects …


Assessment Of Occupational Competence In Dementia: Identifying Key Components Of Cognitive Competence And Examining Validity Of The Cognitive Competency Test, Briana M. Zur Apr 2011

Assessment Of Occupational Competence In Dementia: Identifying Key Components Of Cognitive Competence And Examining Validity Of The Cognitive Competency Test, Briana M. Zur

Electronic Thesis and Dissertation Repository

Considering the links between dementia and everyday living, occupational therapists are called upon to make recommendations regarding appropriate living arrangements for persons with dementia. Re-framed as occupational competence, this is often accomplished by an evaluation of cognitive competence. Within the context of an aging population, a key question is how to best inform decisions regarding occupational competence, using cognitive competence as an indicator. The Cognitive Competency Test (CCT) is a tool used to evaluate cognitive competence and inform judgments about occupational competence in individuals with dementia. This thesis incorporates two studies that identified cognitive components that predict occupational competence in …


The Lived Experience Of Young-Onset Dementia, Debra A. Hunt Jan 2011

The Lived Experience Of Young-Onset Dementia, Debra A. Hunt

Electronic Theses and Dissertations

The lived experiences of dementia in older persons have been well studied, but the unique experiences of persons between ages 35 and 65 years who are living with young-onset dementia have not been closely examined. The purpose of the research was to explore the experiences of middle-aged individuals living with young-onset dementia. Van Manen‘s (1990) approach to interpretive phenomenological inquiry was used to answer the research question. Purposive sampling was used to recruit 9 people between 42 to 61 years of age who had received a formal diagnosis of mild or early-stage dementia. Participants were prescreened for the ability to …


Time Of Day Effects On Language Discourse In Healthy Aging And Dementia, Amanda L. Stead Jan 2011

Time Of Day Effects On Language Discourse In Healthy Aging And Dementia, Amanda L. Stead

LSU Doctoral Dissertations

This study’s purpose was to investigate whether language discourse follows a diurnal pattern across one 10-hour day in normal healthy aging individuals (NHA) and individuals with mild to moderate Alzheimer’s disease. Ten healthy older adults; and ten older adults clinically labeled with probable Alzheimer’s disease were recruited for this study. Measurements of procedural language, narrative language, and cognition, the Benton Judgment of Line Orientation (BJLO), were collected across one day at 9:00am, 12:00pm, 3:00 pm, and 6:00pm. Language samples were evaluated for linguistic variables to evaluate the quantity and quality of the discourse samples. Results indicated that the two groups …