Medicine and Health Sciences Commons^™

Cardiogenic Shock Among Patients With Acute Myocardial Infarction In A Middle Eastern Country: A Single-Centre Experience, Ghada Shalaby, Azmat Khadija Niazi, Sheeren Khaled

Journal of the Saudi Heart Association

BACKGROUND: Cardiogenic Shock (CS) remains the most common cause of death in hospitalized acute ST-segment elevation myocardial infarction (STEMI) patients. Predictors of outcomes in those patients include clinical, laboratory, radiologic variables, and management strategies. The present study aimed to evaluate the incidence, characteristics, predictors of cardiogenic shock and mortality among acute ST-segment elevation myocardial infarction patients in our center METHODS: This was a retrospective, single-center study conducted at KAMC, Makkah during 2015-2020. All acute ST-segment elevation myocardial infarction patients during this era were divided into two groups CS group and non-CS group. RESULTS: In this study total 3074 acute ST-segment …

Value Of Heart Rate Variability, Neutrophil-Lymphocyte Ratio And Quality Of Life Of Patients With Depressive Symptoms In Acute Myocardial Infarction, Hamzah Shatri, Mizanul Adli, Muhadi Muhadi, Murdani Abdullah, Cosphiadi Irawan, Rudi Putranto, Sukamto Koesnoe, Ika Prasetya Wijaya

Jurnal Penyakit Dalam Indonesia

Introduction. Major depression criteria can be found in more than 20% of coronary heart patients and more than 30% acute coronary syndrome patients have significant depressive symptoms. Several studies have shown that reduction of hearth rate variability (HRV) and enhancement of neutrophil lymphocyte ratio (NLR) can cause enhancement of morbidity and mortality in myocardial infarction patients. On the other hand, depression can cause reduction of HRV, enhancement of NLR and reduction of quality of life. This study aimed to determine differences in HRV, NLR and quality of life between acute myocardial infarction (AMI) patients with depressive symptoms and AMI patients …

The Evaluation Of Serum Zinc Level In Patients With Acute Coronary Syndrome And Its Correlation With Cardiac Enzymes, Ahmed El-Kersh, Mina Boktor, Walaa Mosa, Wessam Eldin Hadad El-Shafey

Menoufia Medical Journal

Objective To assess serum zinc level in patients presented with acute coronary syndrome and its relation to cardiac enzymes in acute myocardial infarction (AMI). Background Atherosclerosis is a well-known cause of myocardial infarction owing to accumulation of lipids and fibrous elements in arteries. It was found that there are highly efficient protective mechanisms in the cell, including metal-binding proteins as antioxidants and manganese superoxide dismutase and copper–zinc superoxide dismutase as enzymes. Zinc deficiency can reduce activity of superoxide dismutase linked to atherosclerosis. Patients and methods Our study was carried out in cardiac care units, Menoufia University Hospital, on 100 patients …

When Myocardial Infarction Is Choosing Young Victims, Cristina Nedelcu, Mihaela Ionescu, Paris Ionescu, Vitalie Morosanu, Gabriel Smarandache, Dumitru Cristinel Badiu, Florentina Gherghiceanu, Vlad Denis Constantin, Emanuele Maria Merlo, Daniel Niţă

Journal of Mind and Medical Sciences

We present the case of a 31-year-old patient, without cardiovascular risk factors, without significant pathological or family history of cardiovascular disease, who was diagnosed with severe coronary artery disease, left main bifurcation localization, which required surgical coronary revascularization. The angiographic and intraoperative aspect excluded the most common causes of non-atherosclerotic causes of coronary lesions. Vasculitis was another possible etiology but was also excluded based on the normal clinical examination, negative inflammation markers, lack of diffuse vascular impairment, TPHA and negative VDRL. Prolonged mental stress can lead to accelerated progression of atherosclerosis by inducing endothelial dysfunction, our patient describing a “burnout …

Association Between Off-Hour Presentations And In-Hospital Mortality For Patients With Acute St-Elevation Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention, Elnaz Javanshir, Elham Darzi Ramandi, Samad Ghaffari, Babak Nasiri, Haleh Bodagh, Ghiti Davarmoin, Naser Aslanabadi, Ahmad Separham

Journal of the Saudi Heart Association

Objectives: This study aimed to assess the effect of the admission time (on-hours versus off-hours) on in-hospital mortality in patients with ST-elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PPCI) in a region without STEMI network.

Methods: We analysed in-hospital the mortality among 300 consecutive ST-segment elevation myocardial infarction (STEMI) patients treated with PPCI between March 2012 and February 2017. Patients were divided according to admission time into on-hours admission (08:00 AM until 08:00 PM on weekdays) versus off-hours admission (08:00 PM until 08:00 AM on weekdays and 24 h on weekends and holidays). Demographic and clinical …

Occurence Of Left Main Occlusion On Tuesday: Chronobiology Of Acute Myocardial Infarction, Gianluca Rigatelli, Marco Zuin

Journal of the Saudi Heart Association

Objectives: The existence of a “weekend effect” for onset of acute myocardial infarction (AMI) has been suggested in the past, but the relation with the culprit vessel has not been investigated. MI due to left main coronary artery lesion represents a particularly serious life-threatening condition. Our study was aimed to assess the chronobiology of admission to the emergency department for AMI considered to be induced by a left main culprit lesion. Methods: We retrospectively reviewed patients who experienced an AMI due to a left main culprit lesion between January 1, 2008 and January 1, 2018 stratifying them according to the …

Acute Myocardial Infarction Triggered By Influenza: Role Of Vaccine In Its Prevention, Nischit Baral, Suman Sharma, Subash Ghimire, Sanjay Poudel, Savyata Hamal, Nisha Baral, Niranjan Nayak

Manipal Journal of Medical Sciences

Influenza is a major cause of hospitalization in all age groups. Cardiovascular complications due to influenza are important causes of morbidity and mortality in the US, especially in the elderly population (aged more than 65 years). Acute Myocardial Infarction (AMI) is the most serious among the cardiovascular causes of mortality following the attack of influenza, mainly in patients with various co-morbidities like pre-existing coronary artery disease (CAD), diabetes mellitus (DM), hypertension (HTN) and heart failure (HF). We have reviewed the association between influenza virus infection and AMI and extrapolated the beneficial effects of influenza vaccine in preventing AMI and its …

Electrocardiographic Prediction Of Culprit Artery In Acute St-Segment Elevation Myocardial Infarction, Abdulla M. Kamal, Ghada M. Soltan, Momen A. A. Ali

Menoufia Medical Journal

Background Early prediction of the site and proximity of the occlusion in the culprit artery is essential from a clinical point of view. Objective This study aimed to assess the accuracy of previously defined ECG criteria determined from ECG angiographic correlative studies in predicting not only the infarct-related artery but also the site of the culprit lesion within that artery. Patients and methods ECG and angiographic findings were correlated in 187 patients with an ST-segment elevation myocardial infarction (STEMI). Results In the first group (Anterior ST elevation Myocardial infarction; STEMI), ECG criteria that predict the angiographic findings showed sensitivity and …

Circulating Cell-Free Dna As A Sensitive Biomarker In Patients With Acute Myocardial Infarction, Abd-Allah M. Kamal, Eman S. Arafat, Eman A. Badr, Esam-Eldin I. Radwan, Ibrahim Elmadbouha, Naglaa M. Ghanayem

Menoufia Medical Journal

Objective The aim of this study was to evaluate the role of circulating cell-free DNA as an early cardiac biomarker in patients with acute myocardial infarction (AMI). Background Circulating cell-free DNA mainly originates from programmed cell death or acute cellular injury and reflects the extent of cellular damage. Patients and methods This study was carried out on AMI patients (n = 50) and healthy controls (n = 30). All participants were subjected to a full assessment of history, clinical examination, ECG, and echocardiography. Blood samples were taken for cardiac biomarkers, kidney function tests, liver enzymes, lipid profiles, and …

Diagnostic Impact Of Serum Myoglobin And Human Heart-Type Fatty Acid Binding Protein In Patients With Acute Myocardial Infarction, Emtiaz F. Amin El-Lakwah, Mahmoud A. Soliman, Naglaa M. Ghanayem, Said S. Montaser, Walaa F. Abd El-Aziz

Menoufia Medical Journal

Objective: The aim of the study was to assess the value of the serum concentrations of myoglobin and human heart-type fatty acid binding protein (H-FABP) in the early detection of acute myocardial infarction (AMI). Background: Myoglobin and H-FABP are useful as biochemical markers of muscle injury. We conducted this investigation to detect whether both markers and their ratio were useful in the early detection of AMI. Patients and methods: This study included 21 patients with AMI, 20 patients with skeletal muscle injury, and 10 normal healthy individuals. Their blood samples were obtained (within 6 h of onset of chest pain …

Assessment Of Right Ventricular Function In Patients With First Inferior Myocardial Infarction: Strain Imaging Study, Ahmed A. Reda, Hesham M. Saad Tayel, Mohamed F. El-Noamany, Naglaa F. Ahmed

Menoufia Medical Journal

Objective: The aim of the study was to assess strain and strain rate (SR) properties of the right ventricle (RV) in patients with RV myocardial infarction (MI). Background: Quantitative assessment of RV function is still challenging due to its complex anatomy and thin wall structure, and therefore is not incorporated into daily clinical practice. Two-dimensional strain and SR analyses are novel Doppler-independent techniques to obtain these measurements of myocardial movement and deformation. These methods have been frequently used to assess left ventricular function; however, they have yet rarely been used to examine RV function, despite RV function is an important …

St-Segment Elevation Myocardial Infarction In Patient With Left Ventricular Assist Device, Navin Rajagopalan, Ryan E. Wilson

The VAD Journal

Acute myocardial infarction is a rare event in a patient with a left ventricular assist device (LVAD). We present a case of ST-segment elevation myocardial infarction in a LVAD patient.

The Application Of Age-Predicted Maximal Heart Rate In Acute Myocardial Infarction Patients, Yan-Wen Chen, Yan-Kai Wen, Shyi-Kuen Wu, Chih-Yang Tang, Shin-Tsu Chang, Shin-Shan Lu

Rehabilitation Practice and Science

Heart rate is a very simple measurement values, can be used to monitor reaction of the heart to exercise response. The maximum heart rate is widely used for clinical diagnosis, exercise tolerance and exercise prescription for related diseases. The traditional formula for predicting maximum heart rate (220-age) prediction formula has large errors (overestimation or underestimation) phenomenon may overestimate or underestimate heart rate values, and thus may not reflect the actual amount of stress on the heart. Acute myocardial infarction is a common heart disease in the clinical setting. The safety and effectiveness of exercise intensity is particularly important in post-myocardial …

Cardiac Rehabilitation Among Patients With Acute Myocardial Infarction Receiving Percutaneous Coronary Intervention After Acute Myocardial Infarction Indicator Was Activated, Yu-Yang Hung, Su-Ying Hung, Chen-Liang Chou, Shih-Ann Chen

Rehabilitation Practice and Science

Background and Purpose: Cardiac rehabilitation (CR) is effective in improving mortality and morbidity outcomes and may favorably influence cardiac risk factors in patients with coronary heart disease. Despite the proven benefits, CR remains considerably under-utilized worldwide. The aim of this study was to research the current status of CR for patients with acute myocardial infarction (AMI) receiving percutaneous coronary intervention (PCI) after the Taiwan Clinical Performance Indicator executes was activated in a medical center in Taiwan. Methods: The medical records of 174 patients with AMI at our hospital from January to December 2012 were retrospectively reviewarticleed to investigate the consultation …

Gender Difference In Acute Myocardial Infarction Patients Receiving Phase 1 Cardiac Rehabilitation, Chi-Che Ho, Yi-Ru Chen, Chung-Han Ho, Wen-Chih Lin, Shu-Han Yang, Hui-Chun Juan, Willy Chou

Rehabilitation Practice and Science

Purpose: The effects of gender difference on the pathogenesis, epidemiology, diagnosis, treatment, and prognosis of cardiovascular diseases have been widely examined. In addition, gender differences influence cardiac rehabilitation; however, few studies have investigated the effect of gender difference on phase 1 cardiac rehabilitation patients. Therefore, this study explored gender difference in acute myocardial infarction patients who received phase 1 cardiac rehabilitation based on data collected from the National Health Insurance Research Database. For our analysis, we focused on the age distribution, comorbidities, and medical treatment of these patients. The study results are expected to serve as a reference for cardiac …

Recovery Of Regional And Global Left Ventricular Systolic Function After Acute Myocardial Infarction: A Comparative Study Between Emergency Percutaneous Coronary Intervention And Fibrinolytic Therapy, Mohamed Salem, Shaimaa Mostafa

Menoufia Medical Journal

Objectives Quantitative assessment of the recovery of regional and global left ventricular systolic function after reperfusion in acute myocardial infarction. Background Left ventricular systolic function is an important predictor of the outcome after acute myocardial infarction. Patients and methods The study included 60 patients with first-time acute myocardial infarction: 30 were treated with fibrinolytic therapy (the pharmacological subgroup) and 30 with emergency percutaneous coronary intervention (the invasive subgroup). Evaluation was performed at 1 week and after 30 days by conventional echocardiography, tissue Doppler imaging, and two-dimensional strain (global longitudinal peak systolic strain). Results About 47% of the study population was …

Acute Myocardial Infarction After Blunt Chest Trauma, Sivakumar Srinivasan, Md, Sandeep Anreddy, Md, Paul Mather, Md

The Medicine Forum

Coronary artery injury rarely occurs after blunt chest wall trauma. It can, however, lead to extensive myocardial infarction. We report a rare case of acute anterolateral myocardial infarction in a young man after blunt chest trauma.

The Relationship Between Plasma Homocysteine And Early Coronary Collateral Vessel Development After Acute Myocardial Infarction, Telat Keleş, Tahi̇r Durmaz, Ni̇hal Akar Bayram, Murat Akçay, Ekrem Yeter, Hüseyi̇n Ayhan, Engi̇n Bozkurt

Turkish Journal of Medical Sciences

Aim: Homocysteine is known to inhibit endothelial cell proliferation, which is a key event in angiogenesis. Factors responsible for the presence or absence of coronary collateral circulation are poorly understood. Therefore, in this study we investigated the effect of plasma homocysteine level on the early formation of angiographically visible collaterals after acute myocardial infarction. Materials and Methods: The study included 60 patients that had ST-segment elevation myocardial infarction (STEMI). All the patients underwent coronary angiography 1-4 days after admission (mean: 2.3 ± 1.2 days). Patients were graded according to Rentrop classification. Patients with grade 0 or 1 collateral vessels were …

The Role Of Heart-Type Fatty Acid-Binding Protein (H-Fabp) In Acute Myocardial Infarction (Ami) Compared To Conventional Cardiac Biochemical Markers, Hati̇ce Paşaoğlu, Ebru Ofluoğlu, Mustafa İlhan, Ati̇ye Çengel, Murat Özdemi̇r, Emre Durakoğlugi̇l, Murat Erden

Turkish Journal of Medical Sciences

Aim: To investigate the clinical implications of serum heart-type fatty acid-binding protein (H-FABP) compared to myoglobin, cardiac troponin I (cTnI), and creatine kinase MB isoenzyme (CK-MB) in patients with early phase acute myocardial infarction (AMI). Material and Methods: Patients were grouped clinically according to the American College of Cardiology/European Society of Cardiology new definition of myocardial infarction (MI) and by clinician diagnosis of MI. Serum concentrations of H-FABP, myoglobin, cTnI, and CK-MB were determined in 21 patients with AMI and 44 non-AMI patients. From each patient 3 blood samples were obtained 1-2, 3, and 6 h after the onset chest …

Serum Cholesterol Values In Acute Myocardial Infarctionpatients At King Chulalongkorn Memorial Hospital, Su. Suppapitiporn

Chulalongkorn Medical Journal

No abstract provided.

The Long-Term Clinical Prognosis In Patients With Anterior Wall And Non-Anterior Wall Acute Myocardial Infarction Referred To Primary Percutaneous Transluminal Coronary Angioplasty, Mingzhong Zhao, Dayi Hu, Tianchang Li, Sanqing Jia

Journal of the Hong Kong College of Cardiology

Objective: To investigate the long-term clinical prognosis in patients with anterior wall acute myocardial infarction (AW-AMI) and non AW-AMI (NAW-AMI) referred to primary percutaneous transluminal coronary angioplasty (P-PTCA). Methods: 287 patients with AMI who underwent P-PTCA were divided into AW-AMI group (142 cases) and NAW AMI group (145 cases) according to different sites of AMI. The baseline characteristics and coronary artery lesions of patients were analysed. The primary end points were in-hospital mortality and the major cardiovascular events (MACE) during a mean 17.3±9.8 months follow-up including the occurrences of non-fatal myocardial infarction, non-fatal congestive heart failure, revascularization of target vessels …

The Effects Of Ticlopidine In Acute Myocardial Infarction As An Adjunctive Treatment To Aspirin In An Intermediate Term Setting, V. Gökhan Ci̇n, Ahmet Temi̇zhan, Hasan Pekdemi̇r, Mehmet Tokaç, Okan Tartanoğlu

Turkish Journal of Medical Sciences

Antiplatelet therapy reduces the risk of subsequent ischemic events in patients suffering from acute myocardial infarction (AMI). In this respect, the multi-agent therapy to be used along with aspirin remains to be determined. In this study, ticlopidine was tried in AMI for its potential additive effects over aspirin. Ninety patients with similar clinical characteristics were involved and were followed up for 3 and 6 months. All patients were assigned to receive ticlopidine plus aspirin or aspirin alone. Major cardiac events such as death and reinfarction were primary end-points whereas the need for revascularization was the secondary end-point at 3 and …

Patients With Irritable Bowel Syndrome : Possiblehypersensitivity To Capsicum, D. Thong-Ngam, S. Treeprasertsuk, A. Sriatanaban

Chulalongkorn Medical Journal

No abstract provided.

Blood Lactate/Pyruvate As A Predictor Of Shockdevelopment In Acute Myocardial Infarction, Arzu Seven, Sabiha Ci̇velek, Figen Kocaman, Lale Koldaş, Gülden Candan

Turkish Journal of Medical Sciences

This study, designed to investigate the blood lactate and pyruvate levels in AMI, was carried out on 41 patients. Based upon the localization of AMI, the patients were studied under anterior AMI (n=17), anteroseptal AMI (n=9) and inferior AMI (n=15) groups. Left ventricular failure developed in five patients with anterior AMI and in one patient with anteroseptal AMI. Cardiogenic shock developed in two patients with anterior AMI. Lactate and pyruvate were analysed in the blood samples drawn 24-48 hours after AMI. CPK, CPK-MB, AST and LDH activities were determined in the sera of blood samples drawn within 6-24 hours of …

Cardiac Troponin T In Diagnosis Of Acute Myocardial Infarction, Gülinnaz Alper, Ömür Erkizan, Can Hasdemi̇r, Azem Akilli, Taner Onat

Turkish Journal of Medical Sciences

Cardiac Troponin T (TnT) is a regulatory contractile protein not normally found in blood. Its detection in the circulation has been shown to be a sensitive and specific marker for myocardial cell damage. This study was designed to evaluate the diagnostic efficiency of TnT enzyme immunoassay for the early diagnosis of AMI (Acute Myocardial Infarction) and to compare this newly developed test with the conventionally used cardiac enzyme tests in need of an alternative test of greater sensitivity and specificity. The study population consisted of 13 patients with a mean age of 52±8 years who were hospitalized for AMI. Blood …