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Full-Text Articles in Medicine and Health Sciences
It’S Playoff Time – And A Reminder That Brain Health Comes First, Kenneth P. Serbin
It’S Playoff Time – And A Reminder That Brain Health Comes First, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
Creating A Christmas Memory For A Huntington’S Family, Kenneth P. Serbin
Creating A Christmas Memory For A Huntington’S Family, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
‘Alive And Well’ Captures Struggle Against Untreatable Brain Disorder, Kenneth P. Serbin
‘Alive And Well’ Captures Struggle Against Untreatable Brain Disorder, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
A Huntington’S Thanksgiving Message: Gratitude For Health And The Ability To Work, Kenneth P. Serbin
A Huntington’S Thanksgiving Message: Gratitude For Health And The Ability To Work, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
Braving Bioethical Challenges: The Importance Of Huntington's Disease, Kenneth P. Serbin
Braving Bioethical Challenges: The Importance Of Huntington's Disease, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
One Year Out Of The Terrible, Lonely Huntington’S Disease Closet, Kenneth P. Serbin
One Year Out Of The Terrible, Lonely Huntington’S Disease Closet, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
Mismatch Repair Genes Mlh1 And Mlh3 Modify Cag Instability In Huntington's Disease Mice: Genome-Wide And Candidate Approaches, Ricardo Mouro Pinto, Ella Dragileva, Andrew Kirby, Alejandro Lloret, Edith Lopez, Jason St. Claire, Gagan B. Panigrahi, Caixia Hou, Kim Holloway, Tammy Gillis, Jolene R. Guide, Paula E. Cohen, Guo-Min Li, Christopher E. Pearson, Mark J. Daly, Vanessa C. Wheeler
Mismatch Repair Genes Mlh1 And Mlh3 Modify Cag Instability In Huntington's Disease Mice: Genome-Wide And Candidate Approaches, Ricardo Mouro Pinto, Ella Dragileva, Andrew Kirby, Alejandro Lloret, Edith Lopez, Jason St. Claire, Gagan B. Panigrahi, Caixia Hou, Kim Holloway, Tammy Gillis, Jolene R. Guide, Paula E. Cohen, Guo-Min Li, Christopher E. Pearson, Mark J. Daly, Vanessa C. Wheeler
Toxicology and Cancer Biology Faculty Publications
The Huntington's disease gene (HTT) CAG repeat mutation undergoes somatic expansion that correlates with pathogenesis. Modifiers of somatic expansion may therefore provide routes for therapies targeting the underlying mutation, an approach that is likely applicable to other trinucleotide repeat diseases. Huntington's disease Hdh(Q111) mice exhibit higher levels of somatic HTT CAG expansion on a C57BL/6 genetic background (B6.Hdh(Q111) ) than on a 129 background (129.Hdh(Q111) ). Linkage mapping in (B6x129).Hdh(Q111) F2 intercross animals identified a single quantitative trait locus underlying the strain-specific difference in expansion in the striatum, implicating mismatch repair (MMR) gene Mlh1 as the most likely candidate modifier. …
‘Tired Of Waiting,’ Huntington’S Disease Families Engrossed In Efforts To Conduct Clinical Trials, Kenneth P. Serbin
‘Tired Of Waiting,’ Huntington’S Disease Families Engrossed In Efforts To Conduct Clinical Trials, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
The End Of Fear And Exclusion: Informing My Health Insurance Plan About The Risk Of Huntington's Disease, Kenneth P. Serbin
The End Of Fear And Exclusion: Informing My Health Insurance Plan About The Risk Of Huntington's Disease, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
Hope, Cutting-Edge Science, And Poignant Moments At The World Congress On Huntington's Disease, Kenneth P. Serbin
Hope, Cutting-Edge Science, And Poignant Moments At The World Congress On Huntington's Disease, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
Reaching Out To The ‘Hd Family’ At The World Congress On Huntington's Disease, Kenneth P. Serbin
Reaching Out To The ‘Hd Family’ At The World Congress On Huntington's Disease, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
Heading To Rio For The 2013 World Congress On Huntington's Disease, Kenneth P. Serbin
Heading To Rio For The 2013 World Congress On Huntington's Disease, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
Advocacy Meets Science And Medicine: Personal Enrichment And A Coping Mechanism For Huntington's Disease, Kenneth P. Serbin
Advocacy Meets Science And Medicine: Personal Enrichment And A Coping Mechanism For Huntington's Disease, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
‘Predicting’ Huntington’S Disease In The Heartland, Kenneth P. Serbin
‘Predicting’ Huntington’S Disease In The Heartland, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
A Gene-Positive Dad’S Reflections On Huntington’S Disease, Parenthood, And The Fragility Of Life, Kenneth P. Serbin
A Gene-Positive Dad’S Reflections On Huntington’S Disease, Parenthood, And The Fragility Of Life, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
Going With The Flow Of Time, Kenneth P. Serbin
Going With The Flow Of Time, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
Fighting For The Option To Care For Huntington’S Disease Patients At Home, Kenneth P. Serbin
Fighting For The Option To Care For Huntington’S Disease Patients At Home, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
Strangling Of Patient In Nursing Home A Shuddering Reminder Of Subpar Care For Huntington's Disease, Kenneth P. Serbin
Strangling Of Patient In Nursing Home A Shuddering Reminder Of Subpar Care For Huntington's Disease, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
Do We Need To Shock The World To Strengthen The Huntington's Disease Cause, Kenneth P. Serbin
Do We Need To Shock The World To Strengthen The Huntington's Disease Cause, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
Memories Of Genetic Testing: From My Mom To Angelina Jolie, Kenneth P. Serbin
Memories Of Genetic Testing: From My Mom To Angelina Jolie, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
A Key New Ally In The Search For Huntington’S Disease Treatments, Kenneth P. Serbin
A Key New Ally In The Search For Huntington’S Disease Treatments, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
Feeling The Hope, Kenneth P. Serbin
Feeling The Hope, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
Quickening The Pace Towards A Huntington’S Disease Gene-Silencing Clinical Trials: Pharma Giant Roche, Isis Enter Partnership, Kenneth P. Serbin
Quickening The Pace Towards A Huntington’S Disease Gene-Silencing Clinical Trials: Pharma Giant Roche, Isis Enter Partnership, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
Brazil’S Big Place On The Huntington’S Disease Map, Kenneth P. Serbin
Brazil’S Big Place On The Huntington’S Disease Map, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
Big Decisions While Facing The Threat Of Huntington's Disease, Kenneth P. Serbin
Big Decisions While Facing The Threat Of Huntington's Disease, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
The Brain Activity Map Project: Short- And Long-Term Prospects For Huntington's Disease Research, Kenneth P. Serbin
The Brain Activity Map Project: Short- And Long-Term Prospects For Huntington's Disease Research, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
The Return Of The Huntington’S Whirlwind, Kenneth P. Serbin
The Return Of The Huntington’S Whirlwind, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
Pope Benedict Xvi’S Resignation: A Witness To Aging, A Signal For A New Bioethics, Kenneth P. Serbin
Pope Benedict Xvi’S Resignation: A Witness To Aging, A Signal For A New Bioethics, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
‘No Marine Deserted On The Battlefield’: Two Surviving Spouses Join Forces To Speed The Defeat Of Huntington's Disease, Kenneth P. Serbin
‘No Marine Deserted On The Battlefield’: Two Surviving Spouses Join Forces To Speed The Defeat Of Huntington's Disease, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.
Junior Seau, Super Sunday, And Our Most Important Natural Resource, Kenneth P. Serbin
Junior Seau, Super Sunday, And Our Most Important Natural Resource, Kenneth P. Serbin
At Risk for Huntington's Disease
No abstract provided.