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Full-Text Articles in Medicine and Health Sciences

Impact Of New Thiourea Derivatives On Lipid Peroxidation Adjuvant Arthritis In White Rats, K. Sh. Shukurlaev Mar 2018

Impact Of New Thiourea Derivatives On Lipid Peroxidation Adjuvant Arthritis In White Rats, K. Sh. Shukurlaev

Central Asian Problems of Modern Science and Education

New derivative thiourea and thiocarbamate on oxidation peroxide lipids at adjuvant arthritis at white rat in a clouse. In structure the influence new derivative thiocarbamate and thiourea on peroxide oxidation lipids is investigated at adjuvant arthritis at white rat. Preparation BIK-15 reduce of intensity peroxide lipids and raise of activity enzymes antioxidant of system (SOD, KT) and in this respect they surpass butadione and indometacin


Antiinflammatory Effect Of Herbal Preparations On Adjuvant Arthritis In Rats, Laimis Akramas, Laima Leonaviciene, Ruta Bradunaite, Audrius Vasiliauskas, Irena Dumalakiene, Danguole Zabulyte, Teresa Normantiene, Irena Jonauskiene, Dalia Vaitkiene Jan 2017

Antiinflammatory Effect Of Herbal Preparations On Adjuvant Arthritis In Rats, Laimis Akramas, Laima Leonaviciene, Ruta Bradunaite, Audrius Vasiliauskas, Irena Dumalakiene, Danguole Zabulyte, Teresa Normantiene, Irena Jonauskiene, Dalia Vaitkiene

Turkish Journal of Veterinary & Animal Sciences

The present study aimed to investigate the antiinflammatory effects of 2 herbal extracts (CDS and CDSM) in rats with experimental adjuvant arthritis (AA). Joint swelling, development of polyarthritis, blood indices, pro/antioxidant activity, and proinflammatory cytokine IL-17 in blood serum, as well as the liver and paw histopathology and histochemistry, were assessed. Oral injections of extracts showed an antiinflammatory effect analogous to that of diclofenac (DF), improved blood indices and suppressed level of IL-17, significantly diminished joint swelling, and histological changes in the joints. Increase in CAT activity and AOA and reduction in lipid peroxidation was noted. The preparations did not …