Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- Amphibian (1)
- Aneurysm (1)
- Antibody (1)
- Antigen (1)
- Anxiety (1)
-
- Aromatherapy (1)
- Atherosclerosis (1)
- Autodock (1)
- Autodock vina (1)
- Autoimmune (1)
- Avogadro (1)
- Batrachochytrium dendrobatidis (1)
- Batrachochytrium salamandrivorans (1)
- Bergamote (1)
- Blocking antibodies (1)
- Blocking antigens (1)
- Cancer development (1)
- Cardiomyopathy (1)
- Cardiovascular (1)
- Cave salamander (1)
- Cell Signaling (1)
- Cell Signalling (1)
- Chimerax (1)
- Chytridiomycosis (1)
- Citrus aurantium (1)
- Cultural communication (1)
- Curcumin (1)
- Cutaneous microbiome (1)
- Emerging infectious disease (1)
- Essential oil (1)
Articles 1 - 7 of 7
Full-Text Articles in Medicine and Health Sciences
Managing Tuberculosis In Refugee Populations, Roselyn Fierkens
Managing Tuberculosis In Refugee Populations, Roselyn Fierkens
Senior Honors Theses
Tuberculosis (TB) is an airborne-transmitted infectious disease, responsible for more global deaths than HIV. Multidrug-resistant strains are developing, which heightens the need for swift eradication. Current data states that 71.4% of all TB cases in the United States occur in foreign-born individuals, so populations traveling from TB endemic areas are a key target population for prevention strategies. Various screening procedures exist, but no successful standard is in place. Beyond prevention and treatment strategies, adaptations to cultural communication differences are integral to successful medical interventions. This synthesis of TB pathophysiology, treatments, risk factors, and cultural considerations is intended for use in …
Characterizing The Cutaneous Microbiome Of Eurycea Lucifuga As A Potential Defense Against Chytridiomycosis, Madeline Key
Characterizing The Cutaneous Microbiome Of Eurycea Lucifuga As A Potential Defense Against Chytridiomycosis, Madeline Key
Senior Honors Theses
Chytridiomycosis is an emerging infectious disease that is significantly reducing global amphibian populations. The disease is caused by Batrachochytrium dendrobatidis (Bd), a fungus that lethally modifies amphibian skin. Recent research has suggested that the cutaneous microbiome of individual amphibians may play a role in susceptibility to the pathogen. In this study, twelve cave salamanders (Eurycea lucifuga) were collected. Cutaneous bacteria from each salamander were isolated and identified using Sanger Sequencing. Additionally, a Bd-challenge assay was performed to determine each isolate’s antifungal activity. Results indicated many microbial isolates possessed inhibitory capabilities against Bd, which may …
The Anxiolytic Effects Of Aromatherapy On Preprocedural Anxiety: An Integrated Review, Rebekah Smith
The Anxiolytic Effects Of Aromatherapy On Preprocedural Anxiety: An Integrated Review, Rebekah Smith
Senior Honors Theses
Anxiety before procedures can negatively impact patients by increasing cortisol levels which delays wound healing and increases infection risk, increasing pain and sedation medication needs, and increasing hospitalization time. This review was conducted to find how inhaled essential oils affect pre-procedural anxiety of adults in acute care settings. Nine databases and some gray literature were searched within the past ten years, and documented using the PRISMA flow chart. Ten articles fitting the inclusion criteria were retrieved. Nine of the articles found a significant difference between the aromatherapy group and control group and pre- and post- intervention anxiety scores, and none …
Jnk And Nf-Κb Cell Signaling Pathways In Cardiovascular Disease Present Potential Targets For Curcumin Therapy, Mary Richfield
Jnk And Nf-Κb Cell Signaling Pathways In Cardiovascular Disease Present Potential Targets For Curcumin Therapy, Mary Richfield
Senior Honors Theses
Curcumin (diferuloylmethane) is a compound derived from the rhizomes of Curcumin longa that has been long used for medicinal purposes. Curcumin alleviates the pathology of cardiovascular diseases, including atherosclerosis, aneurysm, and cardiomyopathy. The mechanism of curcumin therapy is under active research. The NF-κB and JNK pathways are two that curcumin interacts with to block inflammatory processes, apoptosis, and fibrotic tissue remodeling to prevent the pathologies of cardiovascular disease. While curcumin has demonstrated powerful mediation of cardiovascular disease, its bioavailability in body tissues is limited due to the instability and hydrophobicity of its structure. Further work is underway to stabilize …
The Effects Of Mosaic Law Observance On Human Health, Emily Uhlmeyer
The Effects Of Mosaic Law Observance On Human Health, Emily Uhlmeyer
Senior Honors Theses
For the people of ancient Israel, life was guided and regulated by adherence to the law of Moses. Dietary restrictions, purification rituals, circumcision, and Sabbath observance were each critical components of this code and were meticulously detailed in the Old Testament, specifically in the Torah. Still today, dietary laws are observed and select rituals practiced by many Jews and Seventh Day Adventists. Although health protection was never the primary purpose of the law, noticeable effects on human health have been connected to its observance. Evaluation of the effects of the Levitical law on human health can be achieved by a …
A Proposed Treatment Of Mixed Connective Tissue Disease By Competitive Inhibition Of Autoantibodies, Thomas Russell
A Proposed Treatment Of Mixed Connective Tissue Disease By Competitive Inhibition Of Autoantibodies, Thomas Russell
Senior Honors Theses
Mixed Connective Tissue Disease is an autoimmune disease characterized by Raynaud’s phenomenon and arthritis among other symptoms. It is primarily caused by antibodies that target the U1-RNP 70K peptide. The treatment proposed in this paper uses competitive inhibition to prevent the binding of the anti-U1-RNP 70K antibodies with the U1-RNP 70K peptide. A method for testing the designed treatment in silico is proposed using AutoDock Vina docking software.
Investigation Of Oncogenic Ras And Endoplasmic Reticulum-Mitochondria Calcium Flux And Their Relationship In The Context Of Tumorigenesis, Emma Anderson
Senior Honors Theses
Intracellular calcium as a signaling molecule is a pervasive feature of cellular pathways, especially those that manage internal homeostasis and transitions through the cell cycle, so much so that regulated, responsive calcium flux between the endoplasmic reticulum (ER) and the mitochondria has been suggested to play a major role in cancer development. Another factor commonly implicated in tumorigenesis is RAS, an oncogene that controls signaling for many pathways that are also regulated by calcium. While both calcium and oncogenic RAS signaling are implicated in cancer development, possible links between them have yet to be determined. The identification of these links …