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Full-Text Articles in Medicine and Health Sciences

Bayesian Regularization To Predict Neuropsychiatric Adverse Events In Smoking Cessation With Pharmacotherapy, Van Thi Thanh Truong, Charles Green, Claudia Pedroza, Lu-Yu Hwang, Suja S Rajan, Robert Suchting, Paul Cinciripini, Rachel F Tyndale, Caryn Lerman Apr 2023

Bayesian Regularization To Predict Neuropsychiatric Adverse Events In Smoking Cessation With Pharmacotherapy, Van Thi Thanh Truong, Charles Green, Claudia Pedroza, Lu-Yu Hwang, Suja S Rajan, Robert Suchting, Paul Cinciripini, Rachel F Tyndale, Caryn Lerman

Journal Articles

BACKGROUND: Research on risk factors for neuropsychiatric adverse events (NAEs) in smoking cessation with pharmacotherapy is scarce. We aimed to identify predictors and develop a prediction model for risk of NAEs in smoking cessation with medications using Bayesian regularization.

METHODS: Bayesian regularization was implemented by applying two shrinkage priors, Horseshoe and Laplace, to generalized linear mixed models on data from 1203 patients treated with nicotine patch, varenicline or placebo. Two predictor models were considered to separate summary scores and item scores in the psychosocial instruments. The summary score model had 19 predictors or 26 dummy variables and the item score …


Worse Postoperative Outcomes And Higher Reoperation In Smokers Compared To Nonsmokers For Arthroscopic Rotator Cuff Repair, Susan G. Wager, Spencer Brown, Michael Gaudiani, Joshua P. Castle, Eric Jiang, Vasilios Moutzouros, Eric Makhni, Stephanie J. Muh Mar 2023

Worse Postoperative Outcomes And Higher Reoperation In Smokers Compared To Nonsmokers For Arthroscopic Rotator Cuff Repair, Susan G. Wager, Spencer Brown, Michael Gaudiani, Joshua P. Castle, Eric Jiang, Vasilios Moutzouros, Eric Makhni, Stephanie J. Muh

Medical Student Research Symposium

Introduction: Smoking impairs healing potential and is a significant risk factor for complications following orthopaedic surgeries. The purpose of this study was to determine if a cohort of former or current smokers at time of surgery met the minimally clinical important difference (MCID) for Patient-Reported Outcomes Measurement Information System Upper Extremity (PROMIS-UE), Depression (PROMIS-D), and Pain Interference (PROMIS-PI) scores in comparison to nonsmokers.

Methods: A retrospective review of patients who underwent rotator cuff repair was performed. Patients who completed preoperative and 6-month postoperative PROMIS scores were included. The MCID was calculated using a distribution technique with a threshold of 0.5 …


State Variation In Squamous Cell Carcinoma Of The Anus Incidence And Mortality, And Association With Hiv/Aids And Smoking In The United States, Haluk Damgacioglu, Yueh-Yun Lin, Ana Patricia Ortiz, Chi-Fang Wu, Zahed Shahmoradi, Shiang Shiuan Shyu, Ruosha Li, Alan G Nyitray, Keith Sigel, Gary M Clifford, Naomi Jay, Vivian Colon Lopez, Gregory M Barnell, Elizabeth Y Chiao, Elizabeth A Stier, Karen J Ortiz-Ortiz, Jeslie M Ramos-Cartagena, Kalyani Sonawane, Ashish A Deshmukh Feb 2023

State Variation In Squamous Cell Carcinoma Of The Anus Incidence And Mortality, And Association With Hiv/Aids And Smoking In The United States, Haluk Damgacioglu, Yueh-Yun Lin, Ana Patricia Ortiz, Chi-Fang Wu, Zahed Shahmoradi, Shiang Shiuan Shyu, Ruosha Li, Alan G Nyitray, Keith Sigel, Gary M Clifford, Naomi Jay, Vivian Colon Lopez, Gregory M Barnell, Elizabeth Y Chiao, Elizabeth A Stier, Karen J Ortiz-Ortiz, Jeslie M Ramos-Cartagena, Kalyani Sonawane, Ashish A Deshmukh

Journal Articles

PURPOSE: Squamous cell carcinoma of the anus (SCCA) incidence and mortality rates are rising in the United States. Understanding state-level incidence and mortality patterns and associations with smoking and AIDS prevalence (key risk factors) could help unravel disparities and provide etiologic clues.

METHODS: Using the US Cancer Statistics and the National Center for Health Statistics data sets, we estimated state-level SCCA incidence and mortality rates. Rate ratios (RRs) were calculated to compare incidence and mortality in 2014-2018 versus 2001-2005. The correlations between SCCA incidence with current smoking (from the Behavioral Risk Factor Surveillance System) and AIDS (from the HIV Surveillance …


Serum Cotinine As A Predictor Of Lipid-Related Indices In Turkish Immigrants With Type 2 Diabetes: A Clinic-Based Cross-Sectional Study, Shiryn D. Sukhram, Gustavo G. Zarini, Lemia H. Shaban, Joan A. Vaccaro, Avinash R. Sukhram, Fatma G. Huffman Feb 2023

Serum Cotinine As A Predictor Of Lipid-Related Indices In Turkish Immigrants With Type 2 Diabetes: A Clinic-Based Cross-Sectional Study, Shiryn D. Sukhram, Gustavo G. Zarini, Lemia H. Shaban, Joan A. Vaccaro, Avinash R. Sukhram, Fatma G. Huffman

Publications and Research

Background: Turkish immigrants form the largest ethnic minority group in the

Netherlands and show a higher prevalence of (i) cardiovascular disease (CVD),

(ii) cigarette smoking, and (iii) type 2 diabetes (T2D) as compared to the native

Dutch. This study examines the association of CVD risk factors: serum cotinine, as

an indicator of cigarette smoke, and lipid-related indices among first-generation

(foreign-born) Turkish immigrants with T2D living in deprived neighbourhoods in the

Netherlands.

Methods: A total of 110 participants, physician-diagnosed with T2D, aged 30 years

and older, were recruited by convenience sampling from the Schilderswijk

neighbourhood of The Hague in a clinic-based …


Smoking Cessation Through Optimisation Of Clinical Care In Pregnancy: The Stop Randomised Controlled Trial, Brendan P. Mcdonnell, Patrick Dicker, Sheila Keogan, Luke Clancy, Carmen Regan Jan 2023

Smoking Cessation Through Optimisation Of Clinical Care In Pregnancy: The Stop Randomised Controlled Trial, Brendan P. Mcdonnell, Patrick Dicker, Sheila Keogan, Luke Clancy, Carmen Regan

Articles

This is a pragmatic randomised controlled trial of a dedicated smoking cessation clinic versus routine antenatal care as an intervention to reduce cigarette smoking behaviour. Smoking mothers randomised to the Smoking cessation Through Optimisation of clinical care in Pregnancy (STOP) clinic will have all antenatal care provided by a team comprising an obstetrician, a midwife, and a smoking cessation practitioner. This intervention includes ultrasound screening for fetal growth restriction. The control arm comprises two groups: one receiving standard care with ultrasound screening for fetal growth restriction, and one receiving standard care with ultrasound screening for growth restriction only if clinically …


The Role Of Smoking In Covid-19 Progression: A Comprehensive Meta-Analysis, Silvano Gallus, Marco Scala, Irene Possenti, Carlotta Micaela Jarach, Luke Clancy, Esteve Fernandez, Giuseppe Gorini, Giulia Carreras, Maria Chiara Malevolti, Alison Commar, Ranti Fayokun, Hebe N. Gouda, Vinayak M. Prasad, Alessandra Lugo Jan 2023

The Role Of Smoking In Covid-19 Progression: A Comprehensive Meta-Analysis, Silvano Gallus, Marco Scala, Irene Possenti, Carlotta Micaela Jarach, Luke Clancy, Esteve Fernandez, Giuseppe Gorini, Giulia Carreras, Maria Chiara Malevolti, Alison Commar, Ranti Fayokun, Hebe N. Gouda, Vinayak M. Prasad, Alessandra Lugo

Articles

The association between current smoking and coronavirus disease 2019 (COVID-19) progression remains uncertain. We aim to provide up-to-date evidence of the role of cigarette smoking in COVID-19 hospitalisation, severity and mortality. On 23 February 2022 we conducted an umbrella review and a traditional systematic review via PubMed/Medline and Web of Science. We used random-effects meta-analyses to derive pooled odds ratios of COVID-19 outcomes for smokers in cohorts of severe acute respiratory syndrome coronavirus 2 infected individuals or COVID-19 patients. We followed the Meta-analysis of Observational Studies in Epidemiology reporting guidelines. PROSPERO: CRD42020207003. 320 publications were included. The pooled odds ratio …


The Relationship Between Diet And Lifestyle Behaviours In A Sample Of Higher Education Students; A Cross-Sectional Study, Stephen Doak, John Kearney, Jacqueline M. Mccormack, Laura Keaver Jan 2023

The Relationship Between Diet And Lifestyle Behaviours In A Sample Of Higher Education Students; A Cross-Sectional Study, Stephen Doak, John Kearney, Jacqueline M. Mccormack, Laura Keaver

Articles

Transitioning into higher education (HE) impacts health behaviours. Poor dietary and lifestyle behaviours may correlate and increase risk of co-morbidities. The introduction of the Okanagan Charter detailed the important role of health promotion within a HE setting. The aim of this study was to assess the relationship between dietary quality and lifestyle behaviours of students attending HE.


Biomarkers Of Toxic Exposure And Oxidative Stress Among U.S. Adult Users Of Premium Cigar Versus Other Cigar Subtypes: 2013-2019, Hongying Dai, Neal L. Benowitz, Eleanor Rogan, Abraham Degarege, James Buckley, Ali S. Khan Jan 2023

Biomarkers Of Toxic Exposure And Oxidative Stress Among U.S. Adult Users Of Premium Cigar Versus Other Cigar Subtypes: 2013-2019, Hongying Dai, Neal L. Benowitz, Eleanor Rogan, Abraham Degarege, James Buckley, Ali S. Khan

Journal Articles: Epidemiology

INTRODUCTION: Cigars are currently the second-highest-used combustible tobacco product among U.S. adults, but knowledge about health effects of premium cigars versus other cigar subtype use is limited.

AIMS AND METHODS: This study analyzed the biospecimen data (n = 31 875) from Waves 1-5 of the Population Assessment of Tobacco and Health Study, collected during 2013-2019. Multivariable generalized estimation equations, accounting for within-person clustering, were conducted to examine differences in urine biomarkers of exposure (BOE) from five classes of harmful and potentially harmful constituents along with a biomarker of oxidative stress (urine 8-isoprostane) among exclusive users of premium cigars versus other …


The Clusters Of Health-Risk Behaviours And Mental Wellbeing And Their Sociodemographic Correlates: A Study Of 15,366 Asean University Students, Apichai Wattanapisit, Hanif Abdul Raman, Josip Car, Khadizah H. Abdul-Mumin, Ma. Henrietta Teresa O. De La Cruz, Michael Chia, Michael Rosenberg, Moon-Ho Ringo Ho, Surasak Chaiyasong, Trias Mahmudiono Oct 2022

The Clusters Of Health-Risk Behaviours And Mental Wellbeing And Their Sociodemographic Correlates: A Study Of 15,366 Asean University Students, Apichai Wattanapisit, Hanif Abdul Raman, Josip Car, Khadizah H. Abdul-Mumin, Ma. Henrietta Teresa O. De La Cruz, Michael Chia, Michael Rosenberg, Moon-Ho Ringo Ho, Surasak Chaiyasong, Trias Mahmudiono

Ateneo School of Medicine and Public Health Publications

Background

This study investigated, through cluster analysis, the associations between behavioural characteristics, mental wellbeing, demographic characteristics, and health among university students in the Association of Southeast Asian Nations (ASEAN) University Network – Health Promotion Network (AUN-HPN) member universities.

Methods

Data were retrieved from a cross-sectional self-administered online survey among undergraduate students in seven ASEAN countries. A two-step cluster analysis was employed, with cluster labels based on the predominant characteristics identified within the clusters. The ‘healthy’ cluster was assigned as the reference group for comparisons using multinomial logistic regression analysis.

Results

The analytic sample size comprised 15,366 university students. Five clusters …


Prevalence Of Health-Risk Behaviors And Mental Well-Being Of Asean University Students In Covid-19 Pandemic, Hanif Abdul Raman, Areekul Amornsriwatanakul, Khadizah H. Abdul-Mumin, Denny Agustiningsih, Surasak Chaiyasong, Michael Chia, Supat Chupradit, Le Quang Huy, Katiya Ivanovitch, Ma. Henrietta Teresa O. De La Cruz Jul 2022

Prevalence Of Health-Risk Behaviors And Mental Well-Being Of Asean University Students In Covid-19 Pandemic, Hanif Abdul Raman, Areekul Amornsriwatanakul, Khadizah H. Abdul-Mumin, Denny Agustiningsih, Surasak Chaiyasong, Michael Chia, Supat Chupradit, Le Quang Huy, Katiya Ivanovitch, Ma. Henrietta Teresa O. De La Cruz

Ateneo School of Medicine and Public Health Publications

The prevalence of epidemiological health-risk behaviors and mental well-being in the COVID-19 pandemic, stratified by sociodemographic factors in Association of South East Asian Nations (ASEAN) university students, were examined in the research. Data were collected in March–June 2021 via an online survey from 15,366 university students from 17 universities in seven ASEAN countries. Analyzed data comprised results on physical activity, health-related behaviors, mental well-being, and sociodemographic information. A large proportion of university students consumed sugar-sweetened beverages (82.0%; 95%CI: 81.4, 82.6) and snacks/fast food daily (65.2%; 95%CI: 64.4, 66.0). About half (52.2%; 95%CI: 51.4, 53.0) consumed less than the recommended daily …


Validation Of A High Flow Rate Puff Topography System Designed For Measurement Of Sub-Ohm, Third Generation Electronic Nicotine Delivery Systems, Evan Floyd, Toluwanimi Oni, Changjie Cai, Bilal Rehman, Jooyeon Hwang, Tyler Watson Jun 2022

Validation Of A High Flow Rate Puff Topography System Designed For Measurement Of Sub-Ohm, Third Generation Electronic Nicotine Delivery Systems, Evan Floyd, Toluwanimi Oni, Changjie Cai, Bilal Rehman, Jooyeon Hwang, Tyler Watson

Journal Articles

There are few known puff topography devices designed solely for gathering electronic cigarette puff topography information, and none made for high-powered sub-ohm devices. Ten replicate Bernoulli flow cells were designed and 3D printed. The relationship between square root of pressure difference and flow rate was determined across 0−70 L/min. One representative flow cell was used to estimate puff volume and flow rate under six simulated puffing regimes (0.710 L, 2.000 L and 3.000 L, at low and high flow rates) to determine the system’s accuracy and utility of using dual pressure sensors for flow measurement. The relationship between flow rate …


Consumption, Nicotine Dependence And Motivation For Smoke Cessation During Early Stages Of Covid-19 Pandemic In Brazil: A Cross-Sectional Study, Ana Paula Coelho Figueira Freire, Bruna A.S. Medina, Marceli R. Leite, Tainá O. Lopes, Ester T. Santos, Milena M. Ferreira, Bruna S.A. Silva, Margaret A. Cavalcante, Francis L. Pacagnelli May 2022

Consumption, Nicotine Dependence And Motivation For Smoke Cessation During Early Stages Of Covid-19 Pandemic In Brazil: A Cross-Sectional Study, Ana Paula Coelho Figueira Freire, Bruna A.S. Medina, Marceli R. Leite, Tainá O. Lopes, Ester T. Santos, Milena M. Ferreira, Bruna S.A. Silva, Margaret A. Cavalcante, Francis L. Pacagnelli

All Faculty Scholarship for the College of Education and Professional Studies

Introduction: The COVID-19 pandemic may have changed smoking habits. For the smoking population, information regarding smoking habits and the pandemic could potentially aid COVID-19 prevention and control measures. Our study aimed to analyze the effects of the COVID-19 pandemic on tobacco consumption, nicotine dependence levels, and motivation for smoking cessation. We also collected information from smokers regarding their awareness of the consequences of tobacco use and the increased risks smokers have for severe complications from COVID-19.

Methods: In the survey for this observational cross-sectional study, 122 smokers responded to an online form. The participants provided general data about their smoking …


Sociodemographic, Personal, Peer, And Familial Predictors Of E-Cigarette Ever Use In Espad Ireland: A Forward Stepwise Logistic Regression Model, Joan Hanafin, Salome Sunday, Luke Clancy Feb 2022

Sociodemographic, Personal, Peer, And Familial Predictors Of E-Cigarette Ever Use In Espad Ireland: A Forward Stepwise Logistic Regression Model, Joan Hanafin, Salome Sunday, Luke Clancy

Articles

Introduction:
E-cigarette ever use has risen significantly in recent years in Ireland, similar to trends elsewhere in Europe, the United States, and Asia-Pacific region. Results from ESPAD Ireland (European School Survey Project on Alcohol and other Drugs) show teenage e-cigarette ever use increased from 18% (2015) to 37% (2019). Given this increase, our aim is to profile e-cigarette ever users and never users in this age group; to examine sociodemographic, personal, peer, and familial factors associated with e-cigarette ever use; and to suggest appropriate measures to reduce use.

Methods:
A nationally representative stratified random sample of 50 ESPAD schools was …


The Impact Of Covid-19 On Risky Behaviors And Health Changes In African-American Smokers Who Are Eligible For Ldct Screening, Tung-Sung Tseng, Mirandy Li, Yu Hsiang Kao, Lei Shih Chen, Hui Yi Lin Dec 2021

The Impact Of Covid-19 On Risky Behaviors And Health Changes In African-American Smokers Who Are Eligible For Ldct Screening, Tung-Sung Tseng, Mirandy Li, Yu Hsiang Kao, Lei Shih Chen, Hui Yi Lin

School of Public Health Faculty Publications

The COVID-19 pandemic has disrupted much of day-to-day life in the US and around the world. Smokers have a higher risk of adverse outcomes due to COVID-19. This study investigated the impact of COVID-19 on risky behaviors and health changes in lower income African-American smokers eligible for Low dose computed tomography (LDCT) screening, who may be more adversely impacted by the COVID-19 pandemic. A total of 22 African-American daily smokers who were eligible for LDCT screening participated in this study. The mean age of participants was 61.2 years old (SD = 4.7), 77.3% of the smokers were female, all participants …


Changes Of Exercise, Screen Time, Fast Food Consumption, Alcohol, And Cigarette Smoking During The Covid-19 Pandemic Among Adults In The United States, Liwei Chen, Jian Li, Tong Xia, Timothy A. Matthews, Tung-Sung Tseng, Lu Shi, Donglan Zhang, Zhuo Chen, Xuesong Han, Yan Li, Hongmei Li, Ming Wen, Dejun Su Sep 2021

Changes Of Exercise, Screen Time, Fast Food Consumption, Alcohol, And Cigarette Smoking During The Covid-19 Pandemic Among Adults In The United States, Liwei Chen, Jian Li, Tong Xia, Timothy A. Matthews, Tung-Sung Tseng, Lu Shi, Donglan Zhang, Zhuo Chen, Xuesong Han, Yan Li, Hongmei Li, Ming Wen, Dejun Su

School of Public Health Faculty Publications

Objective: To investigate the impact of the COVID-19 pandemic on multiple lifestyle changes among adults in the United States (USA). Methods: We conducted a survey, the Health, Ethnicity, and Pandemic (HEAP) Study, in October 2020 among USA adults. Participants were selected from the United States using 48 sampling strata, including age, race, ethnicity, education, and gender, and were asked to report five lifestyle behaviors (i.e., exercise time, screen time, fast-food meal consumption, alcohol drinking, and cigarette smoking) before and during the COVID-19 pandemic. The associations of sociodemographic factors with each lifestyle change were estimated using weighted multivariable logistic regression models. …


Chronic Airflow Obstruction And Ambient Particulate Air Pollution, Andre F S. Amaral, Peter G J. Burney, Jaymini Patel, Cosetta Minelli, Filip Mejza, David M. Mannino, Terence A R. Seemungal, Padukudru Anand Mahesh, Li Cher Lo, Asaad Ahmed Nafees May 2021

Chronic Airflow Obstruction And Ambient Particulate Air Pollution, Andre F S. Amaral, Peter G J. Burney, Jaymini Patel, Cosetta Minelli, Filip Mejza, David M. Mannino, Terence A R. Seemungal, Padukudru Anand Mahesh, Li Cher Lo, Asaad Ahmed Nafees

Community Health Sciences

Smoking is the most well-established cause of chronic airflow obstruction (CAO) but particulate air pollution and poverty have also been implicated. We regressed sex-specific prevalence of CAO from 41 Burden of Obstructive Lung Disease study sites against smoking prevalence from the same study, the gross national income per capita and the local annual mean level of ambient particulate matter (PM2.5) using negative binomial regression. The prevalence of CAO was not independently associated with PM2.5 but was strongly associated with smoking and was also associated with poverty. Strengthening tobacco control and improved understanding of the link between CAO and poverty should …


Genetic And Non-Genetic Factors Affecting The Expression Of Covid-19-Relevant Genes In The Large Airway Epithelium, Silva Kasela, Victor E Ortega, Molly Martorella, Suresh Garudadri, Jenna Nguyen, Elizabeth Ampleford, Anu Pasanen, Srilaxmi Nerella, Kristina L Buschur, Igor Z Barjaktarevic, R Graham Barr, Eugene R Bleecker, Russell P Bowler, Alejandro P Comellas, Christopher B Cooper, David J Couper, Gerard J Criner, Jeffrey L Curtis, Meilan K Han, Nadia N Hansel, Eric A Hoffman, Robert J Kaner, Jerry A Krishnan, Fernando J Martinez, Merry-Lynn N Mcdonald, Deborah A Meyers, Robert Paine, Stephen P Peters, Mario Castro, Loren C Denlinger, Serpil C Erzurum, John V Fahy, Elliot Israel, Nizar N Jarjour, Bruce D Levy, Xingnan Li, Wendy C Moore, Sally E Wenzel, Charles Langelier, Prescott G Woodruff, Tuuli Lappalainen, Stephanie A Christenson Apr 2021

Genetic And Non-Genetic Factors Affecting The Expression Of Covid-19-Relevant Genes In The Large Airway Epithelium, Silva Kasela, Victor E Ortega, Molly Martorella, Suresh Garudadri, Jenna Nguyen, Elizabeth Ampleford, Anu Pasanen, Srilaxmi Nerella, Kristina L Buschur, Igor Z Barjaktarevic, R Graham Barr, Eugene R Bleecker, Russell P Bowler, Alejandro P Comellas, Christopher B Cooper, David J Couper, Gerard J Criner, Jeffrey L Curtis, Meilan K Han, Nadia N Hansel, Eric A Hoffman, Robert J Kaner, Jerry A Krishnan, Fernando J Martinez, Merry-Lynn N Mcdonald, Deborah A Meyers, Robert Paine, Stephen P Peters, Mario Castro, Loren C Denlinger, Serpil C Erzurum, John V Fahy, Elliot Israel, Nizar N Jarjour, Bruce D Levy, Xingnan Li, Wendy C Moore, Sally E Wenzel, Charles Langelier, Prescott G Woodruff, Tuuli Lappalainen, Stephanie A Christenson

Journal Articles

BACKGROUND: The large airway epithelial barrier provides one of the first lines of defense against respiratory viruses, including SARS-CoV-2 that causes COVID-19. Substantial inter-individual variability in individual disease courses is hypothesized to be partially mediated by the differential regulation of the genes that interact with the SARS-CoV-2 virus or are involved in the subsequent host response. Here, we comprehensively investigated non-genetic and genetic factors influencing COVID-19-relevant bronchial epithelial gene expression.

METHODS: We analyzed RNA-sequencing data from bronchial epithelial brushings obtained from uninfected individuals. We related ACE2 gene expression to host and environmental factors in the SPIROMICS cohort of smokers with …


Persistent Disparities In Smoking Among Rural Appalachians: Evidence From The Mountain Air Project, Kathryn Cardarelli, Susan C. Westneat, Madeline Dunfee, Beverly May, Nancy Schoenberg, Steven R. Browning Feb 2021

Persistent Disparities In Smoking Among Rural Appalachians: Evidence From The Mountain Air Project, Kathryn Cardarelli, Susan C. Westneat, Madeline Dunfee, Beverly May, Nancy Schoenberg, Steven R. Browning

Health, Behavior & Society Faculty Publications

BACKGROUND: Adult smoking prevalence in Central Appalachia is the highest in the United States, yet few epidemiologic studies describe the smoking behaviors of this population. Using a community-based approach, the Mountain Air Project (MAP) recruited the largest adult cohort from Central Appalachia, allowing us to examine prevalence and patterns of smoking behavior.

METHODS: A cross-sectional epidemiologic study of 972 participants aged 21 years and older was undertaken 2015-2017, with a response rate of 82%. Prevalence ratios and 95% confidence intervals for current smoking (compared to nonsmokers) were computed for the entire cohort then stratified by multiple characteristics, including respiratory health. …


Smart Homes For Smart Health: Developing An Interactive System To Reduce In-Home Secondhand Smoke, Christie Kika, Janice Han, Vincent Berardi Dec 2020

Smart Homes For Smart Health: Developing An Interactive System To Reduce In-Home Secondhand Smoke, Christie Kika, Janice Han, Vincent Berardi

Student Scholar Symposium Abstracts and Posters

Smoke from any source is potentially harmful because it contains fine particulate matter that is associated with acute and chronic conditions. Second-hand smoke (SHS) is particularly unsafe for children due to biological characteristics (higher breathing rates, immature lungs and underdeveloped immune systems) that make it difficult to filter toxins.To address this concern, we recently completed Project Fresh Air (PFA), an NIH-funded R01 intervention that installed air particle sensors in the households of tobacco smokers who lived with children. The purpose of our research is to investigate and develop efficient smart home devices that monitor SHS in various living spaces to …


The Intersection Of An Epidemic And Pandemic: Smoking, Risk-Taking, And Covid-19, Allison H. Stranick Oct 2020

The Intersection Of An Epidemic And Pandemic: Smoking, Risk-Taking, And Covid-19, Allison H. Stranick

Student Publications

Electronic cigarette use has risen drastically in recent years among teens and young adults. Rates of conventional cigarette use have decreased, while rates of electronic cigarette use are on the rise. Knowledge and perceptions of the risks and benefits of conventional and electronic cigarettes greatly impacts adolescents and young adults’ decisions to use these products. Published literature explores the issues of social norms, intertemporal choice, present bias, prospect theory, and hyperbolic discounting as means to explain the way in which young populations perceive risk and risky behavior. Research suggests that children and young adults believe that e-cigarettes are safer, less …


Encoding The Odor Of Cigarette Smoke, Timothy S. Mcclintock, Naazneen Khan, Yelena Alimova, Madeline Aulisio, Dong Y. Han, Patrick Breheny Sep 2020

Encoding The Odor Of Cigarette Smoke, Timothy S. Mcclintock, Naazneen Khan, Yelena Alimova, Madeline Aulisio, Dong Y. Han, Patrick Breheny

Physiology Faculty Publications

The encoding of odors is believed to begin as a combinatorial code consisting of distinct patterns of responses from odorant receptors (ORs), trace-amine associated receptors (TAARs), or both. To determine how specific response patterns arise requires detecting patterns in vivo and understanding how the components of an odor, which are nearly always mixtures of odorants, give rise to parts of the pattern. Cigarette smoke, a common and clinically relevant odor consisting of > 400 odorants, evokes responses from 144 ORs and 3 TAARs in freely behaving male and female mice, the first example of in vivo responses of both ORs and …


Feasibility And Acceptability Of A Culturally- And Linguistically-Adapted Smoking Cessation Text Messaging Intervention For Latino Smokers., Francisco Cartujano-Barrera, Lisa Sanderson Cox, Evelyn Arana-Chicas, Mariana Ramírez, Jaime Perales-Puchalt, Pamela Valera, Francisco J. Díaz, Delwyn Catley, Edward F. Ellerbeck, Ana Paula Cupertino Jun 2020

Feasibility And Acceptability Of A Culturally- And Linguistically-Adapted Smoking Cessation Text Messaging Intervention For Latino Smokers., Francisco Cartujano-Barrera, Lisa Sanderson Cox, Evelyn Arana-Chicas, Mariana Ramírez, Jaime Perales-Puchalt, Pamela Valera, Francisco J. Díaz, Delwyn Catley, Edward F. Ellerbeck, Ana Paula Cupertino

Manuscripts, Articles, Book Chapters and Other Papers

Objective: Assess the feasibility and acceptability of a culturally- and linguistically-adapted smoking cessation text messaging intervention for Latino smokers. Methods: Using a community-based strategy, 50 Latino smokers were recruited to participate in a smoking cessation pilot study. Participants received a 12-week text messaging intervention and were offered Nicotine Replacement Therapy (NRT) at no cost. We assessed biochemically verified abstinence at 12 weeks, text messaging interactivity with the program, NRT utilization, self-efficacy, therapeutic alliance, and satisfaction. Results: Participants were 44.8 years old on average (SD 9.80), and they were primarily male (66%) and had no health insurance (78%). Most of the …


“Why Wouldn’T I Use It?”: Purdue Pharmaceutical’S Push Of Pills, Gillian Fletcher Mar 2020

“Why Wouldn’T I Use It?”: Purdue Pharmaceutical’S Push Of Pills, Gillian Fletcher

English Student Scholarship

Throughout the early 1940’s to mid 1960’s, the popular habit of smoking cigarettes was not only condoned, but advertised by doctors and lawmakers. With the support of medical professionals and non-restrictive advertisement laws, the widespread use of this deadly product exploded. The ‘Big Tobacco’ industry and the federal government made enormous amounts in profit and tax revenue. Numerous similarities can be found between the advertising of cigarettes and the prescription opioid, OxyContin. ‘Big Tobacco’ and the producer of OxyContin, Purdue Pharma (Hoffman and Williams Walsh), employed incredibly similar tactics to encourage the public to use their lethal products. By controlling …


Evidence For Gene-Smoking Interactions For Hearing Loss And Deafness In Japanese American Families, Jia Y Wan, Christina Cataby, Andrew Liem, Emily Jeffrey, Trina M Norden-Krichmar, Deborah Goodman, Stephanie A Santorico, Karen L Edwards Mar 2020

Evidence For Gene-Smoking Interactions For Hearing Loss And Deafness In Japanese American Families, Jia Y Wan, Christina Cataby, Andrew Liem, Emily Jeffrey, Trina M Norden-Krichmar, Deborah Goodman, Stephanie A Santorico, Karen L Edwards

Journal Articles

BACKGROUND: This study investigated the relationship between smoking and hearing loss and deafness (HLD) and whether the relationship is modified by genetic variation. Data for these analyses was from the subset of Japanese American families collected as part of the American Diabetes Association Genetics of Non-insulin Dependent Diabetes Mellitus study. Logistic regression with generalized estimating equations assessed the relationship between HLD and smoking. Nonparametric linkage analysis identified genetic regions harboring HLD susceptibility genes and ordered subset analysis was used to identify regions showing evidence for gene-smoking interactions. Genetic variants within these candidate regions were then each tested for interaction with …


Socioeconomic Status Impact On Smoking Rates In Ohio In 2019, Zafer Sattouf Jan 2020

Socioeconomic Status Impact On Smoking Rates In Ohio In 2019, Zafer Sattouf

Scholarship in Medicine - All Papers

Objective: To study the impact of socioeconomic status on smoking. Research Questions: This research study aims to determine the impact of socioeconomic status on smoking rates across counties in Ohio in 2019. It is investigating how different variables such as education, income, and employment status are correlated with smoking rates across different counties. Methods: Correlation studies and ANOVA were conducted to show how smoking affects premature deaths and how socioeconomic indicators affect smoking rates. Results: Smoking is associated with increased numbers of premature deaths in Ohio 2019 (p < 0.001). Higher levels of education, higher income, and lower unemployment rates has been associated with lower smoking rates in Ohio 2019 (p < 0.001).


Insufficient Sleep In 2020: Where Does Ohio Stand?, Daniel Masters Jan 2020

Insufficient Sleep In 2020: Where Does Ohio Stand?, Daniel Masters

Scholarship in Medicine - All Papers

Objective: To determine the impact of insufficient sleep on premature death and mental health as well as see how the levels of insufficient sleep in Ohio compare to previous years and to other states in the US. Methods: Data on insufficient sleep, premature death, smoking, food environment index, physical inactivity, and poor mental health days was all collected from County Health Rankings and then analyzed. Results: Insufficient sleep was found to be moderately correlated to years of potential life lost in a positive manner in Ohio in 2020. Insufficient sleep has risen in Ohio from 2016 (35.76%) to 2020 (37.04%). …


The Effectiveness And Effects Of Alcohol Regulation: Evidence From India, Dara Lee Luca, Emily Owens, Gunjan Sharma Dec 2019

The Effectiveness And Effects Of Alcohol Regulation: Evidence From India, Dara Lee Luca, Emily Owens, Gunjan Sharma

WCBT Faculty Publications

We provide quasi-experimental evidence on the effects of alcohol regulation on alcohol consumption and associated public health outcomes using detailed individual level and aggregate data from India, where state-level laws regulating the minimum legal drinking age generate substantial variation in the availability of commercially produced alcohol across people of different ages. We find that despite significant law evasion, men who are legally allowed to drink are substantially more likely to consume alcohol. Further, men who are legally allowed to drink are significantly more likely to commit violence against their partners, suggesting a causal channel between alcohol consumption and domestic violence. …


The Effect Of Smoking On Kentucky’S Workforce, Michael W. Clark, Jenny A. Minier, Charles J. Courtemanche, Bethany L. Paris, Michael T. Childress Sep 2019

The Effect Of Smoking On Kentucky’S Workforce, Michael W. Clark, Jenny A. Minier, Charles J. Courtemanche, Bethany L. Paris, Michael T. Childress

CBER Research Report

Excerpt from the Executive Summary:

Smoking has been estimated to increase health care costs in the United States by $167.5 billion annually (Xu et al. 2015). In Kentucky, smoking adds $2.5 billion in health care expenditures each year. Most of these costs were paid by public programs such as Medicaid and Medicare. While these costs are significant, they represent only a portion of the costs that smoking imposes on society. Smoking also leads to poorer labor market outcomes. Smokers are more likely to be unemployed, earn lower wages, and die prematurely than non-smokers. These negative labor market effects reduce economic …


Health-Information Seeking And Intention To Quit Smoking: Do Health Beliefs Have A Mediating Role?, Soumya Upadhyay, Justin Loard, Maxim Gakh Aug 2019

Health-Information Seeking And Intention To Quit Smoking: Do Health Beliefs Have A Mediating Role?, Soumya Upadhyay, Justin Loard, Maxim Gakh

Public Health Faculty Publications

Background: Smoking is a leading cause of preventable deaths. Smoking cessation can reduce the risk of smoking-associated disease and death. But smoking cessation involves behaviour change. Existing research indicates that health-information seeking and health-promoting behaviours can be positively associated. However, in the context of smoking, the relationship between seeking health information and intending to quit smoking remains only partially understood. Aim: This study aimed to examine the relationship between seeking health information and intending to quit smoking and to determine whether this relationship is mediated by health beliefs. Methods: We used data from the fourth cycle of the US National …


Racial And Income Disparities In Health-Related Quality Of Life Among Smokers With A Quit Attempt In Louisiana, Yu-Hsiang Kao, Michael D. Celestin, Qingzhao Yu, Sarah Moody-Thomas, Krysten Jones-Winn, Tung-Sung Tseng Feb 2019

Racial And Income Disparities In Health-Related Quality Of Life Among Smokers With A Quit Attempt In Louisiana, Yu-Hsiang Kao, Michael D. Celestin, Qingzhao Yu, Sarah Moody-Thomas, Krysten Jones-Winn, Tung-Sung Tseng

School of Public Health Faculty Publications

Smoking is associated with a lower health-related quality of life (HRQOL). However, there is little information about the association between HRQOL in relation to race, income, and smoking status. The present study aimed to assess the association between HRQOL and smoking status for those of different races and income levels. This study applied a cross-sectional design using data from the 2017 patient survey of the Louisiana Tobacco Control Initiative. We obtained 1108 responses from patients at eight Louisiana public hospitals. The EuroQol (EQ-5D) US index score assessed HRQOL. Smoking status was classified into four groups: never smoked, former smoker, current …