Medicine and Health Sciences Commons^™

Dental Caries In Children With Sickle Cell Disease And Its Association With The Use Of Hydroxyurea And Penicillin Prophylaxis In Dar Es Salaam, Irene Kida Minja, Evarist Mulyahela Wilson, Ferdinand M. Machibya, Agnes Jonathan, Fortunata Cornel, Paschal Ruggajo, Julie Makani, Ferdinand M. Machibya

Internal Medicine, East Africa

Purpose.

This comparative study sets out to report dental caries status among individuals with Sickle Cell Disease (HbSS) against those with sickle cell trait (HbSA) and those without the disease (HbAA) as controls. The study further assessed the impact of penicillin chemoprophylaxis and hydroxyurea use on dental caries among Sickle Cell Disease participants.

Methods.

This was a comparative cross-sectional study in which 93 children aged 30 to 60 months were recruited. There were 60 participating children who had SCD (HbSS), 17 with SCD trait (HbAS) and 16 were without SCD or SC trait (HbAA). A questionnaire was used to record …

Pediatric Oral Health: Advances And Challenges, Denise M. Claiborne

Dental Hygiene Faculty Publications

No abstract provided.

Dataset Of Antemortem Tooth Loss And Carious Lesions At Deir El-Medina, Anne Austin

UMSL Datasets

These data are from observations on antemortem tooth loss and the presence of carious lesions from the site of Deir el-Medina, Egypt. The data were collected by Anne Austin and Mélie Louys as part of the mission of the Institut Français d’Archéologie Orientale at the site during the 2012-14 and 2019-20 field seasons. These data were derived from human remains found in Theban Tombs 6, 217, 290, and 298. They are estimated to date from 1550-945 BCE. These data include macroscopic observations from 32 mandibles and 44 maxillae consisting of 485 observable teeth and 1,052 observable tooth sockets. Any mandibles …

Dataset Of Antemortem Tooth Loss And Carious Lesions At Deir El-Medina, Anne Austin

History Faculty Works

These data are from observations on antemortem tooth loss and the presence of carious lesions from the site of Deir el-Medina, Egypt. The data were collected by Anne Austin and Mélie Louys as part of the mission of the Institut Français d’Archéologie Orientale at the site during the 2012-14 and 2019-20 field seasons. These data were derived from human remains found in Theban Tombs 6, 217, 290, and 298. They are estimated to date from 1550-945 BCE. These data include macroscopic observations from 32 mandibles and 44 maxillae consisting of 485 observable teeth and 1,052 observable tooth sockets. Any mandibles …

Bonded Amalgam As A Fissure Sealant In Low-Income Setting: A Randomised Controlled Trial, Farhan Raza Khan, Samreen Liaquat, Ghazala Rafique, Syed Iqbal Azam, Arshad Hasan

Section of Dental-Oral Maxillofacial Surgery

Objectives: To compare one year retention rate of bonded amalgam sealants (BAS) with that of conventional resin-based sealant (RBS).
Methods: It was a parallel group, equivalence, randomised controlled trial done during March 2018 to December 2019 at the dental clinics of Dow University of Health Sciences, and the Jinnah Sind Medical University, Karachi, Pakistan on children aged 12-16 years, who were randomly assigned to one of the two treatment groups (BAS vs. RBS). Complete retention of the sealant at one year follow-up was labeled as success. Multi-level mixed effect logistic regression model was employed. Study was registered at www.clinicaltrials.gov # …

Type 2 Diabetes Mellitus And Oral Health Problems Cross-Sectional Study, Asmaa Ras, Eman Khalil

Dentistry

ABSTRACT In Egypt, diabetes mellitus is considered to be a foremost health issue with a major influence on the disease and the rate of death. Diabetes mellitus is a communal disorder having affiliated oral disorders that influence dental care. The purpose of this study was to study the prevalence of oral changes in diabetes type 2 in the Egyptian participants to raise awareness between diabetic patients and dental professionals. Methods: This was a cross-sectional study that was done on 200 patients who were diagnosed with diabetes mellitus type 2 at Diabetes and Endocrinology Clinic in Kasr Al Ainy, Cairo University …

Current Status Of Magnetic Resonance On Saliva For Oral And Dental Health Early Diagnosis, Anastasia Katsavochristou, Dimitrios Koumoulis

Oral Health Practice Faculty Publications

Magnetic resonance spectroscopy of biomolecules has recently gained attention for clinical diagnosis. Its combination with saliva collection and analysis can promote early disease detection and monitoring, by identifying biomarkers of specific underlying pathology or disease as detected in saliva. With this novel, non-invasive technique, certain salivary biomarkers have been linked to dental and periodontal tissues pathology, as well as to specific head and neck cancer malignancies. At present, diagnostic biomarkers are still in need for further identification (e.g., diagnosis and monitoring of Sjögren’s syndrome), and nuclear magnetic resonance spectroscopy has been found to be a promising technique to compliment the …

Get In The Zone: A Survey Of Dental Professionals' Knowledge Of Ozone Therapy, Emily Hannah

Mahurin Honors College Capstone Experience/Thesis Projects

Ozone therapy has been used in medicine for many years to treat a variety of ailments. Ozone is an unstable triatomic molecule made up of three oxygen atoms. This molecule has the ability to kill bacteria, fungi, parasites, and viruses. The researcher first was curious if there has been research done on uses of Ozone Therapy in the dental setting. After reviewing the literature there is indeed a use for Ozone Therapy to treat a host of dental problems including periodontal disease, ulcers, and carious lesions (also known as cavities). However, there are conflicting conclusions in the literature as to …

A Phase Ii Clinical Trial Of A Dental Health Education Program Delivered By Aboriginal Health Workers To Prevent Early Childhood Caries, Fiona Blinkhorn, Ngiare Brown, Ruth Freeman, Gerry Humphris, Andrew Martin, Anthony Blinkhorn

Graduate School of Medicine - Papers (Archive)

Background: Early Childhood Caries (ECC) is a widespread problem in Australian Aboriginal communities causing severe pain and sepsis. In addition dental services are difficult to access for many Aboriginal children and trying to obtain care can be stressful for the parents. The control of dental caries has been identified as a key indictor in the reduction of Indigenous disadvantage. Thus, there is a need for new approaches to prevent ECC, which reflect the cultural norms of Aboriginal communities. Methods/Design. This is a Phase II single arm trial designed to gather information on the effectiveness of a dental health education program …

Association Between Caries, Obesity And Insulin Resistance In Mexican Adolescents, Juan Pablo Loyola-Rodgriguez, Carlos Villa-Chavez, Nuria Patiño-Marin, Celia Aradillas-Garcia, Cesar Gonzalez, Esperanza De La Cruz-Mendoza

School of Dentistry Faculty Research and Publications

Aim: To determine the association among dental caries, obesity and insulin resistance in Mexican adolescents. Methods: Body Mass Index, obesity (OB) blood pressure, insulin level, insulin resistance (IR), triglycerides level, serum HDL-cholesterol (cHDL), DMFT index and salivary flow were measured. Results: Anthropometric measures showed a significant statistical difference (p < 0.05). Insulin level was 8.98 for healthy subjects, whereas for OB-IR group was 25.35, there was a statistical significant difference (p < 0.05). Triglycerides level was 88.50 for healthy subjects and 169.40 mg/dL for OB-IR; cHDL was 52.88 for healthy and 41.82 mg/dL for OB-IR group, both showed a statistically significant difference (p < 0.05). Salivary flow was 4.30 for healthy and for OB-IR group was 5.48 ml/min showed a significant statistical difference (p < 0.05). DMFT index was 3.02 for healthy and for OB-IR adolescents was 4.78, showed a significant statistical difference (p < 0.05). The caries component of DMFT index was 1.84 for healthy and was 3.52 for OB-IR adolescents, showed a significant statistical difference (p < 0.05). According to the multivariate analysis, DMFT (OR=3.10; IC95%=0.20-1.02, p=0.042) and decay (OR=3.30; IC95%=0.19-1.0, p=0.011) were associated with subjects with OB-IR. Conclusion: OB-IR Mexican adolescents showed a positive association with DMFT.

Etiology Of Oral Disease In View Of Microbial Complexity, Anne C. R. Tanner, Jacques Izard

Department of Food Science and Technology: Faculty Publications

The number of different microorganisms recognized in the oral cavity using molecular methods has more than doubled compared with the number isolated using cultural techniques. This finding necessitates a reevaluation of which species may be pathogens in dental infections. Molecular methods used to determine microbial diversity include broad range target Polymerase Chain Reaction with ‘universal primers,’ and cloning amplicons or denaturing gradient gel electrophoresis to separate DNA fragments before sequencing. These molecular methods have clarified and expanded the taxonomy of oral microbial species. Discrepancies between comprehensive molecular and cultural methods suggest that neither method alone can adequately evaluate associations of …