Medicine and Health Sciences Commons^™

Short And Prolonged Fasting Prior To The Performance Of Tracheostomies In Intensive Therapy: A Retrospective Study, Lucas Gonzalo Duran, María Emilia Beilman, Araceli Natali Quiroga, Magdalena Cruz, Alejandra Vanesa Millan, Micaela Johanna Ojeda, Fabiana Ciccioli, Micaela Giselle Montenegro Fernandez, Wendy Estefany Monrroy Miro, Valentina Trinidad Malisia, Nicolas Antonio Grassi, Nazareno Iñaki Zelaya De Leon, Franco Ezequiel Espinoza, Marina Otamendi, Paula Zorzano Osinalde, Marcos Petasny

Revista de la Facultad de Medicina Humana

Introduction: International guidelines on aid prior to invasive procedures usually generate longer aid than in intensive care (IT) patients. This fact represents a high risk of malnutrition and, consequently, a worse prognosis. The objective of the present investigation was to analyze the degree of association between the fasting time prior to tracheostomy of patients under mechanical ventilatory assistance (MVA) and the appearance of pneumonia. Methods: Retrospective cohort study that included patients admitted to our IT from 10/01/2018 to 08/31/2022 and with a tracheostomy performed. Two cohorts were defined characterized by fasting ≤3 hours vs. >3 hours. Fisher's exact test and …

Use Of Inhaled Corticoids As A Risk Factor For Community-Acquired Pneumonia In Patients With Chronic Obstructive Pulmonary Disease, María Alejandra Castillo Vega, Gilmar Robert Mejía Sánchez

Revista de la Facultad de Medicina Humana

Objective: To determine if the use of inhaled corticosteroids is a risk factor for community-acquired pneumonia in patients with Chronic Obstructive Pulmonary Disease at the Víctor Lazarte Echegaray Hospital during the period 2017-2020. Methods: The study was analytical, observational, retrospective of cases and unmatched controls in a ratio of 4:1 with a population of 405 subjects from whom 81 cases and 324 controls were selected, who met the selection criteria. A non-probabilistic sampling was carried out. The variables, use of inhaled corticosteroids, patients with community-acquired pneumonia, age, sex, malnutrition and smoking were included. The association measure was made using Pearson's …

Comprehensive Comparison Of Clinicoradiological, Laboratory, And Prognostic Factors Of Community-Acquired Pneumonia In Diabetic And Nondiabetic Hospitalized Patients, Seyyed Hamid Hashemi, Fatemeh Saki, Shiva Borzouei, Rashed Bawand, Alireza Soltanian

Turkish Journal of Medical Sciences

Background/aim: Community-acquired pneumonia (CAP) is one of the leading infectious causes of mortality, and diabetes mellitus is a globally prevalent disease. Consequently, the cooccurrence of these two disorders can be common and create challenging medical conditions. Therefore, it was aimed to compare the various aspects of CAP in diabetic and nondiabetic patients, in order to have a comprehensive and comparative picture of the differences. Materials and methods: In this cross-sectional study, CAP patients with and without diabetes were assessed for clinicoradiological signs, laboratory features, disease severity, and pneumonia outcomes. Results: Analyzed herein were 172 CAP patients (77 had diabetes and …

Comparison Of Microbial Respiratory Cultures Versus Mrsa Nasal Screen To Guide Vancomycin De-Escalation In Patients Hospitalized For Bacterial Pneumonia, Victoria E. Grusauskas, Anthony Wasielewski, Kristin Boyar

Nursing & Health Sciences Research Journal

Background: Methicillin-resistant Staphylococcus aureus (MRSA) nasal screen identifies the presence of MRSA nasal colonization, which can be used as a valuable antimicrobial stewardship tool to de-escalate empiric vancomycin therapy in patients with pneumonia. Current practices at a Florida hospital include using respiratory culture and MRSA nasal screening results to assist in treating MRSA pneumonia infections. This study aimed to evaluate the total duration of vancomycin therapy in patients with suspected MRSA respiratory tract infections. Methods: This was a single-center, retrospective chart review conducted at a tertiary medical center. Adult patients were assigned to either the respiratory culture-directed group or the …

Role Of Transthoracic Ultrasound In Diagnosis And Follow-Up Of Pneumonia, Hanaa A. Eid, Mai M. El-Kalashy, Ahmed A. Elesdoudy, Zeinab A. Kasemy, Amal A. El-Koa

Menoufia Medical Journal

Objectives: To assess the role of transthoracic ultrasound (TUS) in the diagnosis and follow-up of pneumonia compared to CXR and HRCT. Background: Pneumonia is a serious health problem. TUS is quickly becoming one of the most useful non-ionizing radiation diagnostic techniques for identifying various lung illnesses. Methods: This prospective observational study was carried out in the Menoufia University Hospitals' Chest Diseases Department. From December 2022 to June 2023, it covered 50 patients who were clinically suspected of having pneumonia. The diagnosis was based on symptoms, signs, and chest HRCT. TUS and chest X-ray (CXR) were done and follow-up TUS after …

Diagnostic Value Of Multidetector Computed Tomography In Assessment Of Different Patterns Of Coronavirus Disease 2019 Pneumonia, Dena M. Serag, Amany F. Abd El Kader Salim, Waleed A. Mousa

Menoufia Medical Journal

Objective

To highlight the diagnostic value of multidetector computed tomography (CT) in the assessment of different patterns of coronavirus disease 2019 (COVID-19) pneumonia to help in proper and accurate diagnosis.

Background

As worldwide health care system has been overwhelmed by a novel COVID-19, early identification of risks of adverse outcomes becomes the key to optimize management.

Patients and methods

This prospective study was conducted on 250 patients finally diagnosed as having COVID-19 pneumonia by PCR. Those patients were recruited from the outpatient clinic and isolation unit of Menoufia University Hospital and the outpatient clinics of Shebin Elkom Fever Hospital.

Results …

Mortality Rate Risk Factors In Neonatal Intensive Care Units In El Giza Governorate, Ghada M. Elmashad, Shimaa A. Ibrahim, Hanan M. Elsayed

Menoufia Medical Journal

Objective: This study aimed to determine the incidence of neonatal mortality percentage in NICUs in Giza Governorate hospitals for early prediction of the disease.

Background: Neonatal mortality rates defined as death of a live born newborn within the first 28 days vary greatly between countries, even within high-income countries.

Methods: A retrospective study was conducted on 155 Egyptian neonates aged from 1 day up to 4 weeks to evaluate the risk factors of the mortality rates at Giza Governorate hospitals NICU during the period from August 2021 to December 2021.

Results: We reported about 6.5% of the studied neonates experienced …

Risk Factor Analysis Of Hospital Readmissions At St. Petersburg General Hospital, Vincent Wu, Sean Quinonez, My Myers, Kyle Borodunovich, Aisha Shamsi, Patrick Stocker, Bryan Fink, Steven Ferreira

HCA Healthcare Journal of Medicine

Background

Decreased readmission rates are largely seen as an indicator of effective care and improved resource management. The case management team at St. Petersburg General Hospital in St. Petersburg, Florida identified chronic obstructive pulmonary disease (COPD) exacerbation, pneumonia, and sepsis as 3 of the leading diagnoses on index admission that later led to 30-day readmissions. By examining patients with these 3 diagnoses on index admission, we decided to investigate potential readmission risk factors including patient age, sex, race, body mass index (BMI), length of stay during the index admission, insurance type during index admission, discharge placement after index admission, coronary …

Early Diagnostic Value Of Lung Ultrasound Compared To Chest Computed Tomography For Pleural Effusion And Pneumonia In Critically Ill Patients, Mohamed Osman Abdel Hamid Ibrahim, Mostafa Abdel Hamid Abo-Elainin, Khalid Mohamed Halima, Mohamed Abdelgawad Aboelsuod

Al-Azhar International Medical Journal

Background: Recently, lung ultrasound has been touted as a modality that can diagnose pneumonia in a variety of settings while overcoming many of the shortcomings of other tools. Aim: The aim of the study to compare between diagnostic value of lung ultrasound and CT- chest in evaluating pneumonia and pleural effusion in ICU patients. The primary study outcomes were the sensitivity and specificity of lung ultrasound and CT-chest in pneumonia and pleural effusion. The Secondary study outcomes were the satisfaction of the patient. Patients and Methods: This was observational study included 40 patients admitted to ICU Al-Azhar university hospitals. Results: …

Covid-19 Vaccine Effectiveness In Preventing Severe Infections And Mortality Among Patients In Kerala, India., Surag Mk, Sarin S. M, Sarosh Kumar K K, Udaya A

Digital Journal of Clinical Medicine

ABSTRACT

Background:

India has a top status among world countries, related to the COVID-19 mortality that had crossed the 3-lakh level. The second wave of COVID19 had ravaged the world countries, created havoc of the highest order, leaving many hapless, thanks to the low availability of oxygen, ICU facilities, vaccines and counselling prospects.

There is a lack of information about how COVID-19 vaccines have affected mortality in specific geographic areas.

Method:

A Retrospective record-based design. Patients were matched for age, sex, ethnicity, co-morbidities and grouped into fully immunized, partially immunized and non-immunized.

The primary outcome was in-hospital deaths and secondary …

Antimicrobial Stewardship Meets Transitions Of Care: Defining Length Of Therapy For Community-Acquired Pneumonia (Cap), Christopher Whitman, Sarah E. Moore Pharmd, Matthew Song Pharmd, Bcidp, Brian C. Bohn Pharmd, Bcidp, Ashley M. Wilde

The University of Louisville Journal of Respiratory Infections

Introduction: Hospital-based antimicrobial stewardship efforts have traditionally focused on inpatient settings. Antibiotic prescribing at discharge is often an overlooked area of focus for antimicrobial stewardship programs. Discharge prescribing optimization is necessary to combat antibiotic overuse.

Methods: This was an observational, retrospective cohort study at a four–adult community hospital system. Four hundred adult patients admitted with community-acquired pneumonia and discharged with antibiotics were included. The primary outcome was overall (inpatient and discharge) antibiotic length of therapy. The secondary outcome was percentage of patients discharged on a fluoroquinolone who had not received one in the hospital. Descriptive statistics were utilized.

Results: The …

Covid-19, Vaccination, And Heart Transplantation, Forest W. Arnold

The University of Louisville Journal of Respiratory Infections

No abstract provided.

Covid-19 Case Complicated With Organizing Pneumonia And Pneumothorax: A Case Report, Tammy E. Phillips, Hammad A. Bhatti, Minh Q. Ho

The University of Louisville Journal of Respiratory Infections

Organizing pneumonia can be idiopathic or caused by multiple etiologies, including viral or bacterial pneumonia, drugs, and autoimmune disorders. It can rarely lead to cyst formation and pneumothorax with the exact mechanism remaining unclear. This case presents a previously healthy 50-year-old male who contracted COVID-19 with subsequent development of organizing pneumonia and pneumothorax. Patients presenting with hypoxic respiratory failure due to COVID-19 should be screened for organizing pneumonia upon discharge. This case also illustrates the importance of following such patients radiologically to monitor interstitial lung disease and consider pneumothorax for patients re-presenting with acute symptoms.

Association Of Natural Waterways And Legionella Pneumophila Infection In Eastern Wisconsin: A Case-Control Study, Hannah M. William, Kayla Heslin, Jessica J. F. Kram, Caroline P. Toberna, Dennis J. Baumgardner

Journal of Patient-Centered Research and Reviews

Preliminary research has suggested possible associations between natural waterways and Legionella infection, and we previously explored these associations in eastern Wisconsin using positive L. pneumophila serogroup 1 urine antigen tests (LUAT) as diagnostic. This case-control study was a secondary analysis of home address data from patients who underwent LUAT at a single eastern Wisconsin health system from 2013 to 2017. Only zip codes within the health system’s catchment area that registered ≥ 3 positive cases and ≥ 50 completed tests, as well as geographically adjacent zip codes with ≥ 2 positive cases and ≥ 50 tests, were included. A 1:3 …

Prevalence Of Infectious Diseases Among 6078 Individuals With Down Syndrome In The United States, Veronica Fitzpatrick, Anne Rivelli, Sagar Chaudhari, Laura Chicoine, Gengjie Jia, Andrey Rzhetsky, Brian Chicoine

Journal of Patient-Centered Research and Reviews

A recent disease prevalence study of the largest documented Down syndrome (DS) cohort in the United States strongly suggested significant disparity in general infectious disease conditions among individuals with DS versus those without DS. In this follow-up retrospective analysis, we explored these differences in greater detail by calculating prevalence of 52 infectious diseases, across 28 years of data among 6078 individuals with DS and 30,326 age- and sex-matched controls, abstracted from electronic medical records within a large Midwestern health system. We found that the DS cohort had higher prevalence of pneumonias (including aspiration, viral, bacterial, pneumococcal, and unspecified/atypical); otitis externa; …

Clinical And Imaging Findings Of Patients Diagnosed With Adenovirus-Positivepneumonia During 2015-2019 In Shanghai, China, Chunrong Huang, Dong Wei, Yahui Liu, Guo Chao Shi

Turkish Journal of Medical Sciences

Background/aim: This study was to describe the clinical characteristics, chest CT image findings, and potential role of T cells immunity in adenovirus positive pneumonia. Materials/methods: In this retrospective study, medical records of 53 adult Adv+ patients who were admitted to the Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, from May 2015 to August 2019 were included. The presence of adenovirus and other respiratory viruses was detected using polymerase chain reaction of throat swabs samples. Clinical features and chest computed tomography (CT) findings were compared between patients with Adv+ pneumonia and Adv+ non-pneumonia. Results: The top 3 most commonly …

Flu And Pneumonia Coverage Of Lesbian, Gay, Bisexual, And/Or Transgender Individuals, Brandi W. Fruin, Cathy H. Abell, Maria E. Main

International Journal of Faith Community Nursing

Abstract

Background: Population health is important in examining health outcomes of specific groups. The lesbian, gay, bisexual, and transgender community is a vulnerable population continuing to endure health disparities.

Purpose: The purpose of this part of a larger study was to examine the self-reported flu/pneumonia coverage in individuals self-identifying as lesbian, gay, bisexual, and/or transgender

Methodology: A purposeful sample and select items from the Behavioral Risk Factor Surveillance Survey were utilized.

Findings: Findings included almost half of respondents indicating obtaining a flu shot or vaccine and approximately one-fourth of the respondents reported receiving a pneumonia shot/vaccine.

Recommendations: Ongoing education …

Association Of Lung Cancer With Pneumonia And Chlamydia Pneumoniae Infection, Johnny Zakhour Md, Daniel Muller, Alex Glynn, Jose Bordon

The University of Louisville Journal of Respiratory Infections

Introduction: The degree of association and type of causal versus non-causal relationship between pneumonia and lung cancer (LC) are evolving discussions. We reviewed English publications on the degree of association between pneumonia and subsequent LC.

Methods: We searched the PubMed database using key words for pneumonia, LC, and chlamydia infection. We selected peer-reviewed studies of patients with pneumonia and LC. Case reports and other literature reviews were excluded from this review.

Results: Five studies examined the incidence and/or risk of LC for a total of 415,750 patients, and four studies examined cases with Chlamydia pneumoniae chronic infection at the time …

Reversible Pulmonary Hypertension Secondary To Bronchopneumonia In A Kitten, Jidapa Tosuwan, Sirilak Disatian Surachetpong

The Thai Journal of Veterinary Medicine

A five-month-old Siamese kitten was presented with acute respiratory distress. The kitten had respiratory acidosis. The result of the feline N-terminal prohormone of brain natriuretic peptide (NT-proBNP) test kit was abnormal. Thoracic radiography revealed patchy lung infiltration and cardiomegaly. Severe right heart enlargement and an intermediate probability of pulmonary hypertension were suggested from echocardiography. Pulmonary hypertension secondary to severe pneumonia was suspected. The kitten was treated with oxygen supplementation, antibiotics and pimobendan. The clinical signs, radiography and echocardiography returned to normal after 30 days of treatment.

No Difference In Clinical Outcomes For African American And White Patients Hospitalized With Sars-Cov-2 Pneumonia In Louisville, Kentucky, Julio A. Ramirez, Stephen P. Furmanek, Thomas Chandler, Stephen S. Hanson, Dawn Balcom, Subathra Marimuthu, Sathya Krishnasamy, Jose Bordon, Rodrigo Cavallazzi, Amr Aboelnasr, Mahder A. Tella, William A. Mattingly, Ashley M. Wilde, Daisy Sangroula, Demetra Antimisiaris, Donghoon Chung, Guillermo Cabral, Gabino R Fernandez-Botran, Jiapeng Huang, Martin Gnoni, Ozan Akca, Paul Schulz, Phillip F. Bressoud, Priya Krishnan, Sally Suliman, William P. Mckinney, Bryan Moffett, Leslie A Wolf, Mark Burns, Alex Glynn, Ruth Carrico, Forest W. Arnold

The University of Louisville Journal of Respiratory Infections

Introduction: Current literature indicates that African American individuals are at increased risk of becoming infected with the SARS-CoV-2 virus and suffer higher SARS-CoV-2-related mortality rates. However, there is a lack of consensus as to how the clinical outcomes of African American patients differ from those of other groups. The objective of this study was to define the clinical outcomes of African American and White hospitalized patients with SARS-CoV-2 community-acquired pneumonia (CAP) in Louisville, Kentucky.

Methods: This was a retrospective cohort study of hospitalized patients with SARS-CoV-2 CAP at eight hospitals in Louisville, Kentucky. Severity of CAP at time of hospitalization …

A Review On Corona Virus Disease (Covid-19), Hatem Hejaz, Dalia Abo Arqoup, Rezq Basheer, Hiba Abu Znaid, Hiba Swaity, Thara’A Thara’A Rabai

Hebron University Research Journal-A (Natural Sciences) - (مجلة جامعة الخليل للبحوث- أ (العلوم الطبيعيه

Novel Coronavirus (COVID-19) is a new strain of coronavirus that may cause illness in animals or humans. SARS-CoV-2 was first identified in late December 2019, in Wuhan, China. The coronavirus infected patients ‘who suffering from Immundeficient or chronic inflammation are at higher risk of getting a severe infection from COVID-19. The symptoms such as proinflammatory and hypercoagulable, non-cardiac pneumonia, multi-organ failure, and ARDS resulting in sudden death have been seen in those patients. Supportive treatment is still the main strategy in treating this disease since there is no evidence that current medicine can prevent or cure the infection resulting from …

Baricitinib In The Treatment Of A Critical Patient With Covid-19 Pneumonia: A Case Report, Nishant Patel, Dylan Goldsmith, Forest W. Arnold

The University of Louisville Journal of Respiratory Infections

A 72-year-old male presented to the emergency department with a chief complaint of diarrhea after having tested positive for COVID-19 two days prior. He initially had minimal respiratory complaints, but was eventually transferred to the intensive care unit for acute hypoxic respiratory failure. In addition to dexamethasone, remdesivir, and antibiotics, the patient was treated with baricitinib, a Janus kinase inhibitor that was recently granted emergency use authorization by the Food and Drug Administration for treatment of hospitalized patients with COVID-19. He had an extensive and complicated hospital course and had to be placed on mechanical ventilation, ultimately undergoing tracheostomy. After …

The Population Affected By The Syndemic Of Covid-19 And Poverty Is More Likely To Be Hospitalized With Sars-Cov-2 Pneumonia, Julio A. Ramirez, Stephen P. Furmanek, Meredith Cahill, Stephen S. Hanson, Ruth Carrico, Forest W. Arnold

The University of Louisville Journal of Respiratory Infections

Background

Lockdown measures to control COVID-19 have exacerbated the poverty epidemic. We hypothesized that the synergistic interaction of COVID-19 and poverty epidemics favors the development of more severe forms of COVID-19 in the population living in poverty. To test this hypothesis, we assessed whether an ecological association exists between the geographic distribution of hospitalized patients with SARS-CoV-2 pneumonia and markers of poverty in the city of Louisville, KY.

Methods

Using the geomasked home addresses of hospitalized patients with SARS-CoV-2 pneumonia in the city of Louisville, a kernel density heatmap was created. Kuldorff’s spatial scan statistic was used to calculate areas …

Streptococcus Anginosus Lung Infection And Empyema: A Case Report And Review Of The Literature, Nishita Tripathi, Kuldeep Ghosh, Anupama Raghuram

The University of Louisville Journal of Respiratory Infections

Streptococcus milleri group (SMG) also referred to as the Streptococcus anginosus group. These are Gram-positive, variable hemolysis, catalase negative, microaerophilic, non-motile facultative anaerobes which have been known to cause abscesses in humans. We report a case of empyema caused by Streptococcus anginosus in a patient with an unresolved pneumonia for over a month. In early October 2018, the patient presented to an emergency room with the complaints of shortness of air, productive cough, chills, subjective fever and weight loss for 4 weeks. A chest X-ray revealed a left lower lobe pneumonia. He was treated with 250 mg of azithromycin for …

Congenital Malformation Of The Pulmonary Airway (Mcvap), Case Report, José Medina Valdivia

Revista de la Facultad de Medicina Humana

Pulmonary malformations include different abnormalities of the respiratory system, including congenital pulmonary airway malformation (MCVAP), formerly known as cystic adenomatous malformation, which is a rare disease with an incidence of 1 in 8,300 to 35,000 live births. Five classification patterns have been described according to the number and size of the cyst, in addition to their histological characteristics, with type 1 MCVAP being the most frequent, showing displacement of adjacent structures according to size, associated with brochioalveolar carcinoma, and good prognosis after resection surgical. We present the case of a four-year-old female patient with recurrent hospitalizations for pneumonia and bronchial …

Defining Early And Late Clinical Outcomes In Patients With Sars-Cov-2 Pneumonia, Julio A. Ramirez, Jose Bordon, Rodrigo Cavallazzi, Stephen P. Furmanek, Jiapeng Huang, Timothy L. Wiemken, Forest W. Arnold

The University of Louisville Journal of Respiratory Infections

No abstract provided.

Can Thrombocytosis Or Thrombocytopenia Predict Complicated Clinical Course And30-Days Mortality In Patients With Pneumonia?, Razi̇ye Si̇nem Misirlioğlu, Ersi̇n Aksay, Emre Şanci, Kemal Can Tertemi̇z

Turkish Journal of Medical Sciences

Background/aim: While several different scoring systems aim to determine the clinical outcomes for patients with pneumonia, there is limited emphasis on the platelet count. This study investigated the relationships between thrombocyte count and 30-day mortality and complicated clinical course of patients with pneumonia. Materials and methods: This prospective cross-sectional study enrolled patients over 18 years old with a diagnosis of pneumonia in the emergency department for six months. The primary outcome was to establish the relationship between platelet count, mortality, complicated clinical course, and initial vital parameters on admission. The secondary outcome was comparing the platelet count with mortality and …

Investigation Of The Nontypical Pasteurella Multocida Strains Obtained From Multiple Sources, Regions, And Times: An Unexpected Increase Was Detected, Asli Sakmanoğlu, Ali̇ Uslu, Zafer Sayin, Yasemi̇n Karyeyen, Gökçenur Sani̇oğlu Gölen, Ayşegül İlban, Beatri̇z Padron-Perez, Mustafa Agah Teki̇ndal, Osman Ergani̇ş

Turkish Journal of Veterinary & Animal Sciences

In this study, it was aimed to isolate Pasteurella multocida from 1250 lung samples (calf, sheep, and goat), with respiratory system infection, such as nasal discharge, cough, fever, and to investigate the phenotypic and genotypic properties of this bacteria. As a result, a total of 92 P. multocida were obtained, of which 66 (71.73%) were from calf, 19 (20.65%) from sheep, and 7 (7.6%) from goat. The A:3A type was the most common type with 34 isolates (36.95%), including 30 from calves (45.45%), and 4 from sheep (21.05%). An alternate mPCR protocol was developed to determine capB and capE genes …

Evaluation Of The Chest Computed Tomography And Hemogram Data In Patients Withcovid-19: The Importance Of Thymus, Vefa Çakmak, Atakan Yilmaz, Tuğba Sari, Pinar Çakmak, Mert Özen, Duygu Herek, Alten Oskay

Turkish Journal of Medical Sciences

Background/aim: To investigate the relationship between imaging findings and peripheral blood cell counts of COVID-19 patients and the degree of thymus fat involution of these patients. Materials and methods: Computed tomography (CT) images of 87 patients with COVID-19 positive through RT-PCR testing were evaluated retrospectively by two radiologists. Ground glass densities and other signs of viral pneumonia were recorded, lung involvement was scored quantitatively. The patients thymus fat involution was graded on CT. Neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratios (PLR), lymphocyte and platelet counts were calculated. Imaging findings and degrees of thymus fat involution were compared with laboratory data. Results: Quantitative …

The Comparison Of Favipiravir And Lopinavir/Ritonavir Combination In Covid-19treatment, Hali̇t Çinarka, Gülşah Günlüoğlu, Mustafa Çörtük, Si̇bel Yurt, Murat Kiyik, Ayşe Fi̇li̇z Koşar, Eli̇f Tanriverdi̇, Meli̇h Akay Arslan, Kürşad Nuri̇ Baydi̇li̇, Aysu Si̇nem Koç, Sedat Altin, Erdoğan Çeti̇nkaya

Turkish Journal of Medical Sciences

Background/aim: SARS-CoV-2, a ribonucleic acid coronavirus, rapidly spread worldwide within a short timeframe. Although different antiviral, antiinflammatory, and immunomodulatory drugs are used, current evidence is insufficient as to which drug is more efficient. Our study compared favipiravir and lopinavir/ritonavir (LPV/RTV) therapies in inpatient care for coronavirus disease 2019 (COVID-19) pneumonia. Materials and methods: Demographic data, test results, treatments, and latest status of patients receiving inpatient COVID-19 pneumonia therapy were recorded. The initial favipiravir and LPV/RTV receiving groups were compared regarding the need for intensive care units (ICU) and mortality. Logistic regression analysis was performed by including variables showing significant differences …