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Selected Works

Wei Cheong Ngeow

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Articles 1 - 30 of 43

Full-Text Articles in Medicine and Health Sciences

Safe Zone For Bone Harvesting From The Interforaminal Region Of The Mandible, O. Al-Ani, P. Nambiar, K. O. Ha, W.C. Ngeow Nov 2011

Safe Zone For Bone Harvesting From The Interforaminal Region Of The Mandible, O. Al-Ani, P. Nambiar, K. O. Ha, W.C. Ngeow

Wei Cheong Ngeow

Aims: The mandibular incisive nerve can be subjected to iatrogenic injury during bone graft harvesting. Using cone beam computed tomography (CBCT), this study aims to determine a safe zone for bone graft harvesting that avoids injuring this nerve. Methods: Sixty CBCT examinations of patients were included in this study. The examinations were taken using the i-CAT CBCT imaging system, applying a standardized exposure protocol. Image reconstruction from the raw data was performed using the SimPlant dental implant software. The distances of mandibular incisive canal (MIC) to the inferior border and the labial and lingual cortices of the mandible were measured …

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Histomorphometric Changes In Repaired Mouse Sciatic Nerves Are Unaffected By The Application Of A Scar-Reducing Agent, W.C. Ngeow, S. Atkins, C. R. Morgan, A. D. Metcalfe, F. M. Boissonade, A. R. Loescher, P. P. Robinson Nov 2011

Histomorphometric Changes In Repaired Mouse Sciatic Nerves Are Unaffected By The Application Of A Scar-Reducing Agent, W.C. Ngeow, S. Atkins, C. R. Morgan, A. D. Metcalfe, F. M. Boissonade, A. R. Loescher, P. P. Robinson

Wei Cheong Ngeow

Microsurgical repair of transected peripheral nerves is compromised by the formation of scar tissue and the development of a neuroma, thereby limiting the success of regeneration. The aim of this study was to quantify histomorphometrically the structural changes in neural tissue that result from repair, and determine the effect of mannose-6-phosphate (M6P), a scar-reducing agent previously shown to enhance regeneration. In anaesthetised C57-black-6 mice, the left sciatic nerve was sectioned and repaired using four epineurial sutures. Either 100 mu L of 600 mM M6P (five animals) or 100 mu L of phosphate-buffered saline (placebo controls, five animals) was injected into …

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The Effect Of Mannose-6-Phosphate On Recovery After Sciatic Nerve Repair, W.C. Ngeow, S. Atkins, C. R. Morgan, A. D. Metcalfe, F. M. Boissonade, A. R. Loescher, P. P. Robinson Jun 2011

The Effect Of Mannose-6-Phosphate On Recovery After Sciatic Nerve Repair, W.C. Ngeow, S. Atkins, C. R. Morgan, A. D. Metcalfe, F. M. Boissonade, A. R. Loescher, P. P. Robinson

Wei Cheong Ngeow

We have determined the effect of applying Mannose-6-Phosphate (M6P), a scar reducing agent, to a site of sciatic nerve repair. In anaesthetised C57-Black-6 mice, the left sciatic nerve was sectioned and repaired using 4 epineurial sutures. Either 100 mu l of 600 mM Mannose-6-Phosphate (29 animals), or 100 mu l of phosphate buffered saline as a placebo control (29 animals), was injected into and around the nerve repair site. A further group acted as sham-operated controls. After 6 or 12 weeks of recovery the extent of regeneration was assessed electrophysiologically and the percentage area of collagen staining at the repair …

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A Comparison Between The Effects Of Three Potential Scar-Reducing Agents Applied At A Site Of Sciatic Nerve Repair, W.C. Ngeow, S. Atkins, C. R. Morgan, A. D. Metcalfe, F. M. Boissonade, A. R. Loescher, P. P. Robinson Apr 2011

A Comparison Between The Effects Of Three Potential Scar-Reducing Agents Applied At A Site Of Sciatic Nerve Repair, W.C. Ngeow, S. Atkins, C. R. Morgan, A. D. Metcalfe, F. M. Boissonade, A. R. Loescher, P. P. Robinson

Wei Cheong Ngeow

We have investigated the effect of three potential scar-reducing agents applied at a sciatic nerve repair site in C57-black-6 mice. Under anaesthesia the nerve was transected, repaired using four epineurial sutures, and 100 mu l of either triamcinolone acetonide (1 mg/100 mu l), an interleukin-10 peptide fragment: (125 ng/100 mu l or 500 ng/100 mu l) or mannose-6-phosphate (M6P, 200 mM or 600 mM) was injected into and around the nerve. After 6 weeks the extent of regeneration was assessed electrophysiologically by determining the ratio of the compound action potential (CAP) modulus evoked by electrical stimulation of the nerve 2 …

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Decompression Of Inferior Alveolar Nerve: Case Report Comment, W.C. Ngeow Mar 2011

Decompression Of Inferior Alveolar Nerve: Case Report Comment, W.C. Ngeow

Wei Cheong Ngeow

Paresthesia as a result of mechanical trauma is one of the most frequent sensory disturbances of the inferior alveolar nerve. This case report describes surgical treatment for paresthesia caused by a compressive phenomenon within the mandibular canal. The cause of the compression, a broken instrument left in the patient's mouth during previous endodontic therapy, was identified during routine radiography and computed tomography. Once the foreign object was removed by surgery, the paresthesia resolved quickly. This case highlights the potential for an iatrogenic mechanical cause of paresthesia.

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Is There A "Safety Zone" In The Mandibular Premolar Region Where Damage To The Mental Nerve Can Be Avoided If Periapical Extrusion Occurs?, W.C. Ngeow Jun 2010

Is There A "Safety Zone" In The Mandibular Premolar Region Where Damage To The Mental Nerve Can Be Avoided If Periapical Extrusion Occurs?, W.C. Ngeow

Wei Cheong Ngeow

The mandibular premolars are located close to the mental foramina (Fig. 1). As such, various events affecting these teeth, such as odontogenic infection1 and orthodontic, endodontic, periodontal or surgical misadventure, may result in neurosensory disturbance of the mental nerves.2-4 In one retrospective study, the incidence of mental paresthesia resulting from periapical infection or pathology was 0.96%. In another 0.24% of cases in the same study, mental paresthesia was a complication of root canal treatment (caused by severe overfill in one case and iatrogenic perforation of mechanical instrumentation through the root and into the mental nerve in the second case).1 The …

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Scar Less: A Review Of Methods Of Scar Reduction At Sites Of Peripheral Nerve Repair, W.C. Ngeow Mar 2010

Scar Less: A Review Of Methods Of Scar Reduction At Sites Of Peripheral Nerve Repair, W.C. Ngeow

Wei Cheong Ngeow

Scar formation is important for normal wound healing but proliferation of scar tissue from the epineurium in response to a nerve injury will result in impediment to the regenerating axons that need to traverse the repaired site. This article reviews the events that occur after peripheral nerve transection and the challenges that need to be addressed to reduce scarring in order to improve nerve regeneration. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010; 109: 357-366)

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Injection Of Botulinum Toxin Type A (Botox) Into Trigger Zone Of Trigeminal Neuralgia As A Means To Control Pain, W.C. Ngeow, R. Nair Feb 2010

Injection Of Botulinum Toxin Type A (Botox) Into Trigger Zone Of Trigeminal Neuralgia As A Means To Control Pain, W.C. Ngeow, R. Nair

Wei Cheong Ngeow

This article illustrates a case of persistent trigeminal neuralgia in a medically compromised 65-year-old female who did not respond to pharmacotherapy. She had undergone several peripheral neurectomies as well as a failed right posterior fossa exploration that resulted in a cerebrospinal fluid leak. Persistent pain over the right external nasal area and right mental region was relieved for several hours after daily injections of bupivacaine. A trial of a single dose of 100 units of botulinum toxin type A (BOTOX) diluted in 2.5 mL saline was injected into the external nasal trigger zone (60 units) and to the mental nerve …

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Numbness Of The Ear Following Inferior Alveolar Nerve Block: The Forgotten Complication, W.C. Ngeow, W. L. Chai Jul 2009

Numbness Of The Ear Following Inferior Alveolar Nerve Block: The Forgotten Complication, W.C. Ngeow, W. L. Chai

Wei Cheong Ngeow

This article presents a distant complication in the auricle following the administration of a standard inferior alveolar nerve block. The patient experienced profound numbness of the auricle on the ipsilateral side of the injection that lasted for about an hour following unintended injection to the auriculotemporal nerve.

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Craniofacial Anthropometric Norms Of Malaysian Indians, W.C. Ngeow, S. T. Aljunid Jul 2009

Craniofacial Anthropometric Norms Of Malaysian Indians, W.C. Ngeow, S. T. Aljunid

Wei Cheong Ngeow

Objective: This study was done to establish the craniofacial anthropometric norms of the young adult (18-25 years) Malaysian Indian. Materials and Methods: The study group consisted of convenient samples of 100 healthy volunteers, with equal number of female and male subjects who had no history of mixed racial-parentage. Twenty-two linear measurements were taken twice from 28 landmarks over six craniofacial regions. The methodology and evaluation of indices of the craniofacial region was adapted from Hajnis et al. Results: The minimum measurements are always contributed by the female Indian except for the nose height (n-sn), (left) eye fissure length (ex-en), upper …

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A Radiographic Study On The Visualization Of The Anterior Loop In Dentate Subjects Of Different Age Groups, W.C. Ngeow, D. D. Dionysius, H. Ishak, P. Nambiar Jun 2009

A Radiographic Study On The Visualization Of The Anterior Loop In Dentate Subjects Of Different Age Groups, W.C. Ngeow, D. D. Dionysius, H. Ishak, P. Nambiar

Wei Cheong Ngeow

The anterior loop is defined as where the mental neurovascular bundle crosses anterior to the mental foramen then doubles back to exit the mental foramen. It cannot be seen clinically but can be detected in 11-60% of panoramic radiographs. As this anatomical structure is important in determining the placement position of endosseous implants in the mandibular premolar region, a pilot study was undertaken to determine its visibility on dental panoramic radiographs in dentate subjects of various age groups. One or more anterior loops were visible in 39 (40.2%) radiographs encompassing 66 sites (34.4%). Interestingly, anterior loops were most commonly observed …

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Craniofacial Anthropometric Norms Of Malays, W.C. Ngeow, S. T. Aljunid May 2009

Craniofacial Anthropometric Norms Of Malays, W.C. Ngeow, S. T. Aljunid

Wei Cheong Ngeow

Introduction: This study was undertaken to establish the craniofacial anthropometric norms of young adult Malaysian Malays. Methods: The study group consisted of convenient samples of 100 healthy volunteers (aged 18-25 years), with an equal number of female and male subjects who had no history of mixed racial parentage. 22 linear measurements were taken twice from 22 landmarks over six craniofacial regions. Results: The Malays shared many similar sizes of measurements with the Singaporean Chinese. Their left eye fissure length and mouth width (ch-ch) were almost identical for both genders. However, Malay females had an upper lip height (sn-sto) (left) and …

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Managing Complications Of Radiation Therapy In Head And Neck Cancer Patients: Part Ii. Management Of Radiation-Induced Caries, W. L. Chai, W.C. Ngeow, R. Ramli, R. A. Rahman Dec 2006

Managing Complications Of Radiation Therapy In Head And Neck Cancer Patients: Part Ii. Management Of Radiation-Induced Caries, W. L. Chai, W.C. Ngeow, R. Ramli, R. A. Rahman

Wei Cheong Ngeow

Head and neck cancer is becoming a more recognizable pathology to the general population and dentists. The modes of treatment include surgery and/or radiation therapy. Where possible, pretreatment dental assessment shall be provided for these patients before they undergo radiation therapy. There are occasions, however, whereby head and neck cancer patients are not prepared optimally for radiation therapy. Because of this, they succumb to complicated oral complications after radiation therapy. The management of xerostomia has been reviewed in Part I of this series. In this article, the management of dental caries, a sequalae of xerostomia following radiation therapy is reviewed. …

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Managing Complications Of Radiation Therapy In Head And Neck Cancer Patients: Part I. Management Of Xerostomia, W.C. Ngeow, W. L. Chai, R. A. Rahman, R. Ramli Dec 2006

Managing Complications Of Radiation Therapy In Head And Neck Cancer Patients: Part I. Management Of Xerostomia, W.C. Ngeow, W. L. Chai, R. A. Rahman, R. Ramli

Wei Cheong Ngeow

Head and neck cancer is becoming a more recognizable pathology to the general population and dentists. The modes of treatment include surgery and/or radiation therapy. Where possible, pretreatment dental assessment shall be provided for these patients before they receive radiation therapy. There are occasions, however, whereby head and neck cancer patients are not prepared optimally for radiation therapy. Because of this, they succumb to complicated oral adverse effects after radiation therapy. Part I of this series reviews the management of xerostomia. The management of the effect of xerostomia to the dentition/oral cavity is discussed in Part II. © 2006 Elsevier. …

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Managing Complications Of Radiation Therapy In Head And Neck Cancer Patients: Part V. Management Of Mucositis, W.C. Ngeow, W. L. Chai, R. A. Rahman, R. Ramli Dec 2006

Managing Complications Of Radiation Therapy In Head And Neck Cancer Patients: Part V. Management Of Mucositis, W.C. Ngeow, W. L. Chai, R. A. Rahman, R. Ramli

Wei Cheong Ngeow

Head and neck cancer is becoming a more recognizable pathology to the general population and dentists. The modes of treatment include surgery and/or radiation therapy. Where possible, pretreatment dental assessment shall be provided for these patients before they undergo radiation therapy. There are occasions, however, whereby head and neck cancer patients are not prepared optimally for radiation therapy. Because of this, they succumb to complicated oral adverse effects after radiation therapy. The second last part of this series reviews and discusses the management of complication that commonly occur to the oral mucosa, i.e. mucositis. © 2006 Elsevier. All rights reserved.

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Managing Complications Of Radiation Therapy In Head And Neck Cancer Patients: Part Vi. Management Of Opportunistic Infections, W.C. Ngeow, W. L. Chai, R. Ramli, R. A. Rahman Dec 2006

Managing Complications Of Radiation Therapy In Head And Neck Cancer Patients: Part Vi. Management Of Opportunistic Infections, W.C. Ngeow, W. L. Chai, R. Ramli, R. A. Rahman

Wei Cheong Ngeow

Head and neck cancer is becoming a more recognizable pathology to the general population and dentists. The modes of treatment include surgery and/or radiation therapy. Where possible, pretreatment dental assessment shall be provided for these patients before they undergo radiation therapy. There are occasions, however, whereby head and neck cancer patients are not prepared optimally for radiation therapy. Because of this, they succumb to complicated oral adverse effects after radiation therapy. The last part of this series reviews the opportunistic infections that can occur to the perioral structure. Their management is briefly discussed. © 2006 Elsevier. All rights reserved.

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Managing Complications Of Radiation Therapy In Head And Neck Cancer Patients: Part Iv. Management Of Osteoradionecrosis, R. Ramli, W.C. Ngeow, R. A. Rahman, W. L. Chai Dec 2006

Managing Complications Of Radiation Therapy In Head And Neck Cancer Patients: Part Iv. Management Of Osteoradionecrosis, R. Ramli, W.C. Ngeow, R. A. Rahman, W. L. Chai

Wei Cheong Ngeow

Head and neck cancer is becoming a more recognizable pathology to the general population and dentists. The modes of treatment include surgery and/or radiation therapy. Pretreatment dental assessment should be provided for these patients before they undergo radiation therapy. There are occasions, however, whereby head and neck cancer patients are not prepared optimally and, as a result, they succumb to complicated oral adverse effects after radiation therapy. Osteoradionecrosis (ORN) is a severe debilitating condition that impairs healing due to reduction in vascularity and osteocyte population in the affected bone. This article reviews methods of treatment used to treat ORN such …

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Transient Loss Of Power Of Accommodation In 1 Eye Following Inferior Alveolar Nerve Block: Report Of 2 Cases, W.C. Ngeow, C. K. Shim, W. L. Chai Dec 2006

Transient Loss Of Power Of Accommodation In 1 Eye Following Inferior Alveolar Nerve Block: Report Of 2 Cases, W.C. Ngeow, C. K. Shim, W. L. Chai

Wei Cheong Ngeow

Unintended intravascular injection from inferior alveolar nerve blocks can result in frustrating distant complications affecting such structures as the middle ear and eyes. Possible complications affecting the eyes include blurring of vision, diplopia, mydriasis, palpebral ptosis and amaurosis ( temporary or permanent). In this article, we present a complication that has been reported only rarely. Two patients developed transient loss of power of accommodation of the eye resulting in blurred vision after routine inferior alveolar nerve blocks on the ipsilateral side. Clear vision returned within 10 - 15 minutes after completion of the blocks. The possible explanation for this phenomenon …

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Managing Complications Of Radiation Therapy In Head And Neck Cancer Patients: Part Iii. Provision Of Dentures, R. A. Rahman, W.C. Ngeow, W. L. Chai, R. Ramli Dec 2006

Managing Complications Of Radiation Therapy In Head And Neck Cancer Patients: Part Iii. Provision Of Dentures, R. A. Rahman, W.C. Ngeow, W. L. Chai, R. Ramli

Wei Cheong Ngeow

Head and neck cancer is becoming a more recognizable pathology to the general population and dentists. The modes of treatment include surgery and/or radiation therapy. Pretreatment dental assessment should be provided for these patients before they undergo radiation therapy. There are occasions, however, whereby head and neck cancer patients are not prepared optimally and, as a result, they succumb to complicated oral adverse effects after radiation therapy. The management of radiation-induced caries, a sequelae of xerostomia has been reviewed in Part II of this series. In this article, the management of difficulty with dentures, another sequelae of xerostomia following radiation …

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Disposable Carrier For Retrograde Fillings, W.C. Ngeow, W. L. Chai Jan 2006

Disposable Carrier For Retrograde Fillings, W.C. Ngeow, W. L. Chai

Wei Cheong Ngeow

Commercially available retrograde filling carriers are delicate and easily damaged by pressure. In addition, they are difficult to clean and keep free from blockage. This report describes a simple and easy technique for transforming a standard disposable hypodermic syringe and needle into a disposable carrier for retrograde fillings. © 2006 Asian Association of Oral and Maxillofacial Surgeons.

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Proliferative And Apoptotic Activity At The Tumour Invasive Front In Oral Squamous Cell Carcinoma, W.C. Ngeow, R. B. Zain, Z. Abidin, K. S. Phaik, S. Kumar Apr 2005

Proliferative And Apoptotic Activity At The Tumour Invasive Front In Oral Squamous Cell Carcinoma, W.C. Ngeow, R. B. Zain, Z. Abidin, K. S. Phaik, S. Kumar

Wei Cheong Ngeow

Introduction: the tumour invasive front of squamous cell carcinoma (OSCC) has long been recognized as an important area which harbour prognostic information. The aim of the present study was to describe the expression of K1-67, MDM2 and Bcl-2 at the tumour invasive front in the buccal mucosa and also to investigate whether there is any association between the expression of K1-67, MDM2 and Bcl-2 with the certain sociodemographic characteristics, clinical and histopathological parameters. Materials and Methods: The sample of this study consisted of 31 biopsy cases of OSCC from the buccal mucosa. Immunohistochemistry was used with specific antibodies to K1-67, …

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The Location Of The Mental Foramen In A Selected Malay Population, W.C. Ngeow, Y. Yuzawati Sep 2003

The Location Of The Mental Foramen In A Selected Malay Population, W.C. Ngeow, Y. Yuzawati

Wei Cheong Ngeow

Knowledge of the position of the mental foramen is important both when administering regional anesthesia and performing periapical surgery in the mental region of the mandible. This study determines the position of the mental foramen in a selected Malay population. One hundred and sixty nine panoramic radiographs of Malay patients retrieved from a minor oral surgery waiting list were selected to identify the normal range for the position of the mental foramen. The foramen was not included in the study if there was any mandibular tooth missing between the lower left and right first molars (36-46). The findings indicated the …

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Satisfaction Of Orthognathic Surgical Patients In A Malaysian Population, K. K. Siow, S. T. Ong, C. B. Lian, W.C. Ngeow Dec 2002

Satisfaction Of Orthognathic Surgical Patients In A Malaysian Population, K. K. Siow, S. T. Ong, C. B. Lian, W.C. Ngeow

Wei Cheong Ngeow

Thirty-one patients treated at the Faculty of Dentistry, University of Malaya, were assessed for their satisfaction following orthognathic surgery. The female to male ratio was 22:9 with an age range of 17 to 36. Almost all patients (97%) listed appearance as one of their rationales for surgery. More males (78%) than females (59%) wanted functional improvement, while more females (91%) than males (33%) hoped for improvement in self-confidence. All patients reported esthetic improvement while 68% each reported improvement in mastication and self-confidence. Slightly more than half (52%) chose esthetic improvement as the single most important factor resulting in satisfaction. Almost …

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Orthognathic Surgery In The University Of Malaya, W.C. Ngeow, S. T. Ong, K. K. Siow, C. B. Ian Dec 2002

Orthognathic Surgery In The University Of Malaya, W.C. Ngeow, S. T. Ong, K. K. Siow, C. B. Ian

Wei Cheong Ngeow

This is the first review on orthognathic surgery in Malaysia. The records of a total of 84 patients seen between 1977 and 1999 in the Department of Oral and Maxillofacial Surgery of the Faculty of Dentistry, University of Malaya were analysed. Skeletal III deformity formed 85% of the sample with a female dominance of 2 to 1. The patients' age ranged from 17 to 36 years, with a mean of 25.3 years. The common surgical techniques used were combined bilateral sagittal split and Le Fort I osteotomy. The predominant ethnic group was Chinese (n=58, 69%); followed by Malay (n=14, 17%) …

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Malignancy In Oral Lichen Planus: A Review Of A Group From The Malaysian Population, H. B. Yaacob, P. L. Tan, W.C. Ngeow Jun 2002

Malignancy In Oral Lichen Planus: A Review Of A Group From The Malaysian Population, H. B. Yaacob, P. L. Tan, W.C. Ngeow

Wei Cheong Ngeow

The objective of this study was to determine the socio-demography (age, race and gender) of a group of Malaysian patients who were diagnosed as suffering from oral lichen planus (OLP). The occurrence of malignancy was also investigated. A total of 77 clinical and biopsy records of patients with OLP were studied. Females were affected more than males, with the female to male ratio being 2:1. Middle-aged Indian and Chinese females tend to be affected by OLP when compared with the rest of the population. Only 19 patients returned for further follow-up. One adult Indian female with a six-year history of …

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Changing Incidence Of Oral And Maxillofacial Tumours In East Java, Indonesia, 1987-1992. Part 2: Malignant Tumours, T. I. Budhy, S. D. Soenarto, H. B. Yaacob, W.C. Ngeow Dec 2001

Changing Incidence Of Oral And Maxillofacial Tumours In East Java, Indonesia, 1987-1992. Part 2: Malignant Tumours, T. I. Budhy, S. D. Soenarto, H. B. Yaacob, W.C. Ngeow

Wei Cheong Ngeow

A total of 2193 tumours of the mouth and jaw diagnosed at the Laboratorium Patologi Anatomi Fakultas Kedokteran Universitas Airlangga, Indonesia from 1987 to 1992, inclusive, was studied. Malignant tumours constituted 45.3% of the lesions. Almost 71% of the malignant tumours were squamous cell carcinomas. The remainder were salivary gland tumours (21.5%) and sarcomas (4.5%). The male to female ratio for malignant tumours was 5.1:4.7. The incidence of malignant tumours per 100,000 population over the 6-year study period was 2.64. The yearly incidence seemed to increase except in 1990, when it dropped. The incidence of squamous cell carcinoma over the …

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Unusual Tooth Sensation Due To Maxillary Sinusitis--A Case Report, W.C. Ngeow Jan 2000

Unusual Tooth Sensation Due To Maxillary Sinusitis--A Case Report, W.C. Ngeow

Wei Cheong Ngeow

Maxillary sinusitis can cause pain or discomfort to the maxillary dentition but no report of patients complaining of a "jumping tooth sensation" during sinusitis has been recorded in the literature. This article presents a case of an unusual localised sensation from a maxillary right second premolar experienced while undergoing root canal treatment. This sensation was felt during walking while the patient was suffering an episode of influenza. This sensation first occurred following debridement of the root canal. However, it persisted even after the root canal had been sealed. A hypothetical explanation of this manifestation is proposed.

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Red Man Syndrome During Administration Of Prophylactic Antibiotic Against Infective Endocarditis, W.C. Ngeow, W. L. Chai, A. B. Moody Jan 2000

Red Man Syndrome During Administration Of Prophylactic Antibiotic Against Infective Endocarditis, W.C. Ngeow, W. L. Chai, A. B. Moody

Wei Cheong Ngeow

Red man syndrome (RMS) is the occurrence flushing, pruritus, chest pain, muscle spasm or hypotension during vancomycin infusion. It usually happens as a result of rapid infusion of the drug but may also occur after slow administration. The frequency and severity of this phenomenon diminish with repeated administration of vancomycin. A case is presented whereby RMS occurred while prophylactic antibiotic against infective endocarditis was administered.

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Familial Cases Of Missing Mandibular Incisor: Three Case Presentations, W. L. Chai, W.C. Ngeow Sep 1999

Familial Cases Of Missing Mandibular Incisor: Three Case Presentations, W. L. Chai, W.C. Ngeow

Wei Cheong Ngeow

Hypodontia is the congenital absence of one or more teeth because of agenesis. The most commonly missing teeth are the third molars, the maxillary lateral incisors and the second premolars. Cases are presented of three patients with a missing mandibular incisor.

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Clinicopathologic Study Of Odontogenic Keratocysts In Singapore And Malaysia, W.C. Ngeow, R. B. Zain, J. F. Yeo, W. L. Chai May 1999

Clinicopathologic Study Of Odontogenic Keratocysts In Singapore And Malaysia, W.C. Ngeow, R. B. Zain, J. F. Yeo, W. L. Chai

Wei Cheong Ngeow

This was a retrospective study of odontogenic keratocysts in people from the Singapore-Malaysian region. The purpose of this study was to present the clinicopathologic features of odontogenic keratocysts in the Oriental population and to compare these data with those from other reported studies. Biopsy records from 1981 to 1992 of 61 cases of odontogenic keratocysts from patients in Malaysia and Singapore showed that 42.6% of patients were female and 57.4% of patients were male. Among patients with cysts, 75.4% were Chinese, 6.6% were Malays, 9.8% were Indians and 8.2% were other ethnic groups. The mean age of these patients was …

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