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Malaria: Existence Perpetuated By A Counterfeit Drug Industry, Nicholas Black Jun 2022

Malaria: Existence Perpetuated By A Counterfeit Drug Industry, Nicholas Black

Undergraduate Research Symposium

Malaria is a mosquito-borne disease that has plagued society for thousands of years. Malaria is often overlooked from the perspective of wealthier industrialized countries due to prevention efforts largely eliminating malaria from these locations. However, overlooking malaria’s continued global relevance is misinformed to the fact that nearly half the global population lives in regions at risk of malarial transmission. According to the CDC and WHO, such a high number of people at risk has subsequently led to an estimated 241 million cases and over 627 thousand deaths in 2020 alone. The purpose for the present research is to examine the …


Staph Infection: Hospitals Battle Against A Deadly Menace, Mckenzie Lamos Jun 2022

Staph Infection: Hospitals Battle Against A Deadly Menace, Mckenzie Lamos

Undergraduate Research Symposium

Staph infection is caused by the staphylococcus bacteria, which is found on the skin or within the nose of even healthy individuals. This bacteria is usually harmless, but deadly infectious diseases may arise when it enters deep within the body. Staph infection is commonly treated with antibiotics, however the methicillin-resistant Staphylococcus aureus (MRSA) strain is resistant to antibiotics which further complicates treatment. This research provides insight on preventative measures to stop and slow the spread of staph infection in hospitals, along with what is being done to limit the number of MRSA infections. The CDC and NCBI both outline strategies …


Resolving The Repression Pathway Of Virulence Gene Hila In Salmonella, Alexandra King, Lon Chubiz Phd, Brenda Pratte, Lauren Daugherty Jun 2022

Resolving The Repression Pathway Of Virulence Gene Hila In Salmonella, Alexandra King, Lon Chubiz Phd, Brenda Pratte, Lauren Daugherty

Undergraduate Research Symposium

Salmonella is a relatively abundant, virulent species of bacteria that is most known for spreading gastrointestinal diseases through food. These illnesses result in approximately 1.35 million infections, including over 25,000 hospitalizations each year, in the U.S. alone (CDC.gov). As antibiotic resistance becomes an increasingly urgent public health problem, the importance of developing alternative treatment methods is only becoming more crucial. One of the genes responsible for this virulence is known as hilA. HilA is the main transcriptional regulator of Salmonella Pathogenicity Island-1 gene (UniProt). SPI-1 plays an important role in the invasion of Salmonella into epithelial cells. The proteins encoded …