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- ERP (2)
- Adolescence drug treatment (1)
- Adolescence; Diffusion tensor imaging; Sex differences; Tract based spatial statistics; White matter development (1)
- Attention (1)
- Brain derived neurotrophic factor (1)
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- Children (1)
- Event-related potentials; ERP; topographical ERP analysis; speed of speech processing; specific language impairment; grammatical treatment; grammar (1)
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Articles 1 - 8 of 8
Full-Text Articles in Medicine and Health Sciences
Prenatal Development: Annotated Bibliography, Victoria J. Molfese, Amanda Prokasky, Kathleen Moritz Rudasill, Ibrahim H. Acar, Xiaoqing Tu, Kate Sirota, Brian Keiser
Prenatal Development: Annotated Bibliography, Victoria J. Molfese, Amanda Prokasky, Kathleen Moritz Rudasill, Ibrahim H. Acar, Xiaoqing Tu, Kate Sirota, Brian Keiser
Department of Child, Youth, and Family Studies: Faculty Publications
For decades, researchers have investigated how events in the prenatal period impact women and their infants. These studies, particularly by researchers in the medical, neuroscience, and behavioral science fields, led to discoveries of important information regarding the prenatal events that were strongly associated with mortality (or death) and morbidity (or incidences of injury, pathology and abnormalities/anomalies, and neurobehavioral sequelae) in the neonatal and infancy periods. Among the many common findings from early research studies, two are particularly noteworthy. First, maternal and fetal risk conditions arising in the prenatal period do not do so in isolation. Sameroff and Chandler characterized this …
Sex Differences In White Matter Development During Adolescence: A Dti Study, Yingying Wang, Chris Adamson, Weihong Yuan, Mekibib Altaye, Anna W. Byars, Scott K. Holland
Sex Differences In White Matter Development During Adolescence: A Dti Study, Yingying Wang, Chris Adamson, Weihong Yuan, Mekibib Altaye, Anna W. Byars, Scott K. Holland
Center for Brain, Biology, and Behavior: Faculty and Staff Publications
Adolescence is a complex transitional period in human development, composing physical maturation, cognitive and social behavioral changes. The objective of this study is to investigate sex differences in white matter development and the associations between intelligence and white matter microstructure in the adolescent brain using diffusion tensor imaging (DTI) and tract-based spatial statistics (TBSS). In a cohort of 16 typically-developing adolescents aged 13 to 17 years, longitudinal DTI data were recorded from each subject at two time points that were one year apart. We used TBSS to analyze the diffusion indices including fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity …
Do Interactions Between Motor And Visual Codes Facilitate Visuospatial Memory?: The Influence Of Action On Memory Performance: When Does It Help You, When Does It Hurt You, Michael Dodd
DBER Speaker Series
One of the hallmarks of human cognition is that we have a limited number of cognitive resources available and successful performance in the environment requires an appropriate number of these resources to be directed towards one's primary task. As such, it is unsurprising that when attention is divided between two tasks simultaneously, performance on each task suffers relative to if each task was done in isolation. At the same time, however, it has also been shown that when individuals process information in multiple ways (e.g. across more than one modality) that performance is enhanced. In the present talk I will …
Combined Erp/Fmri Evidence For Early Word Recognition Effects In The Posterior Inferior Temporal Gyrus, Joseph Dien, Eric S. Brian, Dennis L. Molfese, Brian T. Gold
Combined Erp/Fmri Evidence For Early Word Recognition Effects In The Posterior Inferior Temporal Gyrus, Joseph Dien, Eric S. Brian, Dennis L. Molfese, Brian T. Gold
Center for Brain, Biology, and Behavior: Faculty and Staff Publications
Two brain regions with established roles in reading are the posterior middle temporal gyrus and the posterior fusiform gyrus. Lesion studies have also suggested that the region located between them, the posterior inferior temporal gyrus (pITG), plays a central role in word recognition. However, these lesion results could reflect disconnection effects since neuroimaging studies have not reported consistent lexicality effects in pITG. Here we tested whether these reported pITG lesion effects are due to disconnection effects or not using parallel ERP/fMRI studies. We predicted that the Recognition Potential (RP), a left-lateralized ERP negativity that peaks at about 200–250 ms, might …
Concordance Of Meg And Fmri Patterns In Adolescents During Verb Generation, Yingying Wang, Scott K. Holland, Jennifer Vannest
Concordance Of Meg And Fmri Patterns In Adolescents During Verb Generation, Yingying Wang, Scott K. Holland, Jennifer Vannest
Center for Brain, Biology, and Behavior: Faculty and Staff Publications
In this study we focused on direct comparison between the spatial distributions of activation detected by functional magnetic resonance imaging (fMRI) and localization of sources detected by magnetoencephalography (MEG) during identical language tasks. We examined the spatial concordance between MEG and fMRI results in 16 adolescents performing a three-phase verb generation task that involves repeating the auditorily presented concrete noun and generating verbs either overtly or covertly in response to the auditorily presented noun. MEG analysis was completed using a synthetic aperture magnetometry (SAM) technique, while the fMRI data were analyzed using the general linear model approach with random-effects. To …
Is Brain-Derived Neurotrophic Factor A Possible Mechanism Underlying Risperidone Sensitization In Adolescent Rats?, Qing Shu, Gang Hu, Ming Li
Is Brain-Derived Neurotrophic Factor A Possible Mechanism Underlying Risperidone Sensitization In Adolescent Rats?, Qing Shu, Gang Hu, Ming Li
Department of Psychology: Faculty Publications
Risperidone is one of the most widely used atypical antipsychotic drugs and is approved for the treatment of mental disorders (eg. schizophrenia, autism) in children and adolescents. The present study investigated the repeated treatment effect of risperidone and associated neurotropic mechanism in the phencyclidine (PCP)-induced hyperlocomotion model in adolescent rats. We examined whether repeated risperidone treatment would cause a sensitized inhibition of PCP-induced hyperlocomotion in adolescent rats, and whether such a sensitization effect was mediated by risperidone-induced alterations in Brain-Derived Neurotrophic Factor (BDNF), an important biomarker which plays a role in neuropathology of schizophrenia and action of antipsychotic medications. Male …
A One-Hour Sleep Restriction Impacts Brain Processing In Young Children Across Tasks: Evidence From Event-Related Potentials, Dennis Molfese, Anna Ivanenko, Alexandra P.F. Key, Adrienne Roman, Victoria J. Molfese, Louise M. O'Brien, David Gozal, Srinivas Kota, Caitlin M. Hudac
A One-Hour Sleep Restriction Impacts Brain Processing In Young Children Across Tasks: Evidence From Event-Related Potentials, Dennis Molfese, Anna Ivanenko, Alexandra P.F. Key, Adrienne Roman, Victoria J. Molfese, Louise M. O'Brien, David Gozal, Srinivas Kota, Caitlin M. Hudac
Center for Brain, Biology, and Behavior: Faculty and Staff Publications
The effect of mild sleep restriction on cognitive functioning in young children is unclear, yet sleep loss may impact children's abilities to attend to tasks with high processing demands. In a preliminary investigation, six children (6.6 - 8.3 years of age) with normal sleep patterns performed three tasks: attention (“Oddball”), speech perception (conconant-vowel syllables) and executive function (Directional Stroop). Event-related potentials (ERP) responses were recorded before (Control) and following one-week of 1-hour per day of sleep restriction. Brain activity across all tasks following Sleep Restriction differed from activity during Control Sleep, indicating that minor sleep restriction impacts children's neurocognitive functioning.
Normative Topographic Erp Analyses Of Speed Of Speech Processing And Grammar Before And After Grammatical Treatment, Paul J. Yoder, Dennis Molfese, Micah M. Murray, Alexandra P.F. Key
Normative Topographic Erp Analyses Of Speed Of Speech Processing And Grammar Before And After Grammatical Treatment, Paul J. Yoder, Dennis Molfese, Micah M. Murray, Alexandra P.F. Key
Center for Brain, Biology, and Behavior: Faculty and Staff Publications
Typically developing (TD) preschoolers and age-matched preschoolers with specific language impairment (SLI) received event-related potentials (ERPs) to four monosyllabic speech sounds prior to treatment and, in the SLI group, after 6 months of grammatical treatment. Before treatment, the TD group processed speech sounds faster than the SLI group. The SLI group increased the speed of their speech processing after treatment. Post-treatment speed of speech processing predicted later impairment in comprehending phrase elaboration in the SLI group. During the treatment phase, change in speed of speech processing predicted growth rate of grammar in the SLI group.