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Full-Text Articles in Medicine and Health Sciences

A Changing Epidemic And The Rise Of Opioid-Stimulant Co-Use, Saeed Ahmed, Zouina Sarfraz, Azza Sarfraz Jul 2022

A Changing Epidemic And The Rise Of Opioid-Stimulant Co-Use, Saeed Ahmed, Zouina Sarfraz, Azza Sarfraz

Department of Paediatrics and Child Health

No abstract provided.


Sex Differences In Locomotor Activity And Behavioral Sensitization In Rats Administered Fentanyl, Jessica J. Lee, Nareen Sadik, Cameron Davidson Phd, Majd Yahya, Josie Zdun, Shane Perrine Phd Jun 2022

Sex Differences In Locomotor Activity And Behavioral Sensitization In Rats Administered Fentanyl, Jessica J. Lee, Nareen Sadik, Cameron Davidson Phd, Majd Yahya, Josie Zdun, Shane Perrine Phd

Medical Student Research Symposium

Opioid overdoses have continued to increase, and women have experienced a greater rate of increase than males. Preclinical studies demonstrate marked sex differences in addiction-related behaviors, with females being more vulnerable due to a potential role of estradiol. We sought to understand how the estrous cycle, as a proxy measure of estradiol, influences sex differences in the sensitizing effects of fentanyl. In this ongoing study, we used male and female rats to investigate potential sex effects of fentanyl (20µg/kg subcutaneously) administration for 14 days and a forced abstinence period of 13 days on behavioral sensitization via locomotor activity (LMA) following …


The Increase Of Fentanyl Use In Young Adults And Its Relationship To Mental Illness, Madison Lilleberg, Madison Regel, Bashaer Abdushakour, Rosalee Allan Apr 2022

The Increase Of Fentanyl Use In Young Adults And Its Relationship To Mental Illness, Madison Lilleberg, Madison Regel, Bashaer Abdushakour, Rosalee Allan

2022 Symposium

The abuse of prescription pain medication has risen to exponential levels in the United States within the past few years, leading to overdose deaths. The opioid epidemic sparked the popularity of the use of Fentanyl due to its highly potent pain-fighting properties. What was once approved to manage pain symptoms for cancer patients is now being used by thousands of young individuals irresponsibly and poses a threat to the health of our population. It is also becoming increasingly common worldwide to find this synthetic opioid mixed with other illicit drugs.

The scope of the research focuses on studies on self-medication …