Medicine and Health Sciences Commons^™

An Animal Model For Development Of Pulpal Inflammation, John W. Masters

Loma Linda University Electronic Theses, Dissertations & Projects

Several animal models have been proposed to develop pulpal inflammation. Procedures recommended in these models have many variables and have not produced consistent results. The purpose of this study was to create pulpal inflammation using the Nd:YAG laser.

Forty-five cuspids of 12-18 month old beagle dogs were lased at 5, 7.5, and 10 watts (W) for 20 seconds with a 600 micron contact probe. Five cuspids were not lased but were used as controls. Following laser application, the teeth were extracted at intervals of 3, 7, and 30 days. They were then fixed in 10% formalin, decalcified, sectioned, and stained …

Change In Bracket Bond Strength And Enamel Calcium : Due To Repeated Bonding With Conventional And Resinomer Glass Ionomer Cements, David L. Wilkinson

Loma Linda University Electronic Theses, Dissertations & Projects

Glass ionomers chemically and mechanically bond to enamel. Repeated bonding may deplete calcium in enamel and reduce the bond strength. Seventy-five non-carious molars were randomly divided into three equal groups and metal brackets were bonded with either Ketac-Cem, Photac-Bond, or Fuji Ortho LC. The samples were stored in 100% humidity at 37° C for 7 days then shear/peel tested with an Instron machine. New brackets were repeatedly cemented with the same cement to the same tooth and shear/peel tested a total of five times. After each shear/peel test the tooth with the mean bond strength from each cement was set …

A New Soft Tissue Analysis : To Establish Facial Esthetic Norms In Young Adult Females, Anne Béress

Loma Linda University Electronic Theses, Dissertations & Projects

Two hundred and fifty-five articles, books, and masters theses were reviewed for the most frequently applied soft tissue measurements in the literature in order to develop a new soft tissue analysis computer program that includes established soft tissue measurements and the newly developed globe analysis. A meta analysis of 20 normal occlusion studies, was performed to obtain mean values and standard deviations to form a large sample size. Inclusion criteria for articles in the meta analysis were normal occlusion, no orthodontic treatment, pleasing faces, statement on age, race, and lip position of the population. For the lateral view, angular and …

In Vitro Plaque Formation On Orthodontic Resin Sealants, Leland W. Pack

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to examine in vitro plaque formation on sealant coated enamel. The plaque growth on different types of sealants placed on enamel was compared to each other and to an unsealed enamel control. The antimicrobial properties of sealants were also studied.

Sealant coated bovine enamel disks were immersed in a S. mutans culture medium for four days. The amount of bacterial plaque formation was quantified by removing the deposit, suspending it in solution with subsequent serial dilution. Aliquots of the dilutions were then spread on blood agar plates and incubated for 48 hours. The number …

Bone Morphogenetic Proteins And Periodontal Repair, Michael B. Lee

Loma Linda University Electronic Theses, Dissertations & Projects

For over thirty years now, research has been carried out to isolate and purify bone morphogenetic protein (BMP), a substance which has been shown to induce heterotopic bone formation in various animal species. Recent advances in the fields of developmental biology, molecular biology and genetics, have shown that the BMPs not only are responsible for postfetal bone induction (including normal bone remodeling, healing and repair), but are also critical during embryogenesis - not only in regards to the skeletal system, but quite possibly in the morphogenesis and pattern formation of other tissues and organs as well.

Due to their bone …

Treatment Effects Of The Edgewise Bioprogressive Herbst Appliance, Bernard C. Chang

Loma Linda University Electronic Theses, Dissertations & Projects

The effect of the Edgewise Bioprogressive Herbst appliance, as described by Dr. Terry Dischinger, was investigated on 24 Class II, Division 1 malocclusions. Mean pretreatment age of this sample was 11.2 months. All patients were treated by Dischinger with a Bioprogressive Herbst appliance. Lateral cephalographs taken before, after Herbst appliance therapy, and after edgewise treatment were traced, then digitized into Quick Ceph™. Measurements were computed by the computer software. The following results were found: 1) Average treatment time was 9 months. 2) An overcorrected Class I relationship was achieved. 3) Class II malocclusion was corrected by 4.5 mm skeletal alteration …

Pediatric Intensive Care Nurses : Post-Traumatic Stress Disorder-Like Symptoms, Juanita J. Allen

Loma Linda University Electronic Theses, Dissertations & Projects

Medical personnel are not only exposed to routine pressures of demanding roles, but research reveals that they can suffer from severe stress related to exposure to critical incidents. These events can overwhelm an individual's ability for emotional adjustment leading to negative symptoms such as emotional numbing, mood changes, estrangement from friends or family, decreased ability to perform or function on the job, development of posttraumatic stress disorder (PTSD) symptoms, loss of work through attrition, and depression. Contact with seriously injured children or children who have died has been shown to constitute just such a critical incident for pre-hospital care personnel …

The Effects Of Lowering Cholesterol On Vasodilation, Maria Christi Hardt

Loma Linda University Electronic Theses, Dissertations & Projects

Endothelial dysfunction has been found prior to any signs of atherosclerotic plaque formation in patients with a variety of risk factors for atherosclerosis. Elevated serum cholesterol has repeatedly been associated with endothelial dysfunction as demonstrated by impaired vasoreactivity to vasodilating stimuli.

The aim of this research was to determine whether short term lowering of serum cholesterol levels by life style changes or by cholesterol lowering medication could reverse or reduce the endothelial dysfunction. The brachial artery diameter was measured by high-resolution ultrasound at rest and during reactive hyperemia pre and postintervention. Fifty-three subjects with cholesterol levels above 240 mg/dl were …

Negotiating The Healthy Self: A Theory Of Health Behavior In Older Adults, Barbara Schwitz White

Loma Linda University Electronic Theses, Dissertations & Projects

Researchers have identified discrete behaviors of older persons to maintain or improve health and prevent or treat illness. Few have developed theories of health behavior specific to this population. The purpose of this study was to develop a substantive theory to explain how health and illness are integrated into and influence behaviors in the daily lives of community-residing older persons. Using grounded theory design and analysis, 26 participant observations involving 186 individual encounters, and seven semistructured [sic] one-on-one interviews were conducted at two senior centers in urban southern California, between 1992 and 1994.

Informants defined health in terms of physiologic …

Mutagenecity Of Formocresol, Glutaraldehyde, Ferric Sulfate And Aluminum Chloride : Materials Used In Therapeutic Pulpotomies, Adolfo Barrera

Loma Linda University Electronic Theses, Dissertations & Projects

Ferric sulfate (Astringedent) and aluminum chloride (Hemodent) have been proposed as possible medicaments for use in primary teeth for therapeutic pulpotomies.

There is little information in the literature about the biologic properties of these medicaments.

The purpose of this study was to evaluate the mutagenic response of the ferric sulfate and aluminum chloride and compare them with glutaraldehyde (1.5%, 1% and 0.5% concentration) and formocresol (2%, 0.75%, 0.01% and 0.005% concentration). TA98 and TA1535 strain were used in the Ames test to assess mutagenecity. Neither ferric sulfate nor aluminum chloride exhibited mutagenic potential, in comparison with glutaraldehyde and formocresol, which …

The Effect Of Guidor™ And Hop-1 On Hard Tissue Healing : Following Periradicular Surgery In Cats, Hugh Maguire

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to evaluate the effects of the resorbable membrane Guidor™ and the osteogenic protein hOP-1 on hard tissue healing following periradicular surgery in cats.

Surgical endodontic therapy was performed on the maxillary canine teeth of twelve cats. After orthograde root canal therapy, flap reflection, osteotomy, resection of the root end, root end cavity preparation and the placement of a root end filling, eight of the surgical sites were treated with Guidor™ and eight with hOP-1. The remaining eight sites received no further treatment and served as controls.

The animals were sacrificed at twelve weeks following …

Periodontal Repair In Dogs : Effect Of Recombinant Human Transforming Growth Factor Beta-1 On Guided Tissue Regeneration, Saghi Shayan Razi

Loma Linda University Electronic Theses, Dissertations & Projects

The objective of this study was to evaluate bone and cementum regeneration in the critical size, supraalveolar, periodontal defect model following surgical implantation of recombinant human transforming growth factor beta-1 (rhTGFß-1) in conjunction with guided tissue regeneration (GTR). Five male beagle dogs were used in a split-mouth design. Alternate jaw quadrants in consecutive animals received GTR with rhTGFß-1 in a resorbable calcium carbonate carrier. Contralateral jaw quadrants received GTR with carrier only (control). The healing interval was 4 weeks. Clinical healing was generally uneventful, however, minor membrane exposures were observed for both treatments with limited gingival inflammation. All defects with …

The Accuracy Of Computer Video Imaging Prediction : Just Prior To Surgical Mandibular Advancement/Genioplasty Orthognathic Cases, Jason T. Chiakowsky

Loma Linda University Electronic Theses, Dissertations & Projects

The accuracy of the computer video imaging treatment prediction was investigated using Quick Ceph Image.™ Thirty one surgical mandibular advancement/genioplasty orthognathic cases were examined to determine if the soft tissue profile prediction was representative of the actual result. All patients were over the age of 18. Lateral cephalographs and slides were taken immediately pre-surgically, and six months post-surgically. The slides were duplicated into 4X6 photographs. The cephalographs were digitized and the photographs captured by video on the Quick Ceph Image software program. A line drawing and computer video image treatment prediction were generated using the actual surgical change that had …

Association Between Nutrient Intake And Risk Of Coronary Heart Disease In California Seventh-Day Adventists, Peter Pribiš

Loma Linda University Electronic Theses, Dissertations & Projects

Dietary habits are believed to be major determinants of risk of coronary heart disease (CHD). Studies of high and low risk populations have suggested several nutrients to be protective or hazardous against CHD. Most published work since 1984 on diet and CHD in the Adventist Health Study (AHS) population examined either foods or food groups. This study investigated ten nutrients as exposure variables and their relationship to CHD risk. A cohort of 23,616 nonsmoking, non-Hispanic white California Seventh-day Adventists was followed for six years beginning in 1976. Extensive dietary information was collected at baseline, as well as values of traditional …