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Full-Text Articles in Medicine and Health Sciences
Are Contact Lenses An Effective Vehicle For Ocular-Disease Drug Delivery?, Chana Haimowitz
Are Contact Lenses An Effective Vehicle For Ocular-Disease Drug Delivery?, Chana Haimowitz
The Science Journal of the Lander College of Arts and Sciences
Due to numerous drawbacks with current modes of treatment for various ocular diseases, researchers are synthesizing drug dispensing contact lenses. The lenses will contribute to greater bioavailability of the drug, the minimization of negative side effects, and increased patient compliance. As treatment for glaucoma, in vivo studies have been conducted with latanoprost, timolol maleate, and brimonidine tartrate-eluting lenses, and have succeeded in reducing intraocular pressure to desired values (Ciolino et al., 2016), (Schultz and Mint, 2002). As treatment for fungal keratitis, in vitro studies prove that econazole and natamycin-eluting contact lenses have been successful in killing 100% of fungi for …
Stem Cell Therapy And Macular Degeneration, Brenda Stern
Stem Cell Therapy And Macular Degeneration, Brenda Stern
The Science Journal of the Lander College of Arts and Sciences
Macular degeneration is the leading cause of vision loss in Americans sixty years and older. Currently, it is an incurable disease. Stem cell therapy is the idea of transplanting stem cells to replace damaged cells in the body. As the demand for transplantable organs far outweighs the supply, stem cells are an encouraging alternative to replace damaged cells. Can stem cell therapy be the first cure for macular degeneration? Many experiments have been done on transplanting stem cells into the eyes of rats with macular degeneration yielding promising results. The first transplantation of retinal pigmented epithelial stem cells into humans …
The Rehabilitative Potential Of Auditory To Visual Sensory Substitution Devices For The Blind, Naomi Perl
The Rehabilitative Potential Of Auditory To Visual Sensory Substitution Devices For The Blind, Naomi Perl
The Science Journal of the Lander College of Arts and Sciences
Living with a sensory impairment is challenging, and those who have lost the use of one sensory modality need to find ways to deal with numerous problems encountered in daily life. When vision is lost, these challenges include navigation through space, finding objects, recognizing people or surroundings, reading or even communicating without access to nonverbal signs provided by others such as eye gaze or facial expressions. Nevertheless, the blind manage to function efficiently in their environment, often to a surprisingly high degree. The key to this amazing phenomenon lies in the plasticity of the brain and the connections it makes …
Environmental Factors And Progressive Myopia: A Global Health Problem, Jeffrey Weissman
Environmental Factors And Progressive Myopia: A Global Health Problem, Jeffrey Weissman
The Science Journal of the Lander College of Arts and Sciences
Myopia, or nearsightedness, is a refractive error whose prevalence has increased over the past three decades, leading to a growing concern and interest among both the public and scientific communities. For years, the only explanation and basis for myopia has been genetic factors. However, the genetic model does not explain the dramatic increase in prevalence. Current research suggests that the increase is also due to environmental factors, such as fewer hours of outdoor activities, early educational pressures requiring intense close work, as well as a lack of exposure to sunlight. One study compared the prevalence and risk factors for myopia …
Excitoxicity In Retinal Ischemia And Treatment Using Non-Competitive Receptor Antagonists, Jacob Rube
Excitoxicity In Retinal Ischemia And Treatment Using Non-Competitive Receptor Antagonists, Jacob Rube
The Science Journal of the Lander College of Arts and Sciences
The following is an excerpt from the article: Ischemia is defined as an inadequacy of blood flow to tissue. Ischemia can deprive tissue of oxygen and metabolic substrates and it can also prevent the removal of waste products. If the ischemia is maintained over enough time the tissue will lose its homeostasis and eventually die causing an infarct. Retinal ischemia occurs when the blood supply to the retina does not meet the metabolic needs that are required to sustain the retina. This can lead to retinal damage and severe vision loss. Ischemia is caused by occluded blood vessels.