Medicine and Health Sciences Commons^™

Sars-Cov-2 Infection Complicated By Acute Pericarditis Concurrent With Malaria Infection, Kevin Hocin, Yudha Kusuma, Atit Puspitasari Dewi

Jurnal Penyakit Dalam Indonesia

Coronavirus disease 19 (COVID-19) can present as various symptoms, which range from asymptomatic to severe symptoms. We report a case of COVID-19 female patient with malaria co-infection who developed pericarditis complication. In this pandemic era, it is mandatory to rule out COVID-19. Coinfection with malaria will result in higher cytokine levels which lead to atypical complication, such as pericarditis. Prompt identification of atypical COVID-19 complications is essential as it can lower the mortality rate and reduce the duration of hospitalization.

A Debriefing Of A Student Created Malaria Board Game, Jeffrey L. Lennon

International Journal of Health Sciences Education

Purpose- This article examined the post-game debriefing of a student-created board game on the topic of malaria, taken from UNICEF and other international agencies’ Facts for Life.

Design/Methodology/Approach- A group of university health students participated in the play of the game and the debriefing. Initial debriefing of seven steps(key themes) occurred through written format, followed by an oral debriefing.

Findings – Major categories from the written debriefing by steps, key category response, and number of categories were as follows: For experience recall – how to prevent malaria, nine response categories; for feelings – felt informed, felt happy, nine response categories; …

Malaria Knowledge, Prevention Practices, And Insecticide-Treated Net Ownership And Use Among Foreign Migrants: A Survey In Four Malaria Transmission Districts Of Yala Province, Southern Thailand, Tinzar Naing, Thanapoom Rattananupong, Narin Hiransuthikul

Chulalongkorn Medical Journal

Background: Increased malaria caseload is a public health threat to malaria elimination in Southern Thailand. Yala Province has the second highest malaria caseload in the country. Cross-border migration may be an underlying reason for the malaria outbreaks in Yala. Objectives: In this study, we aimed to assess the malaria knowledge, prevention practices, and insecticidetreated net (ITN) ownership and use among migrants in four malaria transmission districts of Yala Province. Methods: We conducted a cross-sectional survey with two-stage cluster sampling recruiting 414 migrants. We identified migrants’ locations with the help of key informants. Migrants aged 18 years and older were interviewed …

Characteristics Of Habitat, Distribution, And Diversity Of Anopheles Spp In Kemelak Bindung Langit Village, Ogan Komering Ulu Regency, South Sumatra, Giri Maretasari, Yuanita Windusari, Syafrina Lamin, Laila Hanum, Dwi Septiawati

Journal of Environmental Science and Sustainable Development

Malaria is an infectious disease caused by Plasmodium andis transmitted through the bite of a female Anopheles vector. Ogan Komering Ulu (OKU) is a district in South Sumatra that is endemic to malaria. The study aims to determine habitat type, environmental factors that influence larvae development, and distribution of Anopheles larvae. The experiment was conducted from January to February 2019 in the Kelurahan Kemelak Bindung Langit, OKU. Species identification was carried out in the Entomology Laboratory, Baturaja Health Research and Development Center, OKU. Sampling locations were determined based on field observations, through simple purposive sampling. Identification of mosquito larvae which …

Preparation And Standardisation Of Plasmodium Falciparum Nosode, Rajesh Shah

Indian Journal of Research in Homoeopathy

Background: Malaria officinalis, a Homoeopathic preparation used against malaria, was prepared from decomposed vegetable matter from a marshy area by G. W. Bowen in 1862. No scientific published material is available on the source of any malaria-related nosode. There is a need to develop the new nosode using the organisms. The author has developed the nosode from Plasmodium falciparum parasites, and the detailed method of preparation is described in this manuscript. Objective: Preparation and standardisation of Homoeopathic nosode prepared from P. falciparum parasites, which could be explored for further research and therapeutic efficacy. Materials and Methods: The most widely cultivated …

Infection Of Plasmodium Knowlesi Malaria In Human, I Gede Yasa Asmara

Jurnal Penyakit Dalam Indonesia

Plasmodium knowlesi (P. knowlesi) has been recognised as the fifth of malaria infections in human after P. vivax, P. falciparum, P. malariae and P. ovale. Epidemiology and clinical features of the disease have much been discussed only in several literatures since the incidence increased in Kapit Division, Sarawak, Malaysia in 2004. A large-scale research investigating real incidence of the infection in South East Asia is important. Because of rapid life cycle, the number of parasite in the blood can increase significantly, result in potential severe malaria. Pathophysiology aspect of the disease has not been clear yet, particularly on how severe …

The Battle Against Malaria: A Teachable Moment, Randy K. Schwartz

Journal of Humanistic Mathematics

Malaria has been humanity’s worst public health problem throughout recorded history. Mathematical methods are needed to understand which factors are relevant to the disease and to develop counter-measures against it. This article and the accompanying exercises provide examples of those methods for use in lower- or upper-level courses dealing with probability, statistics, or population modeling. These can be used to illustrate such concepts as correlation, causation, conditional probability, and independence. The article explains how the apparent link between sickle cell trait and resistance to malaria was first verified in Uganda using the chi-squared probability distribution. It goes on to explain …

An Investigation On The Prevalence And Efficiency Of Immunochromatographic Testing In Suspected Malarial Patients Of Rawalpindi And Islamabad, Pakistan, Saima Jabeen, Sobia Kanwal, Mazhar Qayyum, Umair Farrukh, Shahzad Abdul Hameed

Turkish Journal of Medical Sciences

Background/aim: The prevalences of Plasmodium falciparum and Plasmodium vivax are increasing rapidly in Pakistan, but recent data on the epidemiology of malaria are not properly reported with scarce diagnostic methods for quick diagnosis. This study was designed to determine the current prevalence and distribution of Plasmodium species in the vicinity of Rawalpindi and Islamabad and report on the validity of the immunochromatographic test (ICT) in diagnosing malarial infections. Materials and methods: A total of 1500 blood samples obtained from a local hospital were screened during the course of this study via microscopic examination and ICT. Results: It was seen that …

Evaluation Of New Multiplex Pcr Primers For The Identification Ofplasmodium Species Found In Sabah, Malaysia, Cheronie Shely Stanis, Beng Kah Song, Tock Hing Chua, Yee Ling Lau, Jenarun Jelip

Turkish Journal of Medical Sciences

Background/aim: Malaria is a major public health problem, especially in the Southeast Asia region, caused by 5 species of Plasmodium (P. falciparum, P. vivax, P. malariae, P. ovale, and P. knowlesi). The aim of this study was to compare parasite species identification methods using the new multiplex polymerase chain reaction (PCR) against nested PCR and microscopy. Materials and methods: Blood samples on filter papers were subject to conventional PCR methods using primers designed by us in multiplex PCR and previously designed primers of nested PCR. Both sets of results were compared with microscopic identification. Results: Of the 129 samples identified …

Genotyping Of Plasmodium Falciparum By Allele-Specificamplification Of The Merozoite Surface Protein-1 Locus, W Aichanapun, S Seethamchai, T Tia, C. Putaporntip

Chulalongkorn Medical Journal

Problem/background : Allele-specific amplification is an important tool for a largescale study of geographic distribution of pathogens harboringpolymorphic genes. In this study, we have developed a simplemethod to differentiate strains of Plasmodium falciparum basedon polymorphic block 2 located at the 5’ portion of the merozoitesurface protein-1 gene (PfMsp-1). Block 2 of PfMsp-1, a strongcandidate for asexual blood-stage vaccine, contains 3 basicsequence types with MAD20 type, K1 type and RO33 type asrepresentative alleles.Objective : To develop a polymerase chain reaction (PCR) method capableof detecting PfMsp-1 genotypes.Design : Experimental study.Setting : Department of Parasitology, Faculty of Medicine, ChulalongkornUniversity.Materials and Methods : The …

Identifikasi Vektor Malaria, Solikhah Solikhah

Kesmas

Kabupaten Kulonprogo merupakan salah satu daerah endemis malaria di Daerah Istimewa Yogyakarta dan Jawa Tengah. Lonjakan jumlah kasus malaria terjadi hampir dua kali lipat sejak tahun 2010 hingga bulan Agustus 2011. Penelitian ini bertujuan untuk mengetahui jenis Plasmodium pada penyakit malaria. Penelitian eksplorasi ini menggunakan desain studi cross sectional. Diagnosis kasus malaria diperiksa menggunakan pemeriksaan darah tebal secara mikroskopis dan untuk mengetahui faktor sosiodemografi dilakukan wawancara menggunakan kuesioner. Populasi studi adalah penduduk di wilayah Kabupaten Kulonprogo yang diambil secara proporsional pada bulan Januari sampai bulan Juni 2012. Data dianalisis secara univariat dalam bentuk grafik dan tabulasi. Hasil penelitian ini adalah …

Persepsi, Peluang Aksi, Dan Infomasi Serta Perilaku Pencegahan Malaria, Elviera Gamelia, Siwi Pramatama Mars Wijayanti

Kesmas

Di dunia, malaria masih menjadi masalah kesehatan masyarakat terutama di negara-negara tropis termasuk Indonesia. Di Jawa Tengah, kasus malaria terus memperlihatkan kecenderungan yang meningkat, salah satu daerah endemis malaria di Banyumas adalah Puskesmas II Sumpiuh. Berdasarkan survei pendahuluan masih banyak ditemukan perilaku berisiko yang dapat mengakibatkan terjadi malaria. Penelitian ini bertujuan mengetahui persepsi masyarakat, kemungkinan aksi, dan informasi tentang malaria yang berpengaruh terhadap perilaku pencegahan malaria di Puskesmas Sumpiuh II Banyumas. Penelitian observasional dengan pendekatan cross sectional ini dilakukan pada populasi kepala keluarga di Puskesmas II Sumpiuh. Jumlah sampel sebanyak 95 kepala keluarga ditarik menggunakan metode simple random sampling. Pengumpulan …

Faktor Lingkungan Dan Perilaku Masyarakat Tentang Malaria Di Kecamatan Kupang Timur Kabupaten Kupang, Karolus Ngambut, Oktafianus Sila

Kesmas

Penelitian ini bertujuan untuk menggambarkan faktor lingkungan dan perilaku masyarakat tentang malaria di Kecamatan Kupang Timur Kabupaten Kupang. Dengan desain studi potong lintang, populasi penelitian adalah seluruh rumah tangga di Kecamatan Kupang Timur dengan metode simple random sampling dan diperoleh 185 rumah tangga yang dijadikan sampel. Hasil penelitian menunjukkan prevalens malaria klinis adalah 108 (14,4%) pada satu tahun terakhir. Gambaran faktor lingkungan rumah penderita malaria yaitu dinding rumah terbuat dari bebak dan papan masing-masing 43,6% dan 7,9%. Selain itu, atap rumah terbuat dari alang-alang atau daun lontar (21,1%). Sementara letak rumah dekat dengan breding places nyamuk anopheles, yaitu sawah dan …

Perbandingan Rapid Diagnostic Test Dan Pemeriksaan Mikroskopik Pada Diagnosis Malaria, Lombok Siahaan

Kesmas

Penelitian ini dilakukan untuk membandingkan penggunaan Rapid diagnostic test dengan pemeriksaan mikroskopik (apusan darah) dalam menegakkan diagnosis malaria. Penelitian uji diagnostik ini dilakukan di Kabupaten Nias Selatan dan Kotamadya Sabang, Sumatera Utara. Apusan darah diwarnai dengan larutan Giemsa 10% dan dibaca oleh pemeriksa yang sudah terlatih. Rapid diagnostic test dilakukan dengan menggunakan parascreen. Uji diagnostik rapid diagnostic test secara umum diperoleh hasil yaitu sensitivitas 63,8%; spesifisitas 100%; Positive Predictive Value (PPV) 100%; dan negative predictive value (NPV) 93,5%. Kepadatan parasit pada rapid diagnostic test (+) dan mikroskopik (+) adalah 1.483 ± 583 parasit/μl. Sementara, kepadatan parasit pada pemeriksaan rapid diagnostic …

Faktor Dominan Yang Mempengaruhi Kejadian Malaria Di Perdesaan, Dewi Susanna, Tris Eryando

Kesmas

KLB malaria selama periode 1998-2003 telah menyerang 15 propinsi yang meliputi 84 desa endemis dengan jumlah penderita 27.000 dengan kematian 368. Hewan besar seperti sapi, kerbau dan kuda adalah merupakan cattle barrier malaria. Hewan tersebut perlu diteliti agar dapat diketahui jenis hewan dan tempat hidup hewan (kandang) terhadap kejadian malaria. Tujuan umum penelitian ini adalah untuk mengetahui faktor dominan yang mempengaruhi kejadian malaria di pedesaan. Jenis penelitian adalah non-intervensi, merupakan analisis lanjut data sekunder yaitu “Riset Kesehatan Dasar 2007”. Subyek yang dianalisis sebanyak 618.593 yang bertempat tinggal di perdesaan. Analisis dilakukan dengan metoda multivariat menggunakan regresi logistik. Ternak dibagi menjadi …

Situasi Malaria Di Kabupaten Lebak, Fauzul Hayat, Nia Kurniatillah

Kesmas

Pada periode 2002-2006, di Kabupaten Lebak, API tergolong Middle Case Incidence (MCI), dengan nilai rata-rata (2.87%) dan berada pada kisaran 2.04-4.51%. Dari 35 wilayah kerja puskesmas terdapat enam wilayah endemis yang meliputi puskesmas Malimping, Binuangeun, Bayah, Cihara, Panggarangan dan Cilograng. Ada wilayah kerja puskesmas yang dilaporkan dengan klasifikasi MCI. Penderita positif malaria cenderung meningkat secara fluktuatif dengan puncak yang tidak jelas, kasus positif malaria tertingi ditemukan pada bulan Februari, Maret, Mei, Juli dan Desember. Tingkat infeksi malaria yang tinggi pada kelompok populasi ditentukan berdasarkan proporsi sediaan darah positif malaria dari sediaan darah yang diperiksa dengan angka SPR 006 rata-rata 12.64%, …

Kehamilan Dan Kejadian Malaria Di Puskesmas Way Muli, Lampung Selatan, Ismen Ismen

Kesmas

Kelompok yang paling rentan terhadap malaria adalah wanita hamil dengan berbagai akibat terhadap ibu dan janin yang dikandungnya. Di Indonesia, penelit- ian tentang hubungan kehamilan dengan kejadian malaria masih sangat jarang dilakukan. Tujuan penelitian ini adalah mengetahui hubungan antara kehamilan dengan kejadian malaria. Penelitian ini menggunakan desain studi kasus control dengan sumber data proner di populasi di wilayah kerja Puskesmas Way Muli Kecamatan Rajabasa, Kabupaten Lampung Selatan, Provinsi Lampung. Populasi studi adalah wanita usia 15 – 49 tahun yang datang pada saat penelit- ian pada periode November sampai dengan Desember 2006. Pengumpulan data dengan cara wawancara dan pengambilan sediaan darah. …

Correlation Of In Vivo And In Vitro Responses Ofplasmodium Vivax To Chloroquine, K. Congpuong, K. Na Bangchang, O. Tasanor, J. Sirichaisinthop, Wh. Wernsdorfer

Chulalongkorn Medical Journal

No abstract provided.

Formal Saline Protocol As An Alternative Fixationin Routine Cytological Preparation, K. Keetacheeva, D. Sachakaew, P. Sampatanukul

Chulalongkorn Medical Journal

No abstract provided.

Mitochondrial Function Of Human Malarial Parasiteplasmodium Falciparum Cultivated In Vitro :Implications For Antimalarial Drug Design, Jerapan Krungkrai, Preecha Leangaramkul, Rachanok Kanjanarithisak, Sudaratana R. Krungkrai

Chulalongkorn Medical Journal

No abstract provided.

Biochemistry Of Malaria Ii : Metabolism Of Nucleic Acids, Jerapan Krunglcrai

Chulalongkorn Medical Journal

No abstract provided.