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Medicine and Health Sciences Commons

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2013

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Full-Text Articles in Medicine and Health Sciences

Temporal-Spatial Heterogeneity In Animal-Environment Contact: Implications For The Exposure And Transmission Of Pathogens, Shi Chen, Michael W. Sanderson, Brad J. White, David E. Armine, Cristina Lanzas Nov 2013

Temporal-Spatial Heterogeneity In Animal-Environment Contact: Implications For The Exposure And Transmission Of Pathogens, Shi Chen, Michael W. Sanderson, Brad J. White, David E. Armine, Cristina Lanzas

Faculty Publications and Other Works -- Biomedical and Diagnostic Sciences

Contact structure, a critical driver of infectious disease transmission, is not completely understood and characterized for environmentally transmitted pathogens. In this study, we assessed the effects of temporal and spatial heterogeneity in animal contact structures on the dynamics of environmentally transmitted pathogens. We used real-time animal position data to describe contact between animals and specific environmental areas used for feeding and watering calves. The generated contact structure varied across days and among animals. We integrated animal and environmental heterogeneity into an agent-based simulation model for Escherichia coli O157 environmental transmission in cattle to simulate four different scenarios with different environmental …