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Full-Text Articles in Medicine and Health Sciences

Beliefs Concerning Role Of The Nursing Service Administrator In Hospitals As Expressed By Chief Executive Officers, Nursing Service Administrators, And Nurse Educators, Jimmie R. Williams Dec 1987

Beliefs Concerning Role Of The Nursing Service Administrator In Hospitals As Expressed By Chief Executive Officers, Nursing Service Administrators, And Nurse Educators, Jimmie R. Williams

Electronic Theses and Dissertations

This study was undertaken to determine the degree of relationship in perceptions held by three health care administrative groups between the desirable and actual role functions of the hospital nursing service administrator. This descriptive study surveyed hospital Chief Executive Officers (CEOs), and Nursing Service Administrators (NSAs) in 100 randomly selected general hospitals, and chairpersons of graduate programs in nursing service administration. The instrument for this study was the Beliefs Concerning Role of Hospital Nursing Service Administrator, a 12-item instrument designed to determine some of the desirable (optimal) and actual (currently performed) role functions of the hospital Nursing Service Administrator (NSA), …


Design And Evaluation Of Theophylline Monitoring For Home Health Care Patients, May Naim Mikhail Jan 1987

Design And Evaluation Of Theophylline Monitoring For Home Health Care Patients, May Naim Mikhail

University of the Pacific Theses and Dissertations

The purpose of this study was to design, evaluate, and determine the cost benefit of a pharmacokinetic service for home-based patients. Four randomly selected patient populations were used in evaluating the service for six months. The experimental group consisted of 17 patients who were under the care of family practice physicians in private practice and who received pharmacokinetic consultation and monitoring by a pharmacist as a home health care service. The retrospective control consisted of the same 17 patients of the experimental group whose past medical history for a period of six months was used. The concurrent control consisted of …


Investigation Of Physicochemical And Formulation Parameters For Transdermal Delivery Of Isoproterenol Hc1, Rajesh Arvindkumar Patel Jan 1987

Investigation Of Physicochemical And Formulation Parameters For Transdermal Delivery Of Isoproterenol Hc1, Rajesh Arvindkumar Patel

University of the Pacific Theses and Dissertations

Effects of solubility, partition coefficient, pH and selected adjuvants (propylene glycol and Azone) on the percutaneous penetration of isoproterenol HC1 in vitro have been investigated using human cadaver skin. Preliminary stability studies demonstrated that isoproterenol HC1 was very stable (less than 1% decomposition) for 24 hours at 22(DEGREES) (+OR-) 0.5(DEGREES) in the pH range 1 to 7 in the following solvents: water, normal saline, propylene glycol and a series of propylene glycol-water mixtures (10,20,40 and 60% v/v). The rate of decomposition of the drug in aqueous solutions increased with pH beyond pH 8. In normal saline, the decomposition was significant …


Opioid Receptor Effects Of Two Aminotetralin Derivatives In Guinea Pig Ileum Longitudinal Muscle And Mouse Vas Deferens Preparations, Francisca Fatima Matos Jan 1987

Opioid Receptor Effects Of Two Aminotetralin Derivatives In Guinea Pig Ileum Longitudinal Muscle And Mouse Vas Deferens Preparations, Francisca Fatima Matos

University of the Pacific Theses and Dissertations

Two substituted analogs of 3-amino-2,2-dimethyltetralin, namely 3-dimethylamino-7-hydroxy-2,2-dimethyl-1-tetralone HBr (J) and 3-dimethylamino-7-hydroxy-2,2-dimethyl-1-tetralol (MRSAL) were evaluated for opioid agonist and antagonist activity using the electrically-stimulated guinea pig ileum longitudinal muscle and mouse vas deferens preparations. The effects of these compounds in these tissues were compared to those induced by several opioid prototype agonists at mu, kappa and delta sites (normorphine, dihydromorphine, ethylketocyclazocine, U-50,488H, beta -endorphin, dynorphin 1-13, leu-enkephalin and DADLE) and one opioid antagonist (naloxone). The results of these experiments demonstrated that compound J inhibited contractions in a concentration-dependent manner as an opioid agonist and its effects were antagonized by naloxone in …