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Increasing Oral Health In A Midwest Elementary School: Quality Improvement Project, Dee Young May 2024

Increasing Oral Health In A Midwest Elementary School: Quality Improvement Project, Dee Young

Doctor of Nursing Practice Projects

Marginalized communities experience barriers to accessing oral healthcare in the United States (US). Due to this, many children are left to use the emergency department (ED) for dental care. The purpose of this Doctor of Nursing Practice (DNP) project was to improve oral health services access in children at one suburban Midwest elementary school. The objectives of this project were: a) to improve the efficiency of students registering in Fall 2023 to access available oral health exam services, b) to increase the number of students who receive an oral health exam compared to the number in the previous school year. …


Establishing An Objective, Quantifiable Method For Detecting Erosive Tooth Wear, Camille Kita May 2024

Establishing An Objective, Quantifiable Method For Detecting Erosive Tooth Wear, Camille Kita

Biological Sciences Undergraduate Honors Theses

This study aims to monitor and evaluate erosive tooth wear (ETW) by measurement of enamel surface thickness and texture in a clinical setting. The objective approach is fundamentally different from the standard subjective visual assessment that professionals in the dental field using the Basic Erosive Wear Evaluation (BEWE) method.

Twenty-nine hyposalivation and three control subjects were used in this longitudinal study, for a total of 597 samples (only 577 teeth were eligible for surface texture analysis) evaluated in a longitudinal study including both baseline and 12 month follow up surfaces. Each participant’s buccal surface of the tooth was first analyzed …


Mathematical Modeling For Dental Decay Prevention In Children And Adolescents, Mahdiyeh Soltaninejad Apr 2024

Mathematical Modeling For Dental Decay Prevention In Children And Adolescents, Mahdiyeh Soltaninejad

Dissertations

The high prevalence of dental caries among children and adolescents, especially those from lower socio-economic backgrounds, is a significant nationwide health concern. Early prevention, such as dental sealants and fluoride varnish (FV), is essential, but access to this care remains limited and disparate. In this research, a national dataset is utilized to assess sealants' reach and effectiveness in preventing tooth decay, particularly focusing on 2nd molars that emerge during early adolescence, a current gap in the knowledge base. FV is recommended to be delivered during medical well-child visits to children who are not seeing a dentist. Challenges and facilitators in …


Implant Overdenture Abutment Loosening Under Hyperbaric Conditions, Zana Jamal Al-Saloum Jan 2024

Implant Overdenture Abutment Loosening Under Hyperbaric Conditions, Zana Jamal Al-Saloum

Graduate Theses, Dissertations, and Problem Reports

Objectives: To investigate the effect of various hyperbaric air pressures on the loosening of LOCATOR® (ZEST Anchors, LLC, Escondido, CA USA) overdenture abutments.

The pressure conditions tested are meant to simulate scuba diving conditions in edentulous patients that are restored with implant-retained tissue-supported overdentures. Another sub-goal of this study is to determine whether or not there is a difference in LOCATOR® loosening when the sample is exposed to six cycles/dives as opposed to one cycle/dive.

Methods: 36 ZimVie Tapered Screw Vent Implants with a 3.5mm diameter implant platform, and a 2.5mm diameter (and 1.5mm deep) internal hexagon were …


The Creation Of An Innovative Oral Health Assessment Survey, Purna Patel May 2023

The Creation Of An Innovative Oral Health Assessment Survey, Purna Patel

Electronic Theses, Projects, and Dissertations

Background Oral health is an important factor to maintain overall health and well-being, such as students’ knowledge, attitude, and practice. Currently, there is a limited amount of research related to oral health awareness in college students.

Objective The purpose of the study was to define the importance of oral health and investigate college students’ understanding related to oral health. Moreover, research shows how students are protecting their oral hygiene.

Results: The outcomes revealed the college student's awareness and understanding of oral health. According to the survey questions, students believe that dental health is a significant aspect of overall health management. …


Enhancing Dental Aligners With Direct 3d Printing Manufacturing, Erin Clark, Lauren Ickes, Tyler Madison Jan 2023

Enhancing Dental Aligners With Direct 3d Printing Manufacturing, Erin Clark, Lauren Ickes, Tyler Madison

Williams Honors College, Honors Research Projects

Replacement of thermoforming with direct 3d printed aligners, molding appliances for dental and alveolar movement. Currently the process involved requires 3d printing models and plastic thermoforming, trimming and polishing to fabricate the end product. If possible a product that could be 3d printed that had stress retention, crack resistance, and stain resistance properties delivered in thickness between .030 and .040 inches.


Quantification Of Dental Fissures Through Occlusal Topography Analysis, Duru Erkan May 2022

Quantification Of Dental Fissures Through Occlusal Topography Analysis, Duru Erkan

Biological Sciences Undergraduate Honors Theses

Narrow, deep, and elaborate dental fissures are widely believed to increase the predisposition of enamel to develop carious lesions as these surfaces are thought to be ideal for cariogenic bacteria to adhere to. Therefore, dentists prescribe sealants as a preventative measure for patients with such fissures to avoid tooth decay. Yet to date, there is no objective data supporting the notion that fissure morphology actually affects caries susceptibility, nor is there a quantifiable, clinically practical method to characterize fissure patterns expected to increase risk of caries disease.

In this study, three new methods to quantitatively characterize fissure pattern in mandibular …


Association Among Anterior Maxillary Dental Arch Form, Alveolar Bone Thickness And Sagittal Root Position Of Maxillary Central Incisor : A Cone Beam Computed Tomography Analysis, Suttikiat Somvasoontra Jan 2022

Association Among Anterior Maxillary Dental Arch Form, Alveolar Bone Thickness And Sagittal Root Position Of Maxillary Central Incisor : A Cone Beam Computed Tomography Analysis, Suttikiat Somvasoontra

Chulalongkorn University Theses and Dissertations (Chula ETD)

Purpose: This study evaluated the association among the dental arch form, age-sex groups, and sagittal root position regarding alveolar bone thickness in the maxillary central incisor using cone-beam computed tomography (CBCT) images. Materials and Methods: CBCT images of 280 patients were categorized based on the dental arch form and age-sex groups. Five hundred and sixty sagittal CBCT images of the maxillary central incisors were examined to measure the labial and palatal bone thickness at the root apex level, at the mid-root level and 3 mm apically from cemento-enamel junction, with SRP classification. Chi-square, Kruskal-Wallis test, and multiple linear regression were …


Comparison Of Volumetric Changes At Implant Connector Among Three Different Types Of Abutment After Cyclic Loading, Piyawan Jirayusakamol Jan 2022

Comparison Of Volumetric Changes At Implant Connector Among Three Different Types Of Abutment After Cyclic Loading, Piyawan Jirayusakamol

Chulalongkorn University Theses and Dissertations (Chula ETD)

The aim of this study was to compare the volumetric change of dental implant among three different types of abutments after cyclic loading.Thirty dental implants (4.1x10 mm., Straumann®) were used .All of them were inserted in acrylic resin block with usual surgical protocol to gain primary stability and be able to retrieve for volumetric measurement later. Ten of each dental implant connected with Titanium abutment (Group1: Variobase abutment Straumann®), Gold abutment (Group2: UCLA abutment Straumann®) and Zirconia abutment (Group 3: Care abutment Straumann®) consecutively. Then all specimen was submitted to cyclic loading (1x106 cycles, axial load, 100N, 15 Hz) at …


The Effect Of Crowding On The Accuracy Of 3d Printed Aligners, Tonya Spangler Jan 2022

The Effect Of Crowding On The Accuracy Of 3d Printed Aligners, Tonya Spangler

Theses and Dissertations

Purpose: To evaluate the accuracy of three-dimensionally (3D) printed aligners compared to conventional vacuum-formed thermoplastic aligners with varying levels of dental crowding.

Methods: Digital intraoral scans of 10 different cases were assigned to their respective groups (n=10, each, 30 total) as follows: no crowding (control), moderate crowding, and severe crowding. Using 3Shape software, digital aligner samples were created in standard tessellation language (STL) file format and randomly 3D printed. The same STL files of each case were also sent to a dental laboratory for the fabrication of vacuum-formed samples, which is the current technology used for manufacturing aligners. The intaglio …


Catechol-Containing Copolymers As An Active Ingredient For Denture Adhesives, Vincent Ying Wun Kong Apr 2021

Catechol-Containing Copolymers As An Active Ingredient For Denture Adhesives, Vincent Ying Wun Kong

Electronic Thesis and Dissertation Repository

Moisture inside the mouth adds challenge to making denture adhesives formulations. Some formulations have zinc to enhance adhesion on wet skin despite knowing the health hazards. Inspired by mussel foot proteins’ catechol unit’s strong underwater adhesion, nine catechol-containing copolymers (P1A-P3C) were synthesized by free radical polymerization of 3,4-dimethoxystyrene (3,4- DMS) with different styrene derivatives followed by deprotection. P1A-P3C were used to make Fn(P)-C-PBS denture adhesive formulations which had suitable shear stresses around ≥ 5 kPa satisfying ISO 10873. In-situ NMR studies of free radical polymerization of 3,4 - DMS and styrene derivatives allowed computation of their reactivity ratios showing all …


A Critical Review And Finite Element Study Of Structural Relaxation In Veneered 3y-Tzp Dental Structures, Prashant S. Shelar Feb 2021

A Critical Review And Finite Element Study Of Structural Relaxation In Veneered 3y-Tzp Dental Structures, Prashant S. Shelar

Electronic Thesis and Dissertation Repository

Yttria stabilized Tetragonal Zirconia Polycrystal (3Y-TZP) materials veneered with porcelain are preferred for clinical practice due to their bio-functionality, biocompatibility, and affordability. However, these materials are often subjected to premature clinical failures due to combination of subsurface flaws and tensile stresses within porcelains. This work focuses on performing a critical literature review and evaluating veneer characteristics, i.e. structural relaxation, to form a suitable explanation for the development of subsurface stresses. User material subroutines, UEXPAN and UTRS are developed, validated and integrated in ABAQUS finite element solver. With the use of validated models, it is shown that faster cooling rates and …


The Relative Occlusal Force Of Natural Tooth Adjacent To Distal Extension Implant Support Fixed Prosthesis Using T-Scan Analysis : A Cross Sectional Study, Chin Purintarapiban Jan 2021

The Relative Occlusal Force Of Natural Tooth Adjacent To Distal Extension Implant Support Fixed Prosthesis Using T-Scan Analysis : A Cross Sectional Study, Chin Purintarapiban

Chulalongkorn University Theses and Dissertations (Chula ETD)

Objective: This cross-sectional study aimed to compare the relative occlusal force between implant in the distal end and tooth adjacent to implant in maximum intercuspation. Methodology: Patients with implant restoration replacing teeth in free end space adjacent to natural tooth were recalled. The occlusion is examined as shim stock passes through the occluded tooth in heavy or light bites. The heavy bite or a light bite with shim stock that cannot pull through is HB1 or LB1. If the shim stock can pull through it is considered HB0 or LB0. The implant is classified into 3 groups, HB1LB0, HB1LB1, and …


Accuracy Comparison Of Dental Implants Obtained By Dynamic Cais In All-On-4 Edentulous Area Among Different Types Of Bone Density: An In Vitro Study, Jutasinee Pornpolsarun Jan 2021

Accuracy Comparison Of Dental Implants Obtained By Dynamic Cais In All-On-4 Edentulous Area Among Different Types Of Bone Density: An In Vitro Study, Jutasinee Pornpolsarun

Chulalongkorn University Theses and Dissertations (Chula ETD)

Background: Determination of available bone is particularly important in implant placement quality of bone can affect the accuracy implant placement. Currently, Dynamic navigation system illustrated the improvement of implant accuracy, The accuracy of implant placement using computer-assisted implant placement system (CAIS) is unknown. As a result, the goal of this study was to see how bone density affected implant placement accuracy with Dynamic CAIS. Purpose: To determine the effect of different bone density in the accuracy of implant placement using dynamic navigation system Materials and Methods: The study's overall design includes a single doctor planning each implant using a CBCT …


A Comparison Of Implant Stability Between Two Dental Implant Designusing Two Different Stability Measuring Technique, Chanikarn Chaksupa Jan 2021

A Comparison Of Implant Stability Between Two Dental Implant Designusing Two Different Stability Measuring Technique, Chanikarn Chaksupa

Chulalongkorn University Theses and Dissertations (Chula ETD)

Objective To investigate the primary stability of aggressive thread design implant comparing to nonaggressive thread design implant and to evaluate the correlation between ISQ values and IST values. Materials and methods 96 implants were used in this study. 48 BLT Straumann® and 48 BLX Straumann® were used. All implants were digitally planned and placed in 3D printed model using computer assisted guided surgery. The edentulous area at models were packed with randomized pattern of four different kinds of polyurethane blocks to replicate mixed cancellous bone. Postoperative implant stability measurement was performed immediately after implant insertion. Implant stability was measured by …


A Comparison Of Implant Stability Between Two Implant Systems Using Guided Surgery In Inexperienced Surgeons, Pinmuk Supachaiyakit Jan 2021

A Comparison Of Implant Stability Between Two Implant Systems Using Guided Surgery In Inexperienced Surgeons, Pinmuk Supachaiyakit

Chulalongkorn University Theses and Dissertations (Chula ETD)

Aim: To investigate the implant stability in relation to two different implant designs, a cylindrical shaped single threaded design (CS/ST) and a tapered shaped double threaded design (TS/DT) using RFA over the first 8 weeks. Materials and Methods: 28 implants were randomly allocated into two groups and were placed as single tooth implant in the posterior arch. CBCT scan was used to determine the bone density and the implants were placed with guided surgical template by inexperienced surgeons which were prepared with the same implant planning software. The implant stability was measured using the RFA over the first 8 weeks …


Clinical Accuracy Between Planned And Placed Posterior Implant Position Of Two Static Implant Planning Software Programs In Inexperienced Operators, Wanwanat Singthong Jan 2021

Clinical Accuracy Between Planned And Placed Posterior Implant Position Of Two Static Implant Planning Software Programs In Inexperienced Operators, Wanwanat Singthong

Chulalongkorn University Theses and Dissertations (Chula ETD)

Objective: This study aimed to evaluate and examine the difference in posterior implant positioning between the planned and placed positions when inexperienced operators used two static implant planning software packages following a fully guided implant surgery protocol in the clinical field. Materials and methods: Twenty-four patients who needed single posterior implant placement were randomly divided into two groups based on the used implant planning software (group 1, coDiagnostiX, n=12; group 2, Implant Studio, n=12). The dataset of the placed implant position, generated from digitizing the implant impression, was superimposed on the planned implant position. The number of horizontal, angular, and …


Accuracy Of Digital Impressions At Varying Implant Depths: An In-Vitro Study, Vivia Sequeira Jan 2021

Accuracy Of Digital Impressions At Varying Implant Depths: An In-Vitro Study, Vivia Sequeira

Graduate Theses, Dissertations, and Problem Reports

Introduction: Implants placed at variable depths may vary the amount of visible scannable surface of a scan body. Intraoral scanner technology uses advanced optical principles to record the surface of the scan body to accurately capture the implant position.

Purpose: To investigate the effect implant placement depth has on the accuracy of digital implant impressions using an intraoral scanner.

Materials & Methods: A partially edentulous gypsum master model was fabricated to allow the positioning of a single implant analog at different depths. Four groups based on the planned implant depths of 0, 3, 6 and 7mm and corresponding visibility of …


The Effect Of Pigmentation On Latex And Non-Latex Orthodontic Elastics, Dustin Wilson Dec 2020

The Effect Of Pigmentation On Latex And Non-Latex Orthodontic Elastics, Dustin Wilson

Electronic Thesis and Dissertation Repository

Background: Intraoral Elastics have been widely used in Orthodontics for well over 100 years. Changes in material composition, manufacturing and addition of color to elastics has shown to effect force levels over time.

Aim: The purpose of the study was to determine the effect of pigmentation on force levels and their degradation over time in both Latex and Non-Latex orthodontic intraoral elastics.

Materials & Methods: Groups consisted of elastics in Latex from American Orthodontics in both natural and four different colors, American Orthodontics Non-Latex in natural, Ormco Latex in both natural and four different colors, Auradonics Latex in both natural …


Effect Of Nanofiller Coating And Loading On Facial Elastomer Physical Properties, Rahmi K. Aulia Aug 2020

Effect Of Nanofiller Coating And Loading On Facial Elastomer Physical Properties, Rahmi K. Aulia

Theses & Dissertations

Current materials used for facial prostheses are far from being desirable, and improved properties with “skin-like” feel are needed. This study evaluates property changes induced by sequential additions of uncoated and hydrophobic-coated nano-SiO2 to polydimethylsiloxane (PDMS) and compares them with those measured for conventional submicron SiO2-filled materials. Each filler type was sequentially added to vinyl-terminated PDMS at 0%, 0.5%, 5%, 10%, and 15% by weight. Tensile, tear, Durometer hardness, translucency and viscoelastic properties were evaluated, with hardness and translucency also evaluated following 3000 hours of outdoor weathering. Results demonstrated that 15% coated nano-SiO2-filled PDMS materials …


Metal Additive Manufacturing For Fixed Dental Prostheses, Mai El Najjar Jun 2020

Metal Additive Manufacturing For Fixed Dental Prostheses, Mai El Najjar

Electronic Thesis and Dissertation Repository

The use of additive manufacturing (AM) in dentistry has gained momentum in recent years. However, high initial costs and uncertainty surrounding the quality of AM products are considered barriers to their use. This research compared dental substructures fabricated by AM versus conventional casting and milling.

Cobalt-chromium alloy rectangular bars and three-unit bridge substructures were fabricated by AM, casting or milling. Bars manufactured by AM exhibited superior flexural strength, shear bond strength of porcelain coating, and Vickers hardness. Bridge substructures fabricated by AM showed similar flexural stiffness to cast, similar flexural loads at failure to milled and cast, and overall accuracy …


The Influence Of Fatigue Load To Various Adhesive Resin Luting Agents In A Zirconia-Reinforced Lithium Silicate Ceramic Bonded To Dentin, Ratikorn Watananiyom Jan 2020

The Influence Of Fatigue Load To Various Adhesive Resin Luting Agents In A Zirconia-Reinforced Lithium Silicate Ceramic Bonded To Dentin, Ratikorn Watananiyom

Chulalongkorn University Theses and Dissertations (Chula ETD)

Purpose. To examine fatigue failure load value of etch-and-rinse and self-adhesive luting systems used to bond ZLS to dentin. Moreover, this study seeks to evaluate whether the application of unfilled resin on silanated ceramic intaglio surface could improve fatigue failure load value. Methods. Vita Suprinity (VS, Vita Zahnfabrik) blocks were sectioned into cylindrical shape (5 mm in diameter and 1.5 mm in height). All VS were crystallized, and bonded surfaces were treated as followed: Heliobond (HB, Ivoclar Vivadent) application after silanization and non-application of HB. Each VS was cemented to each flat occlusal dentin surface of extracted human molar, following …


The Stains Of Various Lipsticks On Maxillary Anterior Ceramic Veneers, Ratirat Chotipanvidhayakul Jan 2020

The Stains Of Various Lipsticks On Maxillary Anterior Ceramic Veneers, Ratirat Chotipanvidhayakul

Chulalongkorn University Theses and Dissertations (Chula ETD)

This clinical study aims to determine differences in lipstick stains between ceramic veneers and natural teeth. Types of lipsticks affected lipstick stains on ceramic veneers and natural teeth were also investigated. A total of 30 patients were divided into two groups: ceramic-veneer (CV) group and natural-teeth (NT) group with 15 patients in each group. Seven lipstick types: Gloss & Balm, Gloss & Sheer, Cream, Liquid matte, Matte & Frost, Satin, and Matte were applied on patients’ lips. Six labial surfaces of maxillary anterior teeth were evaluated for the frequency of lipstick staining with each type of lipstick. Thus, 90 maxillary …


Effect Of Desensitizing Toothpaste Containing Calcium Sodium Phosphosilicate On Microtensile Bond Strength Of Adhesive Systems, Warin Sittiwaitayaporn Jan 2020

Effect Of Desensitizing Toothpaste Containing Calcium Sodium Phosphosilicate On Microtensile Bond Strength Of Adhesive Systems, Warin Sittiwaitayaporn

Chulalongkorn University Theses and Dissertations (Chula ETD)

Purpose: To evaluate the effect of a desensitizing toothpaste, containing calcium sodium phosphosilicate, on microtensile bond strength of adhesive systems treated to dentine. Methods: Fifty-two human third molars were embedded into acrylic resin, and cut to expose flat dentin surface. The specimens were randomly divided into two groups, 1) no brushing, and 2) brushing with Sensodyne Repair&Protect (GSK, London, UK) for 10,000 cycles with a V-8 cross brushing machine (Sabri Dental Enterprise, Inc., USA). Subsequently, both groups were divided into three groups for resin composite build-up using different adhesive agents (OptiBond FL® (Kerr, Orange, CA, USA), Clearfil SE Bond® (Kuraray …


Exploring The Use Of Pulsed Erbium Lasers To Retrieve A Zirconia Crown From A Zirconia Implant Abutment, Ahmed Elkharashi Jan 2020

Exploring The Use Of Pulsed Erbium Lasers To Retrieve A Zirconia Crown From A Zirconia Implant Abutment, Ahmed Elkharashi

Theses and Dissertations

Removal of zirconia crowns, commonly used as cement-retained implant fixed restorations, can be challenging. Conventional methods of crown removal are time consuming and often leave irreparable damage to the crown, which can be costly to patients and practitioners. This research explored the use of two different types of pulsed erbium lasers, erbium-doped yttrium aluminum garnet laser (Er:YAG) and erbium, chromium-doped yttrium, scandium, gallium and garnet (Er,Cr:YSGG), as non-invasive tools to retrieve cemented zirconia crowns from zirconia implant abutments. Times needed to remove the crowns were recorded and analyzed using ANOVA (��=0.05). No statistical differences between the debond times of each …


An Investigation Into The History, Science, And Future Of Dental Filling Materials, Natalia Kaczor Jan 2020

An Investigation Into The History, Science, And Future Of Dental Filling Materials, Natalia Kaczor

Honors Theses

No abstract provided.


The Visual And Spectrophotometric Effect Of External Bleaching On Omnichroma Resin Composite And Natural Teeth, Michael Brian Evans Jan 2020

The Visual And Spectrophotometric Effect Of External Bleaching On Omnichroma Resin Composite And Natural Teeth, Michael Brian Evans

Graduate Theses, Dissertations, and Problem Reports

Objective: To determine the visual and spectrophotometric effect external tooth bleaching has on natural tooth structure and OMNiCHROMA composite at various number of treatments. Variables were compared to determine if there is a detectable difference between the composite and the tooth before and after bleaching.

Methods: Preparation and restoration of 25 previously extracted teeth was completed. OMNiCHROMA composite was used. Each tooth was measured visually with a VITA shade guide and a colorimeter. Measurements were recorded before bleaching, after 5 and 10 treatments. Statistical analysis was completed and ΔE values between the composite and tooth were compared between the 3 …


The Effectiveness Of Resin-Modified Glass Ionomer Varnish In Preventing White Spot Lesions During Fixed Appliance Orthodontic Therapy: An In Vitro Study, Bradley Herman Dec 2019

The Effectiveness Of Resin-Modified Glass Ionomer Varnish In Preventing White Spot Lesions During Fixed Appliance Orthodontic Therapy: An In Vitro Study, Bradley Herman

Theses & Dissertations

The purpose of this investigation was to evaluate the efficacy of a glass ionomer varnish in preventing demineralization of enamel adjacent to and some distance away from an orthodontic bracket. Forty extracted human molars were divided into four different treatment groups (varnish in distilled water, varnish in acetic acid, enamel in acetic acid, and enamel in distilled water). Two 3 x 3 mm graphite windows were drawn on the tooth, one adjacent to the bracket and one 3 mm away from the first window, indicating the scanning area. Varnish was applied to the teeth in the varnish groups and all …


Marginal Staining Between Pressed Lithium Disilicate Ceramic Crowns And Direct Restorative Materials By Various Fluids : A Microleakage Study., Sarah Ann Jestel May 2019

Marginal Staining Between Pressed Lithium Disilicate Ceramic Crowns And Direct Restorative Materials By Various Fluids : A Microleakage Study., Sarah Ann Jestel

Electronic Theses and Dissertations

When treating patients with existing restorations in which indirect restoration placement is indicated and crown lengthening surgery is contraindicated, dentists may choose to finish the crown margin on an existing restoration. The interface between the two dental restorations (resin composite and ceramic crown) may be more susceptible to microleakage and fluid staining, reducing restoration longevity. In this study, 80 extracted molars received indirect restoration margins finished on different direct restorative materials (resin-modified glass ionomer and conventional, flowable, and bulk fill nano-hybrid resin composite) and subjected to common staining fluids of coffee, tea, red wine, or Coca-Cola. If the clinician must …


Mass Spectrometry-Based Proteomics Analysis Of Bioactive Proteins In Emd That Modulate Adhesion Of Gingival Fibroblast To Improve Bio-Integration Of Dental Implants, David Zuanazzi Machado Jr Mar 2019

Mass Spectrometry-Based Proteomics Analysis Of Bioactive Proteins In Emd That Modulate Adhesion Of Gingival Fibroblast To Improve Bio-Integration Of Dental Implants, David Zuanazzi Machado Jr

Electronic Thesis and Dissertation Repository

Titanium implants are used in dental practice to replace damaged or lost teeth. The implant needs to integrate with the surrounding gingiva to protect it against bacterial invasion that leads to implant loss. The biointegration is dependent on the implant surface that interacts with proteins from biological fluids to modulate tissues response. Tailoring the surface with specific proteins from the enamel matrix derivative (EMD) would be beneficial to improve the implant-gingiva interface since EMD can affect various cells including gingival fibroblasts. A surface-affinity approach using three different titanium surfaces and saliva was utilized as a model in combination with tandem …