Medicine and Health Sciences Commons^™

Designing A Sustainable And Transferable Inventory Management System For Small Healthcare Facilities, Shree Frazier

Open Access Theses

Managing the costs of supplies within healthcare facilities has been a task that has plagued the health industry for many years. Many facilities are accustomed to using a par system approach. This involves bringing an inventory item to an amount sufficient for daily operation. This method often requires daily inspection by a healthcare worker, which reduces his/her time spent performing value added tasks. Employees at small healthcare facilities have multiple responsibilities, therefore they cannot afford to spend much time on inventory management. A proposed approach is the Kanban method, which allows for strict monitoring of inventory items without the need …

The Impact Of An Omega-3 Enriched Diet On Hyperactivity And Biochemistry In An Animal Model For Attention-Deficit/Hyperactivity Disorder, Nadine M. Hammoud

Open Access Theses

Attention-deficit/hyperactivity disorder (ADHD) is the most diagnosed behavioral disorder in children. It affects around 5% of children worldwide and 11% of children in the United States, with rates increasing. Pharmaceutical treatments, such as amphetamines and methylphenidates, are not effective for everyone and are known to have unwanted side effects. While the etiology of the disorder is not yet fully understood, there are clear genetic and environmental components. Nutritional insufficiencies have recently become a popular environmental risk factor under investigation. Essential fatty acids (EFA), omega-3 polyunsaturated fatty acids (PUFA) in particular, are needed for proper brain development and function. Our lab …

Respiratory And Laryngeal Function In Teachers Pre- And Posta 1-Hour Vocal Loading Challenge, Nicole E. Herndon

Open Access Theses

Teachers use their voice as a key part of their profession, often speaking at an increased loudness for multiple hours a day. This places teachers at a high risk for voice disorders, which costs the United States billions of dollars annually. Vocal fatigue, or worsening of the voice as the day progresses, is a common complaint from teachers. The present study investigated respiratory and laryngeal function in teachers pre and post a 1-hour vocal loading challenge. Six teachers and three student teachers (total of 9 subjects) produced four speech tasks and completed two perceptual ratings pre and post a 1-hour …

Pharmacist Collaborative Drug Therapy Management In U.S. Hospitals, Pragya Mishra

Open Access Theses

The objectives for this study were to 1) assess the current extent, scope and perceptions of CDTM in U.S. hospitals, 2) determine the associations between hospital characteristics, pharmacy director characteristics, and perceptions of CDTM, 3) investigate hospitals' short-term and long-term plans regarding CDTM, and 4) identify pharmacy directors' views about the major facilitators and barriers for CDTM in hospitals.

A self-administered written survey was mailed to a national random sample of hospitals stratified by state. Pharmacy directors indicated whether any pharmacists were engaged in CDTM, what CDTM activities were permitted, and in what treatment categories CDTM was permitted. Demographic data …

Prediction Of The Stress At The Inlet Of The Nip Region In A Roll Compactor, Timothy Patterson

Open Access Theses

The stress at the inlet nip region of a roll compactor (i.e., feeder outlet stress) is a necessary input parameter for existing powder roll compaction models; however the nip region inlet stress is poorly understood and difficult to directly measure. The inability to specify the nip region inlet stress on a roll compactor limits comparisons between powder roll compaction models and experimental results. Therefore, this thesis investigates the application of a solid plug model to a powder feed screw of a roll compactor in order to predict the stress at the inlet nip region.

The feeder outlet stress predictions of …

Risk Attitudes And Characteristics Of Student Pharmacists Across Cohorts, Kristin Rose Villa

Open Access Theses

In unstable environments, adaptation is a prerequisite for survival of organizations or groups. The Affordable Care Act has created a changing environment for health care providers. Unfortunately for Pharmacy, innovation within our profession has languished, leaving pharmacists in a precarious position. Many have noted the stagnation of the profession; in fact it has been a recurring theme in the commentary over the last five decades. The dialogue has focused on the externalities that represent barriers to the profession's evolution, including the direction change should take and the legal or organizational issues that inhibit change and innovation. Little attention has been …

Nanotechnology And Additive Manufacturing Platforms For Clinical Medicine: An Investigation Of 3d Printing Bioactive Constructs And Halloysite Nanotubes For Drug Delivery And Biomaterials, Jeffery A. Weisman

Doctoral Dissertations

Personalized medicine requires the development of new technologies for controlled or targeted drug delivery. Three-dimensional (3D) printing and additive manufacturing techniques can be used to generate customized constructs for bioactive compound delivery. Nanotechnology in the form of nanoparticles, used as a stand-alone construct or for material enhancements, can significantly improve established biomaterials such as PMMA based bone cements or enable new technology to have enhanced capabilities. Combinations of the technologies can be used in such applications as infectious disease treatments, chemotherapeutic targeted drug delivery or targeted delivery of nearly any bioactive compound.

Chemotherapeutic or antibiotic enhanced 3D printing filaments were …

Epidemiology Of Coccidioidomycosis In Missouri, Ravi Kumar Aggu Sher

Open Access Theses

Introduction. Incidence of Coccidioidomycosis has been increasing nationally, from 2,271 cases in 1998 to 17,802 cases in 2012. Missouri is not endemic to Coccidioidomycosis but the incidence has been increasing since becoming reportable in 2003. To describe epidemiology of Coccidioidomycosis in Missouri we conducted a retrospective review of surveillance data at Missouri Department of Health & Senior Services (DHSS) for the years, 2004-2013.

Methods. Data was obtained from Missouri Health Surveillance Information System (WebSurv), the statewide reporting system for notifiable diseases. All cases that were "Confirmed" were included in the study.

Results. There were a total of 93 confirmed cases …

1,25-Dihydroxyvitamin D Alters Lipid Metabolism And Epithelialto- Mesenchymal Transition In Metastatic Epithelial Breast Cancer Cells, Alle Nicole Barnard

Open Access Theses

Evidence suggests that high vitamin D status (marked by serum 25-hydroxyvitamin D, 25(OH)2 D) is associated with a decreased risk of breast cancer. It has been established that 1,25-dihydroxyvitamin D (1,25(OH) 2 D) can alter glycolysis and the Krebs cycle of breast cancer cells (Jiang et al., 2010; Zheng et al., 2013) but little information is available on 1,25(OH) 2 D's alterations of lipid metabolism in breast cancer cells. Thus, the current research investigates if there was an effect of 1,25(OH) 2 D on proteins that regulate lipid metabolism in MCF10A, MCF10A-ras, MCF10CA1h, and MCF10CA1a epithelial breast cancer cells. While …

Pharmacokinetics And Toxicity Of The Novel Oral Demethylating Agent Zebularine In Laboratory And Tumor Bearing Dogs, Christopher Michael Fulkerson

Open Access Theses

The aim of this thesis is to investigate the pharmacokinetics and toxicity of the novel oral demethylating agent zebularine (zeb) in laboratory dogs and tumor bearing dogs. This thesis focuses on the application of this therapeutic strategy in dogs with naturally occurring invasive transitional cell carcinoma (InvTCC), which serve as a relevant model of the human disease.

DNA hypermethylation in the promoter region is a common epigenetic change in cancer that silences tumor suppressor genes. Zeb is an oral cytidine analog that acts as a demethylating agent. Zeb has been investigated extensively in vitro as well as in mice, rodents …

Factors Affecting Attitudes Towards Individuals With Schizophrenia: Perceptions Of Mexican American College Students, Valerie Paredes

Theses and Dissertations - UTB/UTPA

This study is designed to examine the effects of acculturation and level of familiarity on stigma of Mexican American college students towards individuals with schizophrenia along the border of Texas and Mexico (N = 223). The area has a history of high levels of disparity in regards to the utilization of mental health services. Data was collected by surveying Mexican American college students through a convenience sample at two separate post-secondary southwestern Hispanic-Serving Institutions (HSIs) along a border community. The instrumentation for the study was composed of a demographic questionnaire, The Acculturation Scale for Mexican-Americans-II (Cuéllar, Arnold, & Maldonado, 1995), …

Impact Of Healthy Lifestyle Choices On Smoking Behavior Among College Students Who Smoke Cigarettes, Mitchell Jenkins

Graduate Theses and Dissertations

This dissertation examines the impact certain healthy lifestyle choices had on smoking behavior among college students who smoke cigarettes. Even with continued reduction in prevalence, cigarette smoking is still the leading cause of preventable death in America. With that in mind, it is important to continue to identify factors that relate to decreased tobacco usage. Secondary data from the American College Health Association's bi-yearly National College Health Assessment was used for this study. This assessment/survey encompasses college students' habits, behaviors, and perceptions regarding prevalent health topics. The sample for this study consisted of 14,515 college students who identified themselves as …

A Comparison Of The Effects Of Soundfield Amplification On Acoustical Characteristics And Word Recognition Performance In Relocatable And Permanent Classrooms, Sarah M. Babin

Doctoral Dissertations

There are three acoustical characteristics that should be addressed when developing a good classroom listening environment: signal-to-noise ratio (SNR), reverberation time (RT), and levels of background noise. Previous research has shown that soundfield (SF) amplification systems help to improve these three characteristics, thus improving the classroom listening environment. In the present study, two seventh-grade classrooms were used: one relocatable classroom and one permanent classroom. Acoustical characteristics and speech levels were measured in both classrooms under two amplification conditions (unamplified and amplified). Word recognition abilities of 37 students were also measured under the two amplification conditions in both classrooms. Results showed …

Evidence-Based Health Literacy Training Program For Occupational Therapy Professionals : Program Development And Evaluation, Cheryl Miller-Scott

Occupational Therapy Program Student Theses, Dissertations and Capstones

This capstone project is a training program development and evaluation project. The purpose of the project was to develop, pilot, and evaluate an

evidence-based health literacy training program for occupational therapy professionals. Occupational therapy strives to be a science-driven profession, which provides client-centered care. Health literacy is a client-centered factor for which occupational therapy professionals require additional training to best serve their clients in all settings and across the lifespan. A review of health literacy literature was used in this project to develop the training program and offers a science-driven approach to this client-centered factor for occupational therapists to better …

Feasibility Of Pulsed Proton Induced Acoustics For 3d Dosimetry, Fahed M. Alsanea

Open Access Theses

Proton therapy has the potential to deposit its energy in tissue with high conformity to the tumor and significantly reduced integral dose to normal tissue compared to conventional radiation, such as x-rays. As a result, local control can be enhanced while reducing side-effects and secondary cancers. This is due to the way charged Particles deposit their energy or dose, where protons form a Bragg peak and establish a well-defined distal edge as a function of depth (range). To date, the dose delivered to a patient from proton therapy remains uncertain, in particular the positioning of the distal edge of the …

Controlling Protein Release Using Biodegradable Microparticles, Benjamin Patrick Kline

Open Access Theses

Research in the field of protein therapeutics has exploded over the past decade and continues to grow in both academia and in industry. Protein drugs have advantages of being highly specific and highly active making them coveted targets for high profile disease states like cancer and multiple sclerosis. Unfortunately, their many advantages are complemented by their obstacles. Because proteins are highly active and highly specific, the window between efficacy and toxicity is very narrow and drug development can be long and arduous. In addition, protein activity is dependent on its specific folding conformation that is easily disrupted by a variety …

Modeling And Optimization Of Care Transitions, Yuming Mo

Open Access Theses

More than 145 million people live with at least one chronic condition, and almost half of them have multiple conditions. As a result, many managed care and integrated delivery systems have taken a great interest in alleviating the many deficiencies in managing the current care system that spans across various care delivery settings. In addition, many Americans have to rely on some social health insurance plan to cover her care expenses. As a result, these patients often may not been sufficiently cured but have to be transitioned to less expensive but less medically intensive facilities, due to the increasing pressure …

Physical Activity Informational Websites: Accuracy, Language Ease, And Fear Appeal, Samantha Rose Paige

Open Access Theses

Introduction. Health information is one of the most common searches on the Internet. Literature supports that, in general, health information readily available to Internet consumers is not accurate, lacks plain language for ease of understanding, and does not incorporate behavior-change theoretical frameworks. The purpose of this study was to evaluate each of these components. Method. Three keywords, "physical activity," "exercise," and "fitness," were entered into four popular search engines: Google, Bing, and Yahoo. The first 5 result pages were considered, totaling a sample of 493 websites. After exclusionary criteria, 102 websites were reviewed and analyzed with guidance from ACSM recommendations, …

The Relationship Between Perceived Discrimination And Hope For The Future, Global Self Worth And Academic Competence: In A Multi-Racial/Ethnic, Low Income Sample Of School Age Children, Grace Elisabeth Quattrocki

Open Access Theses

Objective: To examine the extent to which a change in perceived interpersonal discrimination was associated with a change in the levels of hope for the future, global self-worth and perceived academic competence among a multiracial sample of adolescents attending a four-week, summer positive youth development program. Method: We first estimated means with standard errors of continuous variables and percentages within categorical variables in our total sample, and between those returning to PALS and those who were new to PALS. We then examined the correlation between perceived interpersonal racial/ethnic discrimination and the three outcome variables at the beginning and end of …

An Exploratory Analysis Of Fruit And Vegetable Consumption In Black Men, Jacqueline Reiter

Open Access Theses

Objective: Multiple peer-reviewed studies have found an association between fruit and vegetable consumption and lower risk for diseases such as hypertension, stroke and cancer. In other related studies, education level, retail food environment, and fruit and vegetable consumption were also examined together to discover patterns and associations. Currently, Black males have a higher risk for poor health outcomes. Limited research has focused specifically on Black men's fruit and vegetable consumption. This study explored the association between education level, food store access (measured by proximity) and fruit and vegetable consumption in black African American men.

Design: The data for this study …

Pharmaceuticals And Personal Care Products: Emerging Contaminants In Aquatic Ecosystems, Jenny E. Zenobio

Open Access Theses

In recent years, the presence of pharmaceuticals and personal care products (PPCPs) in aquatic systems has led to research on their fate and effects. PPCPs have been found in mixture in wastewater effluents, surface, ground, and drinking water at low concentrations from areas of intense urbanization. Although adverse effects to human health from the current environmental concentrations are unlikely, the impacts to ecological receptors are not clear. We performed field and laboratory studies to quantify and evaluate effects of PPCPs on fish. First, a field study was conducted at the Baca National Wildlife Refuge, Colorado (2010-2012) because a portion of …

The Effect Of Hearing Aid Program On The Perceived Sound Quality Of Music, Kalyn Kennedy Bradford

Doctoral Dissertations

Hearing loss affects many aspects of people's lives, including both communication and their ability to enjoy music. Currently, however, there is very little research on patient perception of music through hearing aids; therefore, the purpose of this study was to determine if there was a difference in the perceived listener satisfaction for music between a standard music program and the commonly used option for programming hearing aids (i.e., an automatic program). Data was collected using fifteen participants with symmetrical mild to moderately-severe sensorineural hearing loss with normal to near normal low frequency hearing. Participants were asked to listen to a …

Effect Of Noise On Transient-Evoked Otoacoustic Emissions And Pure-Tone Screening Audiometry, Laura Annette Wade

Doctoral Dissertations

Currently, the American Speech-Language Hearing Association (ASHA) recommends pure-tone audiometry as the preferred audiometric screening method of school-aged children; however, background noise is often present and can result in high referral rate. The current study's goal was to examine the effect of noise on the pass rate on transient-evoked otoacoustic emissions (TEOAEs) and pure-tone audiometric screening measures. Twenty normal hearing adults (M = 22.85), eighteen females and two males, were screened with TEOAEs and pure-tone audiometry in quiet and in different levels of noise (i.e., 40 dB SPL, 50 dB SPL, 60 dB SPL) in a sound-treated booth.

Pure-tone audiometry …

Exploring The Relationship Between Reporting Medication Errors And Nurse Fear Of Retribution, Emily J. Hanna

Nursing Theses and Capstone Projects

Studies have shown that medication administration errors are a critical issue in healthcare and more importantly preventing this type of error depends on precise reporting. Analysis of medication errors can lead to healthcare system improvement and reduced risk if the errors are detected, reported, and used to formulate improved patient care practices and systems. Nurses are the front line of defense to intercept and report errors. Through a review of the literature, it has been determined that nurses possibly fear blame and punishment when a Medication Administration Error (MAE) occurs; therefore, the purpose of this Master of Science in Nursing …

Utilization Review Software: The Impact On Productivity And Structural Empowerment In Case Management Nurses In An Acute Care Setting, Kimberly Frazier

Nursing Theses and Capstone Projects

The Center for Medicare and Medicaid (CMS) seeks to achieve cost control by implementing aggressive cost containment mechanisms for an exploding Medicare population. One such mechanism is utilization review, which is employed to limit reimbursement of medical care that is determined to not be medically necessary. The CMS Conditions of Participation mandate that all hospitals determine whether a patient qualifies for an Inpatient or Observation stay. Utilization Review Specialist (UR) nurses were given the Conditions of Work Effectiveness Questionnaire II (CWEQ-II), Organizational Relationship Scale II (ORS-II), and the Job Activity Scale II (JAS II), six months after McKesson InterQual software …

Nursing Students' Perceptions Of Mental Health Patients And Mental Health Nursing, Susan Furr

Nursing Theses and Capstone Projects

This Capstone project evaluated the impact of a simulation-based learning experience on nursing students' anxiety levels, preparedness for psychiatric practicum, and stereotypical views towards individuals with mental illness. A sample of 15 bachelor level nursing students was utilized. The experimental group (n=8) was exposed to a four-hour simulation-based learning experience prior to the beginning of their clinical experience. The control group (n=7) began their clinical rotation without any simulation exposure. A pretest, posttest design utilizing the Mental Health Nursing Survey Part 1 (MHN-1) and the Mental Health Nursing Survey Part 2 (MHN-2) was used to measure the students' stereotypical views, …

Measuring The Playfulness Of Children With Special Needs In Occupational Therapist Led, Caregiver-Included Community Playgroups, Sarah Fabrizi

Occupational Therapy Program Student Theses, Dissertations and Capstones

The aim of this study was to investigate the effectiveness of community playgroups on the playfulness of children ages 15 months to 3 years with special needs. In addition to playfulness of the child, the sensitivity and responsiveness of the caregiver were examined. A quasi-experimental, pretest-and-posttest, repeated measures design was used to follow eight children and their caregivers receiving early intervention services and taking part in a community playgroup. The children and their caregivers were measured during a 4-week standard-of-care baseline, before and after an 8-week intervention period, and 4 week post-intervention. The Test of Playfulness (ToP) was utilized to …

Planning For The Future : A Grounded Theory Study Of Well Older Adults' Decision-Making Regarding Home Modifications, Kathleen Subasic

Occupational Therapy Program Student Theses, Dissertations and Capstones

The purpose of this dissertation research was to understand the decision-making process that well older adults use when deciding whether to make a home modification. The researcher also sought to understand the views of well older adults concerning the use of home modification to prevent injury and declines in occupational performance. The researcher used the Person-Environment-Occupation (PEO) model (Law et al., 1996) from occupational therapy and occupational science as the orienting framework.

A qualitative grounded theory approach based on that proposed by Strauss and Corbin (1998) was used to structure data collection and analysis. Participants were obtained using purposive and …

Sensory Intervention To Improve Sleep Behaviors And Social Participation Of Children In Israel With Sensory Modulation Disorder, Geela Spira

Occupational Therapy Program Student Theses, Dissertations and Capstones

The aim of this study was to investigate a sensory intervention of moderate pressure touch on children with sensory modulation disorder on the outcomes of sleep behaviors and social participation. 50 children, aged 6-11 years, with both sensory modulation disorder and sleep difficulties were randomly divided into an experimental group and a control group. The experimental group participants received three weeks of nightly massage by their parents. The parents filled out questionnaires reporting on sleep behaviors, sensory modulation, and social participation, as well as recording a sleep log, and determining goal attainment scaling goals. The questionnaires used were the Short …

Core Professional Nursing Values As Experienced By Baccalaureate Nursing Students Who Are Men, Bonnie Schmidt

Student Theses, Dissertations and Capstones

Experts have called for greater diversity in the nursing workforce; however, men remain underrepresented in the nursing profession. The presence of cultural dissonance among male nursing students has been documented in prior research but little is known about their values that are culturally influenced. The purpose of this study was to understand and interpret the meaning of core professional nursing values to male baccalaureate nursing students. The research question was: what is the meaning of core professional nursing values to nursing students who are men.

The study setting was an undergraduate baccalaureate school of nursing in the Midwest. Using a …