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Full-Text Articles in Medicine and Health Sciences
Is Detection Of Preclinical Alzheimer’S Disease Possible?, Shana Brawer
Is Detection Of Preclinical Alzheimer’S Disease Possible?, Shana Brawer
The Science Journal of the Lander College of Arts and Sciences
No abstract provided.
Possible Causes Of Alzheimer’S Disease Related Amyloid-Β Plaques And Neurofibrillary Tangles, Rochelle Rubenstein
Possible Causes Of Alzheimer’S Disease Related Amyloid-Β Plaques And Neurofibrillary Tangles, Rochelle Rubenstein
The Science Journal of the Lander College of Arts and Sciences
Alzheimer’s disease is a major cause of dementia in the elderly and is a global health concern. However, researchers are not sure what causes the characteristic amyloid-β plaque accumulation and neurofibrillary tangles in the brain. Several model mechanisms have been proposed to answer this question. This paper examines three of these possibilities. Research suggests that a particular allele of the apoE gene is responsible for the neurodegeneration found in Alzheimer’s disease. Another hypothesis is that the mechanism of Alzheimer’s is related to prion-mediated protein misfolding. Other studies indicate that certain environmental factors can cause the neuropathology of Alzheimer’s. Specifically, this …