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Full-Text Articles in Medicine and Health Sciences

The Impact Of Single Nucleotide Polymorphisms On Cortisol Receptor Activity In Populations With Obesity, Cassidy Michalicka Jun 2022

The Impact Of Single Nucleotide Polymorphisms On Cortisol Receptor Activity In Populations With Obesity, Cassidy Michalicka

Honors Theses

Cortisol is a crucial part of the endocrine system; it has the capacity to affect nearly every organ and tissue in the human body. When functioning correctly, cortisol is known to regulate the body’s stress response, control metabolism, suppress inflammation, regulate blood pressure, regulate blood sugar, regulate our body’s circadian rhythm, and much more. When the concentration of cortisol in the blood is elevated for an excessive period, the body responds with symptoms such as hyperglycemia, hypertension, weight gain, and moon face. Commonly this is known as Cushing’s Syndrome (CS), and interestingly, we have seen a phenotypic resemblance when contrasted …


Social Consequences Of Obesity: Case Study Of Bariatric Population At Ellis Hospital, Kara Leyden Jun 2020

Social Consequences Of Obesity: Case Study Of Bariatric Population At Ellis Hospital, Kara Leyden

Honors Theses

Despite the fact that the majority of adults living in the United States are overweight or obese, obesity remains a highly stigmatized physical condition. Society often sees obesity as a physical manifestation of personal faults such as the lack of self-control and laziness. Obese individuals thus experience discrimination in places of employment, have lower educational attainment, are underrepresented in popular culture, and often have difficulty finding and sustaining intimate relationships. For individuals with extreme obesity (BMI greater than 40), bariatric surgery is the most effective strategy to improve health and lose weight. Individuals who have undergone bariatric surgery typically experience …


The Business Cycle And Health: An Analysis Of How Macroeconomic Conditions Impact Health Outcomes In The U.S., Talitha Kumaresan Mar 2019

The Business Cycle And Health: An Analysis Of How Macroeconomic Conditions Impact Health Outcomes In The U.S., Talitha Kumaresan

Honors Theses

The U.S. spends about twice as much per person on healthcare, yet the disease burden remains higher in the U.S. than in comparable countries (Sawyer and Cox 2018; Sawyer and Gonzales 2017). Although health status is perceived to be an outcome of individual decision making, the business cycle also affects health. While the effect of macroeconomic shocks on health outcomes has been studied extensively, results remain inconclusive. This analysis uses longitudinal data over 30 years and panel data models to examine the effect of macroeconomic conditions on obesity, diabetes, hypertension, depression, congestive heart failure, and heart attack or myocardial infarction. …


Assessing Glucocorticoid Receptor Polymorphisms In Obese Populations, Ayanah Dowdye Jun 2018

Assessing Glucocorticoid Receptor Polymorphisms In Obese Populations, Ayanah Dowdye

Honors Theses

The glucocorticoid receptor (GR) is part of a family of nuclear receptors that control gene expression. In the presence of the steroid hormone cortisol, certain genes are expressed; the products of which control certain features of the body, including but not limited to, blood pressure, serum triglycerides, and blood sugar. There is evidence that these features are major contributors to obesity. Specific polymorphisms of the GR and other regulators of either GR or the closely related mineralocorticoid receptor such as heat shock protein 90 and 11ß-hydroxysteroid dehydrogenase type 1 have been found in our labs and others to be present …


The Linkage Between Hpa Axis Dysregulation And Metabolic Syndrome, Brianna Godlewski Jun 2017

The Linkage Between Hpa Axis Dysregulation And Metabolic Syndrome, Brianna Godlewski

Honors Theses

A diagnosis of Metabolic Syndrome (MSX) requires patients to present with three or more of the following symptoms: elevated fasting blood glucose levels, elevated serum triglyceride levels, low serum HDL levels, elevated blood pressure, and truncal obesity. This pathology shares many similarities with Cushing’s Syndrome (CS) but a diagnosis of CS requires hypercortisolemia. This similarity has led our lab and others to hypothesize that MSX may be a Cushingoid-like state caused by hypersensitivity of the glucocorticoid receptor (GR), a nuclear hormone receptor that is activated when cortisol binds, and or hyperactivity of the enzyme 11beta-hydroxysteroid dehydrogenase (11?- HSD) type 1, …


The Connection Between Gasoline Prices And Physical Activity: Potential Ways To Combat The Rise In Obesity, John Perrotti Jun 2017

The Connection Between Gasoline Prices And Physical Activity: Potential Ways To Combat The Rise In Obesity, John Perrotti

Honors Theses

It is widely understood that one of the most significant public health challenges in the United States is obesity which could rightly be considered an epidemic. Accompanied by billions of dollars in both explicit and implicit costs obesity places great strain on the health care system and economy as a whole. Years of scientific research has linked obesity to three main determinants: genetics over-eating and lack of physical activity. Recent research has introduced the study of the connection between the macro-economy and rates of physical activity thus linking economic variables to obesity. This paper investigates the connection between gasoline prices …


Product Bundling In Fast Food Advertisements And The Relationship With Consumers' Willingness To Pay, Madison Shapiro Jun 2017

Product Bundling In Fast Food Advertisements And The Relationship With Consumers' Willingness To Pay, Madison Shapiro

Honors Theses

Obesity rates have been rapidly increasing in recent years. This is a problem especially for low-income families and for households without access to quality food. Consequently fast food restaurants are a solution for those who cannot afford healthy food. The large number and variety of fast food restaurants coupled with their aggressive advertisements cheap prices and large portions may have an effect on consumption and obesity rates. This study explored the relationship between types of advertisements utilized by fast food restaurants and consumers' willingness to pay (WTP) to see if bundled advertisements have a significant impact on WTP. Bundles also …


Rising Obesity: An Unintended Consequence Of The Anitsmoking Campaign?, Hunaiz Patel Jun 2012

Rising Obesity: An Unintended Consequence Of The Anitsmoking Campaign?, Hunaiz Patel

Honors Theses

Obesity is the fastest growing health issue currently in the United States, as its prevalence has risen to over 30%, up from 14% in 1980 (Chou et al. 2004). As a result, the percentage of the population dealing with chronic health conditions has also been on the rise. Although the obesity epidemic is on the rise, smoking rates in the United States have declined from 33% to under 20% over the same time period, and from about 42% in 1965 (Todeschini et al. 2010). Thus, many economists have inferred that the declining smoking prevalence may partially be contributing to the …


From The Gas Pump To Our Hips: The Impact That U.S. Corn-Ethanol Production Has On America's Obesity Epidemic, Scott Reddy Jun 2012

From The Gas Pump To Our Hips: The Impact That U.S. Corn-Ethanol Production Has On America's Obesity Epidemic, Scott Reddy

Honors Theses

The purpose of this study is to examine the effect that increased U.S. corn-ethanol production has on food prices and, in turn, the diet choices of the U.S. population. Previous literature has confirmed the linkages between the energy market and the corn market and has separately examined the relationship between relative food prices and obesity. The purpose of this study is to link ethanol production to obesity. The first two sections of the model will utilize various econometric techniques to test the existence of certain empirical relationships over the period of January 1982-May 2011. The final stage will employ ordinary …


Obesity In The United States: The Food Environment And How It Is Linked To Obesity, Meredith Allenick Jun 2012

Obesity In The United States: The Food Environment And How It Is Linked To Obesity, Meredith Allenick

Honors Theses

The rising obesity rates have been constantly discussed in the media, academia, science, and society in the United States; from root causes and possible solutions to effects on individual health and the health of our nation. In my thesis, I focus on the social and economic causes of obesity, especially on the food environment in the United States. My ultimate goal is to effectively argue that obesity a problem rooted in society, often caused by factors such as the price of food, the availability of food, and the mass marketing of food to both children and adults.