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Full-Text Articles in Medicine and Health Sciences
Social Connectedness, Social Support And The Health Of Older Adults: A Comparison Of Immigrant And Native-Born Canadians, Natalie Iciaszczyk
Social Connectedness, Social Support And The Health Of Older Adults: A Comparison Of Immigrant And Native-Born Canadians, Natalie Iciaszczyk
Electronic Thesis and Dissertation Repository
Considerable research exists on the influence of social relationships for health in old age. However, few studies have compared the associations of social connectedness and social support with the health of older adults. Using data from the CCHS-Healthy Aging, this study examines how these constructs are related to the self-reported health status of immigrant and native-born adults aged 65+. Results show that social connectedness and social support are differently associated with health in later life; whereas connectedness is linked to better health, social support is negatively related with health once levels of social connectedness are considered. Furthermore, these associations hold …
Preliminary Economic Evaluation Of Brentuximab Vedotin In Relapsed And Refractory Hodgkin Lymphoma: An "Early Look" Model Based On Phase Ii Results, Vusal Babashov
Electronic Thesis and Dissertation Repository
We conducted a cost-effectiveness analysis of brentuximab vedotin for the treatment of relapsed and refractory Hodgkin Lymphoma (HL) from health care system perspective in Canada. We developed a Markov decision analytical model to simulate lifetime costs and benefits and parameterized the model using brentuximab phase II clinical trial and cd-link data which is a linked datasets of cancer registry with administrative databases of Ontario, Canada. In the base case scenario, brentuximab treatment led to an increase of 0.352 Quality Adjusted Life Years (QALYs) per person and $108,500 per person, which resulted in incremental cost effectiveness ratio (ICER) of $308,532 per …