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Examining The Effects Of Oral Contraceptive Use On Thermoregulation, Whitley C. Atkins May 2022

Examining The Effects Of Oral Contraceptive Use On Thermoregulation, Whitley C. Atkins

Graduate Theses and Dissertations

Purpose: The purpose of this investigation was to evaluate the effects of combined (estradiol and progestin) monophasic oral contraceptive pill (OCP) use on thermoregulation. Further, we sought to evaluate OCP use on acute rehydration post-exercise in the heat using recommended rehydration guidelines. Methods: Twelve healthy, aerobically trained (VO2peak = 47.8 ± 4.7 mL/kg/min), long term female oral contraceptive users completed a familiarization trial and two experimental days separated by ≥ 7 days. The two experimental trials were identical except for the hormone dosing phase. One trial was completed during the third week of active pill dosing (ACT) and one during …


Implementing An Exercise Referral Scheme For Promoting Physical Activity In University Mental Health Care, Bryce Daniels May 2022

Implementing An Exercise Referral Scheme For Promoting Physical Activity In University Mental Health Care, Bryce Daniels

Graduate Theses and Dissertations

Introduction. Mental health symptoms and conditions are prevalent and increasing on college campuses with anxiety and depression having the highest increases in prevalence. Many college students are also physically inactive which is problematic as physical activity benefits mental health. Exercise referral schemes (ERS) can promote physical activity, though no studies have investigated the implementation of an ERS within a college counseling center. Purpose. The purpose of this dissertation was to investigate the implementation of an ERS for promoting physical activity in university mental health care. Methods. Study 1 used a qualitative descriptive design of 14 certified counselors to explore perceptions …


A Time-Course Characterization Of Muscle Function And Mitochondrial Markers During Colorectal Cancer-Induced Cachexia In Tumor-Bearing Male Mice, Ana Cabrera Ayuso Jul 2021

A Time-Course Characterization Of Muscle Function And Mitochondrial Markers During Colorectal Cancer-Induced Cachexia In Tumor-Bearing Male Mice, Ana Cabrera Ayuso

Graduate Theses and Dissertations

Cachexia is a multisystemic and multifactorial syndrome prevalent in cancer patients. It is clinically defined by involuntary loss of >5% weight in a six-month window, despite nutritional interventions. A negative energy balance characterizes cancer cachexia (CC), it is associated with weakness and fatigue in skeletal muscle. Impaired muscle function is associated with lower quality of life in cancer patients. Defects in mitochondrial function are strongly associated with muscle wasting. This study explored muscular contractile function and mitochondrial quality control (MQC) markers in soleus, gastrocnemius, and tibialis anterior (TA) muscles of C26-induced male tumor-bearing mice during a 25-day time course. It …


Mitochondrial Contributions To Disuse Atrophy: Let’S Talk About Sex, Megan Rosa-Caldwell Jul 2020

Mitochondrial Contributions To Disuse Atrophy: Let’S Talk About Sex, Megan Rosa-Caldwell

Graduate Theses and Dissertations

Skeletal muscle atrophy is a hallmark of many pathologies and is associated with disease prognosis, quality of life, and mortality. Specifically, lack of contractile activity of the muscle can result in disuse-associated atrophy. Disuse-induced atrophy is a common phenomenon in intensive care unit (ICU) patients and significantly impacts patient prognosis and ability to transition of out of intensive care. However, effective therapeutics to mitigate disuse-associated atrophy do not exist, clearly demonstrating the scientific and clinical need to further understand mechanisms contributing to disuse atrophy. In particular, a significant portion of the scientific literature has utilized male models, yet there is …


Influence Of Heating And Biological Sex On Vascular Dysfunction Associated With Long-Duration Sitting And Standing, Aaron Richard Caldwell Aug 2019

Influence Of Heating And Biological Sex On Vascular Dysfunction Associated With Long-Duration Sitting And Standing, Aaron Richard Caldwell

Graduate Theses and Dissertations

Purpose: The purpose of these studies was to determine if arterial angulations (through sitting or standing), shear stress (through local heating), or a combination of these factors affected vascular function. Moreover, this studied estimated the magnitude of the effect that biological sex has on these vascular responses. Methods: Twenty-six healthy, young (18-40 years old) males (n=13) and females (n=13) completed two experimental trials (2-h sitting and 2-h standing). In a randomized fashion, one leg was passively heated in order to increase shear rate. Following a 48-h washout, participants returned to the laboratory to complete the other trial. Flow-mediated dilation (FMD) …


Volumetric Muscle Loss: The Role Of Physical Activity And Autologous Repair On Force Recovery And Signaling Pathways, Richard Perry May 2019

Volumetric Muscle Loss: The Role Of Physical Activity And Autologous Repair On Force Recovery And Signaling Pathways, Richard Perry

Graduate Theses and Dissertations

Volumetric muscle loss affects both military and civilian persons. The hallmark of this injury is incomplete muscle regeneration, excessive fibrosis, and chronic inflammatory signaling resulting in permanent functional loss. Since permanent functional loss drastically reduces quality of life, many studies have been conducted to improve force recovery. Current scientific literature considers a repair strategy of either devitalized scaffolds infused with growth factors or viable tissue plus activating factors to be the more promising interventions for optimal force recovery. PURPOSE The purpose of this study is to incorporate autologous repair and physical activity and observe the effects of muscle force recovery …


Comparative Plasma Proteomics In Muscle Atrophy Induced By Cancer Cachexia And Hindlimb Unloading, Kirsten Rene Dunlap May 2019

Comparative Plasma Proteomics In Muscle Atrophy Induced By Cancer Cachexia And Hindlimb Unloading, Kirsten Rene Dunlap

Graduate Theses and Dissertations

Introduction: Muscle atrophy results from a dysfunction in protein turnover that leads to loss of mass and function and occurs concurrently with multiple pathologies such as cancer and extended bed rest. Atrophy reduces overall quality of life while increasing morbidity and mortality. Currently, efficacious therapeutic interventions to treat and prevent muscle wasting in all its forms are lacking, however if conserved mechanisms can be identified between wasting conditions, this would aid in the development of multipurpose therapeutics to ameliorate this pathology. Purpose: To examine circulating factors present across atrophic pathologies. Methods: 35 male C57BL/6J mice were assigned to hindlimb unloading …


Validation Of A 5-Minute Vpc Test To Assess And Compare Cognitively Intact Individuals And Individuals With Cognitive Impairments, Spencer Smith Jan 2019

Validation Of A 5-Minute Vpc Test To Assess And Compare Cognitively Intact Individuals And Individuals With Cognitive Impairments, Spencer Smith

Graduate Theses and Dissertations

The prevalence of cognitive impairments in the older adult population is growing. Finding treatment solutions to impede a cognitive decline can possibly lead to fewer cases of mild cognitive impairment, dementia, and Alzheimer’s disease. A Visual Paired Comparison (VPC) could serve as a tool to predict, monitor, and regulate people who are susceptible to a cognitive decline. The purpose of this study was to 1) to determine the validity of the Neurotrack 5-minute VPC test with the Neurotrack 30-minute VPC test, 2) to determine the test-retest reliability of the Neurotrack 5-minute VPC test, 3) to compare Neurotrack 5-minute VPC scores …


The Effect Of Dehydration On Metabolism And Energy Substrate Utilization, Zachary Robert Lewis Dec 2018

The Effect Of Dehydration On Metabolism And Energy Substrate Utilization, Zachary Robert Lewis

Graduate Theses and Dissertations

The purpose of this study was to measure hormonal and metabolic markers in humans to see if simulating dehydration would emulate measures that are seen in prediabetic humans. 60 volunteers were divided into equal categories by sex and body mass index of normal or overweight. Participants completed two oral glucose tolerance tests (OGTT) after being intravenously infused with a isotonic or hypertonic saline solution for 120 minutes in a counter balanced order. All trials began with a euhydrated subject with a urine specific gravity (USG)


The Relationship Between Mental Health And Ultra-Running: A Case Study, Joshua Justin Cook Aug 2018

The Relationship Between Mental Health And Ultra-Running: A Case Study, Joshua Justin Cook

Graduate Theses and Dissertations

This instrumental case study sought to explore the relationship between ultra-running and mental health through the lived experiences of a single participant who self-identifies as an ultra-runner. Three research questions were used to explore this relationship; how did the individual decide to participate in ultra-running, what aspects of ultra-running impact the participant’s mental health, and how has engaging in ultra-running impacted the participant’s mental health? The case study utilized three semi-structured interviews, two participant observations, video documentary review, and journaling to answer these questions. A thematic analysis of the data revealed four essential themes; 1) Development of participation, 2) Promotes …


Determinants Of Hydration In Children: The Role Of Physical Activity And Parental Dietary Habits, Hyun-Gyu Suh Aug 2018

Determinants Of Hydration In Children: The Role Of Physical Activity And Parental Dietary Habits, Hyun-Gyu Suh

Graduate Theses and Dissertations

PURPOSE: The purpose of these studies was 1) to examine the factors that influence the water intake in children and 2) to identify the optimal time window to assess hydration status that would be equivalent to 24-hour urine sample in children. METHODS: Study 1: Data for 200 parents (age:3-13y, female:62%, BMI:28.4±7.0kg∙m-2) and 200 children (age:7.5±2.9y, female:44%, BMI:17.7±3.9kg∙m-2) were recruited. Subjects recorded their fluid and food consumption on the 2-day diary, and food data were analyzed by using the Nutrition Data System for Research (NDSR) program. Physical activity levels were assessed with the International Physical Activity Questionnaire (IPAQ). All urine samples …


The Effect Of Napping On Sleep Quality And Quantity In Healthy And Concussed Collegiate Athletes, Katie Stephenson-Brown May 2018

The Effect Of Napping On Sleep Quality And Quantity In Healthy And Concussed Collegiate Athletes, Katie Stephenson-Brown

Graduate Theses and Dissertations

Clinicians are increasingly prescribing a regulated sleep schedule to athletes post injury; however, baseline sleep habits of collegiate athletes are unknown. Moreover, the connection between napping and sleep quality and quantity has not been studied in collegiate athletes. Therefore, the purpose of this study is to investigate napping behaviors and their effects on sleep quantity and quality in concussed and non-concussed collegiate athletes. In a sample of 233 non-concussed collegiate athletes, 74% (172/233) of participants reported napping. Napping was not significantly associated with sleep quantity (χ 2 (2) = .23, p = .64) or quality (χ 2 (1) = .42, …


Survey Of Hydration Knowledge And Behavior In Youth Mountain Bike Teams, Natasha Brand May 2018

Survey Of Hydration Knowledge And Behavior In Youth Mountain Bike Teams, Natasha Brand

Graduate Theses and Dissertations

Many youth sports organizations recognize the importance of educating on hydration practices and awareness, although according to recent research current hydration education is not correlating to effective practices. PURPOSE: The purpose of this study was to assess and describe the hydration knowledge and behavior of student-athletes participating in competitive junior high and high school mountain bike teams, in order to substantiate further research. METHODS: A total of 133 male and female participants, ranging from 11-18 years were surveyed on their hydration knowledge and behavior. All participants were apparently healthy and were active members of a National Interscholastic Cycling Association (NICA) …


Disordered Eating Risk And Body Image Dissatisfaction Of Division I Male And Female Cheerleaders, Christopher Blaszka May 2018

Disordered Eating Risk And Body Image Dissatisfaction Of Division I Male And Female Cheerleaders, Christopher Blaszka

Graduate Theses and Dissertations

The sport of cheerleading is growing both in the high school and college setting, however there is little research on cheerleaders specifically, both sideline and competitive. It is clear that while this sport does not benefit from being affiliated with the NCAA, the athletes are still at large risk for disordered eating and eating disorders, and are in need of more accurate screening and prevention methods. With the lack of cheerleading studies in general, there is an even larger scarcity of studies that focus on males in cheerleading. The current study aims to fill the gap in the research regarding …


Rna Sequencing In The Development Of Cancer-Cachexia, Thomas Allen Blackwell Aug 2017

Rna Sequencing In The Development Of Cancer-Cachexia, Thomas Allen Blackwell

Graduate Theses and Dissertations

Introduction: Cancer is a major public health problem in the U.S. and the world. In 2013 there were an estimated 1,660,290 new cases of cancer in the U.S. Cancer-Cachexia (CC) is a common effect of many cancers, and is directly responsible for 20-40% of cancer-related deaths. The mechanisms that control the development of CC are not well understood. Most investigations of CC focus on the post-cachectic state and do not examine the progression of the condition. The purpose of this study was to utilize RNA sequencing to analyze transcriptomic alterations throughout the progression of CC. Methods: Lewis Lung Carcinoma cells …


The Influence Of Strength-Training Exercises On The Functional Fitness In Older Adults, Susie Engle Aug 2016

The Influence Of Strength-Training Exercises On The Functional Fitness In Older Adults, Susie Engle

Graduate Theses and Dissertations

The purpose of this study was to examine the influence of strength-training exercises on the functional fitness in older adults. The original convenience sample consisted of 658 participants who attended group strength-training classes offered through the Cooperative Extension Service. The Senior Fitness Test was used to assess baseline fitness levels at the beginning and end of the 12-week strength-training program. Data was collected from 2008 to 2015. Of the 658 participants, 110 were aged 60 to 94 and presented posttest scores occurring approximately 12 weeks after pretest dates. Of the 110 subjects, 99 were female and 11 were male. The …


The Effects Of Hypohydration On Neurocognitive, Balance, Vestibular Ocular Motor Functions And Mood State, Satoshi Iida May 2016

The Effects Of Hypohydration On Neurocognitive, Balance, Vestibular Ocular Motor Functions And Mood State, Satoshi Iida

Graduate Theses and Dissertations

Inconsistent findings have been observed on the impact of hydration state on cognitive functions. The isolated effect of hypohydration on neurocognitive performance, balance, vestibular ocular motor function and mood outcomes in widely used concussion assessment tools has not been studied. The purpose of this study was to investigate how hypohydration affected the results in concussion testing batteries. A single-blind randomized crossover design was used. Thirteen healthy males (22 ± 4y, 180.9 ± 5.7cm) without history of concussion within the past six months or any condition or disease that could influence outcome measurements participated in this study. Each subject completed concussion …


A Prediction Model For Acute Core And Lower Extremity Injuries In Division 1 Collegiate Football Players, Alexandra Aline Mcdonald May 2016

A Prediction Model For Acute Core And Lower Extremity Injuries In Division 1 Collegiate Football Players, Alexandra Aline Mcdonald

Graduate Theses and Dissertations

Context: Various intrinsic factors such as high exposure, poor endurance of core muscles, previous injury, strength deficits, suboptimal neurocognitive function, and orthopedic abnormalities have been found as predictors for sprains and strains among collegiate football players. Objective: Assess the applicability of pre-participation assessments as predictors of core or lower extremity injury. Design: Cohort Study. Setting: National Collegiate Athletic Association Division I football program. Patients or Other Participants: Athletes who underwent mandatory pre-participation examinations before preseason football training over two consecutive seasons (n=225). Main Outcome Measure(s): Associations between preseason protocols and injury incidence for core and lower extremity injuries were established …


Effect Of Passive Heating On Males And Females With Elevated Arterial Stiffness, Forrest Blake Robinson May 2016

Effect Of Passive Heating On Males And Females With Elevated Arterial Stiffness, Forrest Blake Robinson

Graduate Theses and Dissertations

Context: Cardiovascular disease (CVD) is one of the leading causes of mortality in the United States, accounting for about 1 in every 4 deaths annually. Studies have shown that passive heating does have some degree of effect on arterial stiffness, but not much is known about populations with higher stiffness. Objective: To examine the independent effect of core temperature increase during passive heating on arterial stiffness. Methods: Participants visited the lab three times; one familiarization and two experimental trials. The experimental trials consisted of subjects being passively heated in an environment of 40°C / 40% relative humidity (HEAT) or normal …


The Effect Of Balance-Based Torso-Weighting On Mobility, Gait, Balance, Postural Control, And Falls Efficacy In Mobility Limited Older Adults, Jennifer L. Vincenzo May 2015

The Effect Of Balance-Based Torso-Weighting On Mobility, Gait, Balance, Postural Control, And Falls Efficacy In Mobility Limited Older Adults, Jennifer L. Vincenzo

Graduate Theses and Dissertations

Exercise is a known intervention to prevent fall risk among older adults; however, adherence is poor. Therefore, it is of interest to determine if other interventions improve function and decrease fall risk among older adults. Balance-Based Torso-Weighting (BBTW) is a non-exercise intervention that improves functional measures among adults with multiple sclerosis, yet the effectiveness of BBTW has not been assessed among older adults without progressive neurological disorders. We conducted a double-blind, randomized study to analyze the effect of BBTW on functional measures and falls efficacy among community-dwelling, mobility limited older adults after 5 days of wearing BalanceWear® for 4 hours …


The Relationship Among Ankle Function, Functional Capacity, And Body Composition To Balance In Geriatric Populations, Joseph Robert Chaney Aug 2013

The Relationship Among Ankle Function, Functional Capacity, And Body Composition To Balance In Geriatric Populations, Joseph Robert Chaney

Graduate Theses and Dissertations

The primary purpose of this research study was to identify significant relationships among measures of ankle strength, ankle range of motion, body composition, and functional capacity to balance ability in geriatric populations which may potentially assist in identifying older individuals with increased risk of falling. A battery of five test (ankle strength assessments, ankle range of motion , DXA, functional fitness, and balance) were administered to 20 participants (6 males, 14 females, mean age 69.78 ± 3.98) that had indicated to be at least 65 years of age or older and no history of falls within the previous 12 months. …


Effects Of Obesity On Thermoregulation And Cardiovascular Function During Exercise In Females, Jon David Adams Dec 2012

Effects Of Obesity On Thermoregulation And Cardiovascular Function During Exercise In Females, Jon David Adams

Graduate Theses and Dissertations

Previous research has shown that obese individuals are at greater risk for heat illnesses because of impaired thermoregulation. However, laboratory studies investigating cardiovascular and thermoregulatory function in obese individuals are difficult to interpret because of low sample sizes and methodological concerns. The purpose of this study was to determine if there are differences in thermoregulatory and cardiovascular function between obese and non-obese females. Twenty-four females, 13 obese (43.3 ± 4 .3 % fat, 77.2 ± 13.7 kg) and 11 non-obese (27.8 ± 6.0 % fat, 55.7±6.7 kg), cycled for 60 min in a warm environment (~40°C, 30% humidity) at a …


Effects Of Head Position And Head-Supported Mass On Nerve Function Of The Flexor Carpi Radialis Muscle In Healthy Individuals, Bethany Lauren Shivers Aug 2012

Effects Of Head Position And Head-Supported Mass On Nerve Function Of The Flexor Carpi Radialis Muscle In Healthy Individuals, Bethany Lauren Shivers

Graduate Theses and Dissertations

Long-term exposure to head-supported mass (HSM) has been linked with spinal degeneration including foraminal stenosis and disc deterioration. Anecdotally, HSM has also been linked to neck and arm pain and muscle atrophy, but nerve function has not been tested specifically. The combined effect of various head positions and HSM may be sufficient to compress the nerve root in aviators and Soldiers during job performance, potentially leading to short- and long-term neuromuscular effects. The Hoffmann (H) reflex, a well-established measure of nerve function, has shown to be sensitive to changes in nerve root space which occurs with different head positions. This …


The Use Of Cortisol And Hba1c As Biomarkers Of Stress In University Administrators, Jacilyn Marie Olson Aug 2012

The Use Of Cortisol And Hba1c As Biomarkers Of Stress In University Administrators, Jacilyn Marie Olson

Graduate Theses and Dissertations

PURPOSE: The purpose of this study was to explore the impact of perceived stress and cardiorespiratory fitness on cortisol and HbA1c, biomarkers of stress, in a group of select university administrators. The impact of gender on these relationships was of special concern. METHODS: University administrators with job titles of Chancellor, Provost, Vice Chancellors and Vice Provosts of the university, and Deans and Associate Deans at the college level were recruited. Twenty-five administrators (15 males and 10 females) agreed to participate and completed a battery of assessments that included completion of the University Administrative Concerns Questionnaire, a finger-stick blood test for …


Athletic Training Students' Ability To Identify Scapular Dyskinesis, Priscilla M. Dwelly Aug 2011

Athletic Training Students' Ability To Identify Scapular Dyskinesis, Priscilla M. Dwelly

Graduate Theses and Dissertations

Scapular dyskinesis refers to abnormal movement patterns of the scapula, which have been associated with injury. Previous investigations have validated the scapular dyskinesis test as a visual assessment method using physicians, physical therapists, and certified athletic trainers. Through educational programs, athletic training students should be taught what scapular dyskinesis is and how to identify it. Therefore, the purpose of this investigation was to (a) evaluate entry-level graduate athletic training students' ability to identify scapular dyskinesis, (b) assess their reliability, and (c) determine if they were able to correctly identify the muscles involved in rehabilitating an individual with scapular dyskinesis. Follow-up …


The Effects Of A Lumbopelvic Hip Complex Conditioning Program On Dynamic Knee Valgus In Female Tennis Players, Katelyn Marie Roling May 2011

The Effects Of A Lumbopelvic Hip Complex Conditioning Program On Dynamic Knee Valgus In Female Tennis Players, Katelyn Marie Roling

Graduate Theses and Dissertations

Female athletes have a four-to-six times greater risk of sustaining a lower extremity injury than their male counterparts (Hewett, 2000). One explanation for the discrepancy in injury rates is increased dynamic knee valgus angles caused by neuromuscular imbalances of the lumbopelvic hip complex (LPHC). The purpose of this study was to determine if implementing a LPHC conditioning program improved neuromuscular deficiencies. Seven female collegiate tennis players competitive at the NCAA Division I level volunteered for the study (19.7 + .95 years, 167.3 + 7.4 cm, and 60.72 kg + 6.71 kg). The subjects participated in a 16 week LPHC conditioning …