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Medicine and Health Sciences Commons

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Theses/Dissertations

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1997

Yale Medicine Thesis Digital Library

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Full-Text Articles in Medicine and Health Sciences

Modulation Of The Rat Potassium Channel Kv1.5, Daniel Benjamin Saal Nov 1997

Modulation Of The Rat Potassium Channel Kv1.5, Daniel Benjamin Saal

Yale Medicine Thesis Digital Library

1. Kv1.5 is a delayed rectifier-type potassium channel. We have examined the localization of the channel protein using a polyclonal antibody against Kv1.5. This channel is expressed in numerous regions of the brain, primarily in glial cells. Its expression is particularly intense in the endfoot processes which abut the microvasculature of the brain. It is also expressed in the cell bodies and cellular processes in the pituitary.2. Immunoprecipitation of the Kv1.5 protein, from HEK 293 cells which were transformed with the Kv1.5 gene, revealed that the channel is phosphorylated and that treatment of cells with dibutyryl cyclic AMP (dibcAMP) or …


Effect Of Phenobarbital On Extracellular Matrix Production, Cell Replication, Transforming Growth Factor-��1 Binding, And Tgf-�� Receptor Profile In Rat Dermal Fibroblast Cultures, Rani Karina Spudich Jan 1997

Effect Of Phenobarbital On Extracellular Matrix Production, Cell Replication, Transforming Growth Factor-��1 Binding, And Tgf-�� Receptor Profile In Rat Dermal Fibroblast Cultures, Rani Karina Spudich

Yale Medicine Thesis Digital Library

No abstract provided.


Statistical Parametric Mapping Analysis Of Positron Emission Tomography Images For The Detection Of Seizure Foci: Results In Temporal Lobe Epilepsy, Jeffrey R. Tseng Jan 1997

Statistical Parametric Mapping Analysis Of Positron Emission Tomography Images For The Detection Of Seizure Foci: Results In Temporal Lobe Epilepsy, Jeffrey R. Tseng

Yale Medicine Thesis Digital Library

No abstract provided.