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Full-Text Articles in Medicine and Health Sciences

Pegylated Interferon 2a And 2b In Combination With Ribavirin For The Treatment Of Chronic Hepatitis C In Hiv Infected Patients., Ravinder Dhillon, Simona Rossi, Steven K Herrine Aug 2008

Pegylated Interferon 2a And 2b In Combination With Ribavirin For The Treatment Of Chronic Hepatitis C In Hiv Infected Patients., Ravinder Dhillon, Simona Rossi, Steven K Herrine

Department of Medicine Faculty Papers

Coinfection with hepatitis C virus (HCV) and HIV is an increasingly recognized clinical dilemma, particularly since the advent of highly active antiretroviral therapy. Several studies of this population have demonstrated both more rapid progression of liver disease and poorer overall prognosis compared to HCV monoinfected patients. Consensus guidelines, based primarily on the results of 4 major randomized trials, recommend treatment with peginterferon and ribavirin for 48 weeks in coinfected patients. However, this current standard of care is associated with lower response rates to therapy than those seen in monoinfected patients. Important predictors of response include HCV genotype, pretreatment HCV RNA …


Effect Of Short-Term Failure Versus Nonfailure Training On Lower Body Muscular Endurance, Jeffrey Willardson, John Emmett, Jon A. Oliver, Eadric Bressel Jan 2008

Effect Of Short-Term Failure Versus Nonfailure Training On Lower Body Muscular Endurance, Jeffrey Willardson, John Emmett, Jon A. Oliver, Eadric Bressel

Faculty Research and Creative Activity

This study compared failure versus nonfailure training with equated intensity and volume on lower body muscular endurance in trained men. Methods: Each subject performed one lower body workout per week for 6 weeks; the Failure group performed 3 sets of the squat, leg curl, and leg extension exercises to the point of voluntary exhaustion, while the Nonfailure group performed 4 sets for each of these exercises, but with a submaximal number of repetitions that did not allow failure to occur on any set. All subjects performed a pre- and postintervention muscular endurance test that involved 3 sets each for the …