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Full-Text Articles in Medicine and Health Sciences
Physical Activity And Maternal/Fetal Outcomes In A Pregnant Latina Population, Audra L Gollenberg
Physical Activity And Maternal/Fetal Outcomes In A Pregnant Latina Population, Audra L Gollenberg
Doctoral Dissertations 1896 - February 2014
Physical activity guidelines encouraging activity among healthy pregnant women have been issued by the Centers for Disease Control and Prevention, yet Latina women remain more sedentary than non-Latina white women. Latina women are also at higher risk for gestational diabetes mellitus and, among Latina women, Puerto Rican women have the highest rates of low birth weight and preterm-related infant death. This dissertation utilized data from the Latina GDM study, a prospective cohort study of 1,231 Latina women recruited early in pregnancy and followed through delivery. Participants were interviewed in early and mid pregnancy for assessment of sociodemographics, acculturation, medical, and …
Do Metabolic And Psychosocial Responses To Exercise Explain Ethnic/Racial Disparities In Insulin Resistance?, Rebecca E Hasson
Do Metabolic And Psychosocial Responses To Exercise Explain Ethnic/Racial Disparities In Insulin Resistance?, Rebecca E Hasson
Doctoral Dissertations 1896 - February 2014
Introduction . Non-Hispanic blacks (blacks) are more insulin resistant compared to non-Hispanic whites (whites), increasing their risk for Type 2 diabetes. The role played by ethnic/racial disparities in the response to physical activity in mediating those higher rates of insulin resistance in blacks is unknown. Because the beneficial effects of exercise are transient and require subsequent doses of exercise to maintain the effect; the metabolic and psychosocial responses to single exercise bouts have strong implications for both opposing insulin resistance and raising the probability that an individual will continue to exercise. Purpose . To compare the metabolic and psychosocial responses …
Approaches To Estimation Of Haplotype Frequencies And Haplotype-Trait Associations, Xiaohong Li
Approaches To Estimation Of Haplotype Frequencies And Haplotype-Trait Associations, Xiaohong Li
Doctoral Dissertations 1896 - February 2014
Characterizing the genetic contributors to complex disease traits will inevitably require consideration of haplotypic phase, the specific alignment of alleles on a single homologous chromosome. In population based studies, however, phase is generally unobservable as standard genotyping techniques provide investigators only with data on unphased genotypes. Several statistical methods have been described for estimating haplotype frequencies and their association with a trait in the context of phase ambiguity. These methods are limited, however, to diploid populations in which individuals have exactly two homologous chromosomes each and are thus not suitable for more general infectious disease settings. Specifically, in the context …