Medicine and Health Sciences Commons^™

Management Of Macrovascular Diabetic Complications: A Single-Center Case Series Analysis Of Consecutively Attending Patients In Primary Care, Sanda Maria Crețoiu, Mihaela Adela Iancu, Laura Maria Condur, Teodor Salmen, Andreea Steriu, Ana Maria Alexandra Stănescu, Irina Anca Eremia, Cristina Mihaela Olariu, Eliza Elena Cinteză, Camelia Cristina Diaconu

Journal of Mind and Medical Sciences

Introduction. The prevalence of diabetes mellitus is increasing, with type 2 diabetes (T2DM) being a major health priority for any public health system. Increased arterial stiffness in patients with diabetes will lead to the appearance of vascular complications. Increased arterial stiffness in patients with diabetes usually leads to vascular complications. Any earlier diagnosis of impaired macrovascular evidence may lead to improved outcomes in patient care. The objective of our study was to assess and evaluate the finger-toe pulse wave velocity (ftPWV), as a measure of arterial stiffness, in order to assist with early detection of macrovascular diabetic complications. Materials and …

Acute Bilateral Pyelonephritis In The Setting Of Newly Diagnosed Diabetes Mellitus: A Case Report, Jessenia Ariana Contreras, Satwinder Singh, Ramesh Alwarappan

HCA Healthcare Journal of Medicine

Introduction

Acute pyelonephritis is a bacterial infection that starts in the bladder and ascends to the kidneys, causing inflammation of the renal parenchyma. Women are more likely to get infected compared to men, with diabetics being at higher risk. The pathophysiology of how diabetics are more prone to getting urinary tract infections/pyelonephritis has been studied, particularly the difference between bilateral pyelonephritis and unilateral pyelonephritis.

Case Presentation

This case presentation follows a 51-year-old Spanish-speaking woman with a past medical history of prediabetes, bilateral tubal ligation, and perimenopause. She presented to the hospital for abdominal and back pain, fevers, and weakness that …

Mangosteen Peel Extract Vs Tetracycline Gel In Treatment Of Periodontal Abscess In Type-2 Diabetes – A Randomized Clinical Trial, Ksv Ramesh, Itha Joshna, Gautami S. Penmetsa, Gottumukkala Nvs Sruthima, Pasupuleti Mohan Kumar, Boddeda Anusha, Sathya Valli

Journal of Dentistry Indonesia

Herbal products are gaining popularity due to their diverse biological action and safety. Mangosteen peel extract has antibacterial and anti-inflammatory properties and can be used to treat periodontal diseases. Objective: To compare the efficacy of mangosteen peel extract and tetracycline gel as an adjunct to non-surgical management of periodontal abscess in type-II diabetes patients. Methods: This was a double blinded, randomized clinical trial included 20 Patients with Type-II diabetes. Both test and control groups received NSPT followed by adjunctive local application of mangosteen peel extract and tetracycline gel. Clinical parameters i.e., Probing depth (PPD), Clinical attachment level (CAL), …

Public Health Insurance: An Approach To Mitigate The Burden Of Diabetes In Low Resource Settings, Jideuma I. Egwim, Namgyal Kyulo, Hadi Danawi, Aaron B. Mendelsohn

Journal of Social, Behavioral, and Health Sciences

Background: Diabetes mellitus is a significant public health concern globally as well as in Owerri, Nigeria. The deleterious effects of diabetes have been linked to poor glycemic control. According to the International Diabetes Federation, poor glycemic control is reflected in glycosylated hemoglobin levels greater than 7.0%, which are associated with substantial morbidity and mortality. Studies have shown a dramatic rise in diabetic complications in Nigeria, particularly in Owerri. However, evidence is lacking on specific risk factors associated with poor glycemic control among diabetes mellitus patients in Owerri. There is a gap in the literature regarding the association between health insurance …

Investigation Of The Dmft Index Of Type 2 Diabetes Mellitus Patients With A 5-Year Interval Cross Sectional Study, Oğuzhan Altun, Numan Dedeoğlu, Duygu Çelik Özen, Edanur Topaloğlu, Begüm Özemre

Future Dental Journal

Aim: Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease with insulin deficiency or dysfunction. Notably, T2DM also has clinical and radiological implications in the oral region. This study aims to evaluate the changes in decay, missed, and filled teeth (DMFT) indexes on panoramic radiographs of T2DM patients at the end of a five-year follow-up and compare them with the control group.

Materials and Methods: Two panoramic radiographs taken five years (mean 5.32±0.24) apart from each of the 92 patients (46 T2DM and 46 healthy) were evaluated. The DMFT index was calculated in a total of 184 panoramic …

Prevalence And Risk Factors Of Post-Partum Infections At Family Health Facilities In North Sinai, Egypt, Aml Ahmed Salama, Samah Abduallah Salim, Safa Hamdy Alkalash

Menoufia Medical Journal

Objectives: To assess the prevalence of different types of postpartum infections and their risk factors among women attending family health facilities in Bir El-Abd district, North Sinai, Egypt. Background: The postpartum period is an imminent period among women; infection in this critical period is a preventable cause of maternal morbidity and mortality. Methods: An analytical cross-sectional study was conducted among a random sample of 220 women attending primary health facilities in Bir El-Abd district, North Sinai, during their postpartum period. They were assessed through a complete history taken via a pre-designed questionnaire. Complete general and local examinations were done through …

Adjunctive Use Of Laser Biostimulation With Nonsurgical Periodontal Therapy: A Split Mouth, Randomized, Case-Control Study In Diabetic And Nondiabetic Periodontitispatients, Funda Akansel, Umur Sakallioğlu, Müge Lütfi̇oğlu, Feyza Otan Özden, Adil Karadağ

Turkish Journal of Medical Sciences

Laser biostimulation therapy (LBT) is suggested to have positive effects on periodontal healing. This study evaluatedLBT with nonsurgical periodontal therapy (NSPT) in diabetes mellitus (DM) and systemic health (SH) conditions.Materials and methods: Thirty periodontitis patients (15 with DM and 15 with SH) were included in the study, which had a split-mouthdesign, by applying LBT in the mouth of the same systemic condition. Thus, 4 study groups were formed, as 1) NSPT – DM: NSPT alonein DM, 2) NSPT + LBT – DM: NSPT + LBT application in DM, 3) NSPT – SH: NSPT alone in SH, and 4) NSPT + …

Role Of Inflammatory And Growth Factors In Diabetes Mellitus, Sayed Mohammed Firdous, Sourav Pal

Palestinian Medical and Pharmaceutical Journal

In diabetes mellitus, both inflammatory and growth factors play significant roles in the development and progression of the disease and its associated complications. Diabetics frequently show signs of chronic, low-grade inflammation. Insulin resistance and beta-cell dysfunction are exacerbated by the high levels of pro-inflammatory cytokines prevalent in diabetes, such as TNF-α and IL-6. High levels of the inflammatory marker C-reactive protein are linked to insulin resistance and an increased risk of cardiovascular disease. An upsurge in in diabetes is caused by NF-κB activation. Complications and pathological processes in diabetes may be exacerbated by a dysregulation of growth factors. The angiogenesis-related …

Contraceptive Methods In Diabetic Women Referring To Government Diabetes Clinics In Northern Iran, Roya Mansour-Ghanaei, Yalda Donyaei-Mobarrez, Kobra Abouzari-Gazafroodi

Makara Journal of Health Research

Background: Unwanted pregnancies in diabetic women can endanger the mother and the fetus. The present study was conducted to determine contraceptive methods for diabetic women referred to government diabetes clinics in the north of Iran.

Methods: A total of 153 diabetic women referred to government clinics in Guilan were included in this cross-sectional study. A questionnaire made by the researcher regarding personal and social information and information related to contraceptive methods was administered. Data were analyzed analytically using SPSS version 19.

Results: The findings of the present study revealed that 87.6% of diabetic women used contraceptive methods, …

Comprehensive Comparison Of Clinicoradiological, Laboratory, And Prognostic Factors Of Community-Acquired Pneumonia In Diabetic And Nondiabetic Hospitalized Patients, Seyyed Hamid Hashemi, Fatemeh Saki, Shiva Borzouei, Rashed Bawand, Alireza Soltanian

Turkish Journal of Medical Sciences

Background/aim: Community-acquired pneumonia (CAP) is one of the leading infectious causes of mortality, and diabetes mellitus is a globally prevalent disease. Consequently, the cooccurrence of these two disorders can be common and create challenging medical conditions. Therefore, it was aimed to compare the various aspects of CAP in diabetic and nondiabetic patients, in order to have a comprehensive and comparative picture of the differences. Materials and methods: In this cross-sectional study, CAP patients with and without diabetes were assessed for clinicoradiological signs, laboratory features, disease severity, and pneumonia outcomes. Results: Analyzed herein were 172 CAP patients (77 had diabetes and …

Protective Effects Of Swimming Exercises And Metformin On Cardiac And Aortic Damage Caused By A High-Fat Diet In Obese Rats With Type 2 Diabetes, By Regulating The Bcl2/Bax Signaling Pathway, Ebru Özüdoğru, Emrah Atay, Mehtap Savran, Hali̇l Aşci, Özlem Özmen, Şenay Topsakal

Turkish Journal of Medical Sciences

Background/aim: Due to the increasing mortality and morbidity rates in diabetes mellitus (DM), which is one of the biggest health problems of our age, many treatment modalities are still being tried. The positive effects of metformin (MET) and physical exercise (EXE) on the pathophysiology of diabetes are well known. In this study, it was aimed to detail these positive effects of MET and EXE in combination on the basis of inflammation, apoptosis mechanisms, and endogen nesfatin-1 (NES-1) synthesis. Materials and methods: Twenty-seven type 2 DM (DM-2) male Wistar Albino rats were divided into 4 groups, as the high-fat diet (HFD), …

Diabetes Mellitus: Interdisciplinary Medical, Surgical And Psychological Therapeutic Approach, Bogdan Socea, Adrian Silaghi, Laura Florentina Rebegea, Daniela Gabriela Balan, Cristian Balalau, Tiberiu Ștefăniță Tenea-Cojan, Doina Andrada Mihai, Ioana Paunica

Journal of Mind and Medical Sciences

Diabetes mellitus is a complex and widespread metabolic disease, having extremely complex implications (biological, psychological, social) for patients. Understanding the pathophysiology of diabetes (majorly influenced by various factors such as genetic predisposition, age, lifestyle choices, etc.) is essential for the prevention of this condition and the establishment of effective treatment strategies. The latest and relevant literature data related to the epidemiology, pathophysiology, and treatment of diabetes are presented, after an exhaustive review of the articles published on this topic and indexed in the WOS, PubMed, Scopus and Google Scholar databases. Preventing or delaying the onset of diabetes can be achieved …

Evaluation Of Chronic Pruritus And Associated Skin Findings In Patients With Diabetes Mellitus, Fatma Avci Merdi̇n, Ahmet Taha Aydemi̇r, Fatma Nur Korkmaz, Fatma Tuğçe Şah Ünal, Asena Gökçay Canpolat, Ayşe Öktem, Özgür Demi̇r, Mustafa Şahi̇n, Rifat Emral, Murat Fai̇k Erdoğan, Sevi̇m Güllü, Aydin Vedi̇a Gedi̇k, Peli̇n Koçyi̇ği̇t, Demet Çorapçioğlu

Turkish Journal of Medical Sciences

Background/aim: To explore the dermatological lesions associated with chronic pruritus in patients who were followed up at our clinic for type 1 and type 2 diabetes mellitus (DM). Materials and methods: The study population consisted of 249 patients with DM, who presented to the endocrinology clinic at Ankara University Faculty of Medicine between January 2022, and March 2022, regardless of whether they had reported experiencing pruritus symptoms. The visual analog scale and 5-D itch scale were used to determine the severity of itching in patients. Dermatological examination findings were also evaluated. Results: Of the 249 patients with DM, mean duration …

Profil Pasien Ketoasidosis Diabetikum Di Rumah Sakit Rujukan Tersier Di Bali, Indonesia, Noviana Joenputri Nj, Ketut Suastika Ks, Wira Gotera Wg, Made Ratna Saraswati Mrs, I Made Pande Dwipayana Impd, I Made Siswadi Semadi Imss, Ida Bagus Aditya Nugraha Iban

Jurnal Penyakit Dalam Indonesia

Introduction. Diabetic ketoacidosis (DKA) is one of life-threatening acute complication of diabetes mellitus (DM) characterized by hyperglycemia, ketosis, and acidosis. The prevalence of DM is increasing, therefore the incidence of DKA is predicted to continue to increase. The aim of this study was to obtain the profile of DKA patients in RSUP Prof. Dr. IGNG. Ngoerah (RSPN), Denpasar, Bali as a tertiary refferal hospital of Bali and Nusa Tenggara region.

Methods. This study was a cohort retrospective study. All patients aged 18 years or older with a diagnosis of DKA during Januari 2022 to February 2023 at RSPN, …

Patient And Provider Experience With Artificial Intelligence Screening Technology For Diabetic Retinopathy In A Rural Primary Care Setting, Brian M. Nolan, Emma R. Daybranch, Kerri Barton, Neil Korsen

Journal of Maine Medical Center

Introduction: The development of autonomous artificial intelligence for interpreting diabetic retinopathy (DR) images has allowed for point-of-care testing in the primary care setting. This study describes patient and provider experiences and perceptions of the artificial intelligence DR screening technology called EyeArt by EyeNuk during implementation of the tool at Western Maine Primary Care in Norway, Maine.

Methods: This non-randomized, single-center, prospective observational study surveyed 102 patients and 13 primary care providers on their experience of the new screening intervention.

Results: All surveyed providers agreed that the new screening tool would improve access and annual screening rates. Some providers also identified …

Postprandial And Fasting Lipopolysaccharide Levels In Healthy Hispanic Residents Of Southeast Texas With Positive Family History Of Type 2 Diabetes, Amanda J. Wheeler, Yu Lun Tai, Smaran Marupudi, Ryan D. Russell

International Journal of Exercise Science: Conference Proceedings

PURPOSE: Healthy people with a family history (FH+) of type 2 diabetes (T2D) display impaired metabolic and microvascular function prior to glucose intolerance, and are at greater risk for developing T2D. While mechanisms to explain this disparity are lacking, it is possible that intestinal permeability plays a role, as it is also linked with insulin resistance, glucose intolerance, and chronic inflammation. Lipopolysaccharides (LPS) act as an outer membrane component of gram-negative bacteria in intestines and play a role in inflammation and chronic disease when in circulation, thus serving as a surrogate measure of intestinal permeability. However, the link between FH+ …

Impact Of Diabetes Mellitus In Arteriovenous Fistula Dysfunction In Patients On Regular Hemodialysis, Emad Allam Mohamed, Mohamed Ahmed Elsayed, Mohamed Abo Elnaga Mohamed, Mohamed Amer Farok Amin

Al-Azhar International Medical Journal

Background: Primary arteriovenous fistula (AVF) failure has been linked to the existence of diabetes mellitus in some individuals, but not in all. Aim of the work: The study's objective is to assess how Diabetes Mellitus affects individuals receiving regular hemodialysis (HD) who have AVF malfunction. Patient and methods: All of the 90 participants in this research had end-stage renal disease (ESRD) and were being treated with regular HD. The subjects were separated into three groups according on age and sex; Group A had Twenty (20) non-diabetic patients enrolled as control group without any diagnosis of liver disease, Group B had …

Characteristics Of Diabetes Mellitus Patients In Turkey: An Analysis Of National Electronic Health Records, Mustafa Mahi̇r Ülgü, Kemal Hakan Gülkesen, Abdullah Akünal, Mustafa Okan Ayvali, Neşe Zayi̇m, Şuayip Bi̇ri̇nci̇, Mustafa Kemal Balci

Turkish Journal of Medical Sciences

Background/aim: It was estimated that there were 537 million people with diabetes mellitus in 2021, representing 10.5% of the global adult population. Diabetes prevalence in Turkey is 13.5%, according to a meta-analysis and 17.3% according to a recent study. Although the primary purpose of Electronic Health Records (EHRs) is clinical, researchers can use them to conduct epidemiologic investigations. This study aims to document the prevalence of diabetes and to evaluate the healthcare utilization of people with diabetes compared to the people without diabetes, based on national EHR. Methods: Only people over 14 years old were included in the analysis. Our …

Factors Associated With Depression Among Type 2 Diabetes Mellitus Patients At A Tertiary Hospital During The Covid-19 Pandemic, Muhammad Ikhsan Mokoagow, Dian Pitawati, Ditya Nona Arisandy, Nadya Magfira, Pratiwi Indah Palupi, Jerry Nasarudin, Marina Epriliawati, Ida Ayu Kshanti

Kesmas

Diabetes mellitus is a metabolic disorder characterized by chronic hyperglycemia that can cause various complications, economic burdens, and psychosocial issues that eventually lead to depression. This study aimed to describe the prevalence of depression among type 2 diabetes mellitus patients in the Internal Medicine Outpatient Clinic of a South Jakarta tertiary hospital during the COVID-19 pandemic. This cross-sectional study was conducted from May to July 2021. The data were collected consecutively from 100 patients aged 18 years or older who came for regular consultation. The instrument used for determining depression is Beck Depression Inventory-II. The prevalence of depression, a correlation …

Cognitive Function In Type 2 Diabetes Mellitus Patients Taking Metformin And Metformin-Sulfonylurea, Abu Rachman, Rani Sauriasari, Nadia Farhanah Syafhan, Pukovisa Prawiroharjo, Hindun Wilda Risni

Kesmas

The most prescribed antidiabetic drugs in Indonesian primary health care are metformin or a combination of metformin and sulfonylurea. Studies on metformin have shown various impacts on cognitive decline in patients with type 2 diabetes mellitus, whereas sulfonylurea has been shown to reduce this impact. This study aimed to compare the impacts of metformin and metformin-sulfonylurea on cognitive function and determine what factors affected it. This cross-sectional study was conducted at Pasar Minggu Primary Health Care involving 142 type 2 diabetes mellitus patients taking metformin or metformin-sulfonylurea for > 6 months and aged > 36 years. Cognitive function was assessed using the …

Prognostic Value Of Coronary Computed Tomography Angiography In Asymptomatic Diabetic Patients, Abdalla Mostafa, Ahmed Abdalla, Ahmed Gaafar, Mahmoud Z. Attia, Waleed Abdou

Menoufia Medical Journal

Objectives To study the prognostic value of coronary computed tomography (CT) angiography in asymptomatic diabetic patients. Background Diabetic patients have a higher prevalence of coronary artery disease (CAD) and are more likely to have silent myocardial ischemia and myocardial infarction than nondiabetics and are characterized by multivessel disease and calcified, diffuse, and distal lesions. CT coronary angiography is a safe, accurate, and reliable technique of high ability to detect CAD and estimate the degree of obstruction, number of affected arteries, and the pattern of their affection and a reliable modality for exclusion of CAD. Patients and methods This study was …

Long Noncoding Rna As A Diagnostic Tool In Vascular Complication Of Diabetes, Mohamed El Sayed Sakr, Nabil A. El Kafrawy, Shaimaa K. Zewain, Shimaa A. Refaat, Shimaa A. Hassanein

Menoufia Medical Journal

Background At present, there is really no unique biomarker for detecting diabetes-related vascular complications. As a result, it is critical to investigate specific biomarkers for diagnosing, detecting, and catching the early stages of disease progression. Objectives To analyze the relationship of long noncoding RNA in patients with asymptomatic atherosclerotic diabetic. Patients and methods This case–control study included 312 participants recruited from Menoufia University Hospitals' Internal Medicine Outpatient Clinics and Inpatient Departments and divided into two groups: group I was the diabetic with subclinical atherosclerosis group, which included 176 patients with type 2 diabetes mellitus, with the carotid intima-media thickness assessed …

Fat Mass And Obesity-Associated Gene Polymorphisms Rs9939609 And Rs17817449 In Type 2 Diabetic Egyptians, Gehan K. El Saeed, Marwa M. Omar, Shaza E. Ahmed, Thoria A. Omar, Walid A. Shehab-Eldin

Menoufia Medical Journal

Background Individual predisposition to obesity and type 2 diabetes mellitus (T2DM) is determined by the interaction between genetic and environmental factors. The fat mass and obesity-associated gene (FTO) is an obesity-susceptibility gene identified to have a huge effect on obesity and DM in different populations. Objectives To investigate the association between FTO gene polymorphisms rs9939609 and rs17817449 and prediction of T2DM in Egyptian obese patients. Patients and methods In this case–control study, PCR–restriction fragment length polymorphism was used for investigating allele and genotype frequencies of FTO rs9939609 and rs17817449 in 90 participants divided into two groups: diabetic group …

Indicators Of Cardiac Autonomic Dysfunction Associated With Chronic Hyperglycemia: Implications On Vascular Surrogates And Heart Failure, Yap-Hang Chan, Bernard Man-Yung Cheung, Hung-Fat Tse

Journal of the Hong Kong College of Cardiology

Background: Limited data exist on the role of chronic hyperglycemia-related cardiac autonomic dysfunction in incident heart failure (HF). We investigated the relations of resting heart rate (HR) and PR interval with chronic hyperglycemia, and effects on new-onset HF.

Methods: We prospectively studied 550 patients with prior coronary disease, ischemic stroke and/ or type 2 diabetes. Incident HF was ascertained. Heart rate-PR interval dissociation was defined as counter-physiological co-occurrence of increased PR interval (>mean; 173.3ms) and increased resting HR (>mean; 64.4 beats/min).

Results: Over 63 ±11 months, 6.7% patients developed new-onset HF. Resting HR³75bpm was independently predictive of new-onset …

The Association Between Adherence To Oral Antihyperglycemic Agent And Hba1c Level, Indana Ayu Soraya, Rani Sauriasari, Pukovisa Prawiroharjo, Hindun Wilda Risni

Pharmaceutical Sciences and Research

Adherence to taking medication is essential for patients with chronic diseases such as Type 2 Diabetes Mellitus (T2DM). There have been many studies about the association between medication adherence and HbA1c levels, but few have used Adherence Refills and Medications Scale (ARMS) questionnaire and Proportion of Days Covered (PDC) method to measure adherence in Indonesian population. The aim of this study were to assess the association of medication adherence to HbA1c levels and compare two methods of adherence measurements. This research was conducted at Pasar Minggu Public Health Center, Jakarta using a cross-sectional design. The adherence assessment was conducted using …

An Overlooked Problem: A Qualitative Meta-Synthesis From Experience Of Men With Diabetic Erectile Dysfunction, Junjira Seesawang, Pulawit Thongtaeng

Journal of Health Research

Background: ED is negatively associated with men’s sexual function capacity, emotional, intimate relationship and particularly psychological well-being. The purpose of this study was to synthesize qualitative findings which explain the experiences of men with diabetes who have erectile dysfunction.

Method: A meta-synthesis was performed. A search for qualitative studies published in English from 2010 to 2020 was conducted using PubMed, CINAHL, PsycInfo, and Science Direct databases. The main key words included: experience, men/male patient, erectile dysfunction, diabetes, diabetic erectile dysfunction, and qualitative research. Inductive and interpretative technique was used to analyze and synthesize findings from qualitative studies and reviewed by …

Assessment Of Retinal Ganglion-Cell Complex Using Spectral-Domain Optical Coherence Tomography In Diabetic Patients Without Retinopathy, Asmaa M. Ibrahim, Mustafa K. Nassar, Shaimaa S. Helal

Menoufia Medical Journal

Background Diabetic retinopathy (DR) consists of microvascular changes, although recent investigations have demonstrated that neurodegeneration may occur earlier. Objectives To assess ganglion-cell complex thickness using spectral-domain optical coherence tomography in diabetic patients without retinopathy. Patients and methods This was a cross-sectional case–control study conducted at Shebin El kom Ophthalmology Hospital and Tiba Ophthalmological Center on 200 patients divided into two groups: group A involves 100 diabetic patients without DR. Group B involves 100 healthy controls. All participants underwent full ophthalmological and medical history, ophthalmological examination with measurement of the macular ganglion-cell layer–inner-plexiform layer (GCL–IPL) thickness, and retinal nerve-fiber-layer (RNFL) thickness …

Correlation Of Anterior Ocular-Segment Biometry With Glycated Hemoglobin Level In Type-2 Diabetic Patients, Gehan A. A. Elsabrout, Hatem M. G. Marey, Marwa A. Zaky

Menoufia Medical Journal

Background Diabetic retinopathy (DR), nephropathy, and peripheral neuropathy are the common complications of diabetes mellitus. DR is one of the causes of blindness worldwide. Although diabetic-eye disease is often thought to refer merely to the retina, the anterior segment of the eye has also been shown to be affected in diabetes. Objective To compare the anterior ocular-segment biometry among type-2 diabetes mellitus with no DR, nonproliferative diabetic retinopathy (NPDR), and evaluate the correlation of anterior ocular-segment biometry with glycosylated hemoglobin (HbA1c) level. Patients and methods A cross-sectional study was conducted on 48 patients. The patients were randomly selected from the …

Macular Thickness Assessment In Diabetic Patients Without Retinopathy, Adel G. Zaky, Amin F. Ellakwa, Asmaa A. Askria, Moatz F. Elsawy, Saber H. El Sayed

Menoufia Medical Journal

Objective A comparative study of macular thickness measurements with optical coherence tomography (OCT) in patients with diabetes mellitus without diabetic retinopathy (DR) versus healthy controls. Background DR is one of the most common causes of deterioration of vision in the adult population. Recently, some studies showed that the degeneration of the retinal neuronal cells starts before the microvascular changes appear clinically. Patients and methods Sixty-five patients with diabetes mellitus (without DR underwent full ophthalmic examination; colored fundus photography, fluorescin fundus angiography, and OCT. Mean macular thickness measured by OCT was calculated for the central fovea, the perifoveal, and the parafoveal …

Effects Of A Dynamic Handgrip Exercise On Left Ventricular Diastolic Functions In Diabetes Mellitus Patients: A Preliminary Clinical Data, Pott Pongpaopattanakul, Thamonwan Imerbtham, Juthamat Kitimala, Suphavech Phatthanawayu, Phattarasuda Kaewkong

Chulalongkorn Medical Journal

Background: A diabetes mellitus (DM) patients sometimes exhibit a pseudo-normal diastolic relaxation during echocardiography examination, which may lead to an incorrect diagnosis. Exercise echocardiography help uncover this hidden alteration, but conventional exercise techniques contain movement artifacts. Recently, an isotonic handgrip exercise was introduced and caused hemodynamic and diastolic changes with less movement. Objective: To investigate hemodynamic and left ventricular diastolic that responses to a dynamic handgrip exercise (DHE) in DM patients. Methods: 12 controls and 12 DM patients were recruited and evaluated for hemodynamic and diastolic functions at rest and 3 minutes after performing DHE. Results: DHE increased systolic blood …