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Full-Text Articles in Medicine and Health Sciences

Evaluating The Bioavailability Of Carbamazepine Using A Novel Snedds Formulation, Jinwon Byun, Derrick L. Chapman, Rebecca A. Kyper, Gina M. Mattes, Zachary A. Wallace, Elisha R. Injeti Dec 2013

Evaluating The Bioavailability Of Carbamazepine Using A Novel Snedds Formulation, Jinwon Byun, Derrick L. Chapman, Rebecca A. Kyper, Gina M. Mattes, Zachary A. Wallace, Elisha R. Injeti

Pharmacy and Nursing Student Research and Evidence-Based Medicine Poster Session

Central to the mechanism of how drugs work are the concepts of solubility and bioavailability. Drugs enter the body via absorption into the bloodstream, arrive at the target location, and bind to receptors to cause an effect. Drugs need to be soluble enough to pass through the cell membrane to enter and exit the bloodstream. Higher solubility generally correlates to higher bioavailability. Additionally, the smaller the particle size, the easier the drug will pass through the membrane into the blood plasma. Researchers have designed a system to categorize solubility class: Class I being high permeability and high solubility, Class II …


Effectiveness Of Clinical Scenarios In Improving Student Interprofessional Skills And Attitudes, Ashley Peterson, Mike Pelyhes, Laura Cummings, Phillip L. Thornton, Zachary N. Jenkins Dec 2013

Effectiveness Of Clinical Scenarios In Improving Student Interprofessional Skills And Attitudes, Ashley Peterson, Mike Pelyhes, Laura Cummings, Phillip L. Thornton, Zachary N. Jenkins

Pharmacy and Nursing Student Research and Evidence-Based Medicine Poster Session

Background: “Interprofessional education (IPE) is defined as the process by which individuals from two or more health professions learn with, from, and about each other across the spectrum of their education to improve collaboration, practice, and the quality of health care.” [1] Interprofessional Education has recently gained interest as an important aspect of training in healthcare professions, attracting the attention and support of several key pharmacy organizations. Various models of IPE have been implemented to facilitate collaboration among medical, nursing, pharmacy, and social work students and professionals. One model found to be particularly effective among pharmacy students is a mock …


Natural Products As Therapeutic Agents In Cancer Treatment, Eric Huseman, Lauren P. Williams, Brittany Santee, Trevor Stump, Chelsae Ward, Rachel Kunze, Denise S. Simpson, Samson Amos Dec 2013

Natural Products As Therapeutic Agents In Cancer Treatment, Eric Huseman, Lauren P. Williams, Brittany Santee, Trevor Stump, Chelsae Ward, Rachel Kunze, Denise S. Simpson, Samson Amos

Pharmacy and Nursing Student Research and Evidence-Based Medicine Poster Session

Cancer accounts for 25% of deaths in the United States, and brain tumors greatly contribute to this percentage. However, relative to other types of cancers, brain tumors prove difficult to treat because they are heterogeneous, highly proliferative, highly invasive, and resistant to the traditional cancer treatments of chemotherapy and radiotherapy. Past studies have shown that flavonoids and curcuminoids, two classes of compounds derived from natural sources, are effective in inhibiting the development and metastasis of breast and lung cancer cells. Research has also indicated that these compounds have potential for treating brain tumors.

The purpose of this research is to …


The Pivotal Role Of The Pharmacist In A Primary Care Office, Julie Cummings, Olumami O. Amaye, Mckenzie Shenk, Cara Toms, Nathanael Smith, Thaddeus T. Franz, Tracy R. Frame Dec 2013

The Pivotal Role Of The Pharmacist In A Primary Care Office, Julie Cummings, Olumami O. Amaye, Mckenzie Shenk, Cara Toms, Nathanael Smith, Thaddeus T. Franz, Tracy R. Frame

Pharmacy and Nursing Student Research and Evidence-Based Medicine Poster Session

Abstract

The profession of pharmacy has evolved from a dispensing role to an interdisciplinary clinical role in patient care. One area of patient care expertise is Medication Therapy Management (MTM), which includes services such as pharmacotherapy, medication therapy reviews, disease management, immunizations and other clinical services. In various studies, pharmacists conducting MTM have shown improved patient outcomes in community pharmacy and hospital settings. Amidst the valuable services all healthcare professionals are providing, increasing medical costs and consequences have become overwhelming, leading to negative patient outcomes. A lack of primary care physicians (PCPs) may contribute to these distressing facts. Gaps in …


Efficacy Of Marketing Strategy For Reach Vitamins, Jessica Davis, Jordan Long, Megan Buck, Paul Bicknell, Melody L. Hartzler Dec 2013

Efficacy Of Marketing Strategy For Reach Vitamins, Jessica Davis, Jordan Long, Megan Buck, Paul Bicknell, Melody L. Hartzler

Pharmacy and Nursing Student Research and Evidence-Based Medicine Poster Session

According to the 2009 Global Report, Vitamin A supplementation in children reduces the death rate by 23% in populations at risk of deficiency. REACH Vitamins is a for-profit business that provides a one-year supply of vitamin A to children in underprivileged countries for each bottle of vitamins A, B, C, D, or the multivitamin purchased. The primary objective of this exploratory, qualitative study is to determine if there is a more appropriate marketing strategy for REACH Vitamins compared to the current marketing strategy used. The secondary objective is to determine if REACH Vitamins’ charity motivates consumers to purchase their products. …


Development Of A Novel Aspirin Suppository Formulation And Evaluation Of The Acetylation Of Cox-1 Via A Ht-29/Caco-2 Cell Absorption Assay Used To Detect The Absorption Of Aspirin Formulated With Various Bases And Excipients, Tiffany J. Zehel, Danielle L. Eaton, Sarah A. Myers, Mallory J. Martin, Joseph D. Newman, Rocco J. Rotello, Miriam A. Ansong Jan 2013

Development Of A Novel Aspirin Suppository Formulation And Evaluation Of The Acetylation Of Cox-1 Via A Ht-29/Caco-2 Cell Absorption Assay Used To Detect The Absorption Of Aspirin Formulated With Various Bases And Excipients, Tiffany J. Zehel, Danielle L. Eaton, Sarah A. Myers, Mallory J. Martin, Joseph D. Newman, Rocco J. Rotello, Miriam A. Ansong

Pharmacy and Nursing Student Research and Evidence-Based Medicine Poster Session

As the baby-boomer population ages, hospitalization rates will rise, increasing the number of patients who are NPO. Research indicates that aspirin use also increases with advanced age. With the increased prevalence of this demographic, there continues to be a growing need for alternative dosage forms for aspirin administration. A common and limited-risk alternative is rectally administered aspirin. However, there appears to be only one commercially available aspirin suppository and it has yielded erratic results as shown in previous research.

Aspirin is considered a pro-drug; once it is inside the body, the acidic environment cleaves the aspirin molecule down to salicylic …